Gene Information

Name : thiC (t3467)
Accession : NP_807123.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3555807 - 3557702 bp
Length : 1896 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTACAACAACGTTAACCCGCCGCGAGCAGCGCGCTAAAGCCCAGCATTTTATCGATACGCTGGAAGGGACTGCCTT
TCCCAACTCGAAACGCATCTACGTGACCGGTTCGCAGCATGATATTCGCGTACCGATGCGCGAAATTCAACTTAGCCCTA
CGCTCATCGGCGGCAGTAAAGACAACCCGCAGTTTGAAGAGAACGAAGCCGTACCGGTATACGACACCTCCGGCCCCTAT
GGCGATCCTGAAGTGGCGATTAACGTCCAGCAGGGTCTGGCGAAACTGCGCCAGCCGTGGATTGACGCACGTAACGATAG
CGAAGAATTAGACGACCGTAGCTCGGCTTACACCAGAGAACGTCTGGCCGACGATGGCCTGGACGATCTGCGTTTTACCG
GCCTGCTGACGCCGAAACGCGCTAAAGCGGGCAAGCGCGTCACCCAGTTACACTACGCCCGCCAGGGGATCGTCACTCCC
GAAATGGAGTTCATCGCCATCCGTGAAAACATGGGCCGCGAGCGCATTCGCAGTGAAGTGCTGCGCCACCAGCATCCGGG
CATGAACTTTGGCGCGCGCCTGCCGGAAAACATTACGCCGGAATTCGTGCGTGATGAAGTCGCCGCGGGCCGCGCGATTA
TTCCCGCCAACATCAACCACCCGGAATCGGAGCCGATGATTATCGGCCGCAACTTCCTGGTCAAAGTGAATGCCAACATC
GGTAACTCGGCGGTCACCTCCTCCATCGAAGAAGAGGTCGAGAAGCTGGTGTGGTCAACCCGCTGGGGCGCGGACACGGT
GATGGACCTCTCCACCGGTCGCTATATTCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCGGCACCG
TCCCGATCTACCAGGCGCTGGAAAAGGTCAACGGGATCGCCGAAGATCTCACCTGGGAAGCGTTCCGCGACACGCTGCTG
GAGCAGGCCGAACAGGGCGTCGACTACTTCACCATCCACGCCGGCGTGCTGCTGCGCTACGTGCCGATGACCGCCAAACG
CCTGACCGGTATTGTCTCGCGCGGCGGTTCGATCATGGCAAAGTGGTGTCTCTCCCATCACAAAGAGAACTTCCTGTTCG
AACATTTCCGCGAGATTTGTGAAATCTGCTCCGCCTACGACGTTTCCCTGTCGCTGGGCGACGGCCTGCGCCCCGGCTCC
ATTCAGGACGCCAACGACGAAGCGCAGTTCTCCGAGCTGCATACGCTGGGCGAGCTGACCAATATCGCCTGGGAATACGA
CGTGCAGGTGATGATTGAAGGCCCGGGCCACGTGCCGATGCATATGATTCAGCGCAACATGACCGAAGAGCTGGAGAGCT
GCCACGAAGCGCCGTTCTACACCTTAGGGCCGTTGACCACCGATATCGCGCCGGGCTATGACCACTTCACCTCTGGCATT
GGCGCGGCGATGATCGGCTGGTTTGGCTGCGCGATGCTGTGTTACGTGACGCCGAAAGAGCATCTCGGCCTGCCGAACAA
AGAAGATGTGAAGCAGGGGCTGATCACCTACAAAATCGCCGCCCACGCCGCGGATTTAGCCAAAGGACATCCGGGCGCGC
AGATCCGCGATAACGCCATGTCGAAAGCGCGCTTTGAATTCCGCTGGGAAGATCAGTTTAACCTCGCGCTCGACCCGTTC
ACCGCCCGCGCTTATCACGATGAAACCCTGCCGCAGGAGTCCGGTAAGGTCGCCCACTTCTGTTCCATGTGTGGGCCGAA
GTTCTGCTCAATGAAAATCAGCCAGGAAGTGCGTGATTACGCCGCCGCGCAAGCCATTGAAGTCGGCATGGCGGATATGT
CGGAGAACTTCCGCGCCAAAGGCGGCGAAATTTATCTCAAACGGGAGGAAGCCTGA

Protein sequence :
MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRVPMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPY
GDPEVAINVQQGLAKLRQPWIDARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTP
EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICSAYDVSLSLGDGLRPGS
IQDANDEAQFSELHTLGELTNIAWEYDVQVMIEGPGHVPMHMIQRNMTEELESCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 70