Gene Information

Name : tktB (t0385)
Accession : NP_804254.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 459006 - 461006 bp
Length : 2001 bp
Strand : -
Note : 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exp

DNA sequence :
ATGTCCCGTAAAGACCTTGCCAATGCGATTCGTGCGCTGAGCATGGATGCCGTTCAAAAAGCCAATTCCGGGCACCCCGG
CGCGCCGATGGGGATGGCGGATATCGCTGAAGTGCTATGGAACGATTTTCTTAAACATAACCCCACCGATCCGACCTGGT
ATGACCGTGATCGTTTTATCCTTTCCAACAGTCACGCCTCCATGCTGCTCTATAGTCTGCTGCATTTAACCGGGTATGAC
CTGCCGCTGGAGGAGCTAAAAAACTTCCGTCAACTGCACTCTAAAACGCCTGGTCACCCGGAGATTGGCTATACGCCTGG
CGTTGAAACCACCACCGGGCCGCTGGGCCAGGGGCTGGCGAATGCCGTCGGGCTGGCGATTGCCGAGCGTACGTTAGGCG
CACAGTTCAACCGGCCGGACCATGAGATTGTCGACCACTACACCTATGTCTTTATGGGCGACGGCTGTCTGATGGAGGGG
ATCTCGCATGAGGTGTGTTCGCTGGCTGGTACGCTGGGACTGGGCAAACTGATCGGCTTTTACGATCACAACGGCATCTC
CATTGATGGCGAAACCGAAGGCTGGTTTACCGACGATACAGCCAAACGTTTTGAAGCCTACCACTGGCATGTCGTGCATG
ACATTGACGGGCACGCTCCGGAGGCGGTGAAAAAAGCCATTCTGGAAGCCCAGAGCGTAAAAGATAAACCTTCGCTAATT
ATCTGTCGGACGGTGATAGGTTTTGGCTCGCCGAATAAAGCCGGGAAGGAGGAGTCGCACGGCGCGGCGCTGGGCGAAGA
AGAGGTGGCGCTGACCCGCCAGAAGCTGGGATGGCATCATCCGGCGTTTGAGATCCCAAAAGAGATTTACCGCGCGTGGG
ATGGCCGTGAAAAAGGCGAGAAAGCGCAGCAGCAGTGGCAGGAAAAGTTTGCTGCTTATGAGAAGGCTTATCCTGAGCTG
GCCGCGGAGTTTACCCGCCGGATGAGCGGCGGATTGCCGGAGGCATGGGAATCCGCCACGCAAAAATTTATTAACGACTT
GCAGGCTAATCCGGCCAAAATCGCCACCCGTAAAGCATCGCAAAATACGCTCAATGCCTATGGTCCCCTGTTGCCGGAAC
TGTTGGGCGGATCGGCGGATCTGGCGCCGAGCAACCTGACTATCTGGAAAGGTTTGACCTCGTTGAAAGAGGATCCGGCA
GGTAATTACATCCACTATGGCGTGCGCGAATTCGGCATGACCGCCATTGCCAACGGCATCGCCCACCACGGCGGCTTTGT
ACCGTATACCGCCACGTTTCTGATGTTTGTCGAATATGCGCGTAACGCGGCGCGTATGGCGGCCTTAATGAAAGCCCGGC
AGATTATGGTCTATACCCACGACTCCATCGGTTTGGGCGAAGATGGCCCGACGCACCAGGCCATGGAACAACTGGCGAGC
CTGCGCTTAACGCCTAACTTCAGCACCTGGCGTCCCTGCGATCAGGTTGAGGCGGCAGTCGGTTGGAAGCTGGCCATTGA
ACGTCAGCACGGGCCGACGGCGTTGATTCTCTCGCGGCAGAATCTGGCGCAGGTGGAACGCACGCCGGAACAGGTGAAAG
CGATTGCCCGCGGCGGTTATATTCTGAAAGATAGCGGCGGCAAGCCGGATATCATTCTGATCGCTACCGGATCGGAAATG
GAAATTACCCTCCAGGCGGCGGAAAAATTGACTGGCGAGGGGCATAACGTTCGGGTGGTGTCGTTGCCTTCAACGGATAT
TTTCGATGCGCAGGACGAGGCATATCGCGAATCAGTGCTACCGGCGCACGTAACCGCCCGCGTCGCGGTGGAGGCCGGTA
TAGCCGACTACTGGTATAAATATGTTGGCCTAAAAGGCGCAATTATCGGCATGACGGGATACGGTGAATCCGCCCCGGCT
GACAAACTGTTCCCGTATTTTGGCTTTACCGTGGAAAATATTGTGGAAAAAGCCCGCCGGGTGCTGAACATCAAAGGCTA
A

Protein sequence :
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNSHASMLLYSLLHLTGYD
LPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLGAQFNRPDHEIVDHYTYVFMGDGCLMEG
ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVVHDIDGHAPEAVKKAILEAQSVKDKPSLI
ICRTVIGFGSPNKAGKEESHGAALGEEEVALTRQKLGWHHPAFEIPKEIYRAWDGREKGEKAQQQWQEKFAAYEKAYPEL
AAEFTRRMSGGLPEAWESATQKFINDLQANPAKIATRKASQNTLNAYGPLLPELLGGSADLAPSNLTIWKGLTSLKEDPA
GNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGEDGPTHQAMEQLAS
LRLTPNFSTWRPCDQVEAAVGWKLAIERQHGPTALILSRQNLAQVERTPEQVKAIARGGYILKDSGGKPDIILIATGSEM
EITLQAAEKLTGEGHNVRVVSLPSTDIFDAQDEAYRESVLPAHVTARVAVEAGIADYWYKYVGLKGAIIGMTGYGESAPA
DKLFPYFGFTVENIVEKARRVLNIKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 74
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 65