Gene Information

Name : metB (t3518)
Accession : NP_807166.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3620202 - 3621362 bp
Length : 1161 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGACGCGTAAACAGGCCACTATCGCAGTGCGTAGCGGATTAAACGATGACGAACAATACGGCTGCGTTGTGCCGCCAAT
CCATCTCTCCAGTACCTATAACTTTACCGGTTTCAATGAGCCGCGCGCGCATGATTATTCCCGCCGCGGTAATCCCACGC
GTGATGTGGTTCAGCGCGCATTAGCGGAACTGGAAGGCGGCGCGGGCGCAGTATTGACGAATACCGGCATGTCGGCGATT
CATCTGGTCACCACCGTTTTCCTCAAGCCGGGCGATCTGCTGGTCGCGCCGCATGATTGCTACGGCGGCAGTTATCGTCT
GTTTGACAGTCTGGCGACGCGCGGCTGTTATCGTGTGCGGTTTGTCGATCAGGGCGATGAACGCGCCTTACAGGCGGCGC
TGGAAGAAAAACCGAAGCTGGTACTGGTAGAAAGTCCAAGTAATCCATTGTTACGCGTGGTGGATATTGCGAAAATCTGT
CGGCTGGCGCGCGAGGCGGGCGCAGTGAGCGTCGTTGATAACACATTTTTAAGCCCGGCGCTGCAAAATCCGCTGGCGTT
GGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTCAATGGTCATTCGGATGTCGTGGCCGGCGTGATGATTGCTA
AGGATCCGGAAATGGTCACTGAACTGGCGTGGTGGGCGAATAATATTGGCGTGACCGGCGGGGCGTTTGATAGCTATCTG
CTGCTGCGCGGTTTGCGAACTCTGGTGCCGCGTATGGAGCTGGCGCAGCGCAACGCGCAGGCGATTGTGAAATATCTGCA
AACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGAATAATCAGGGACATGAGATTGCCGCGCGTCAGCAAA
AAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGGGATGAGGAGACGCTACGTCGTTTTCTGGGCGGGCTGTCGCTG
TTTACGCTGGCGGAATCTTTAGGGGGAGTGGAAAGTTTGATCTCTCACGCCGCCACCATGACGCATGCCGGTATGTCGCC
GCAGGCGCGTGCCGCCGCCGGGATCTCCGAAACGCTACTGCGTATCTCCACCGGTATTGAAGATGGCGAAGATTTAATTG
CCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
RLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVMIAKDPEMVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPNNQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMSPQARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-62 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-51 41