Gene Information

Name : hemC (t3359)
Accession : NP_807027.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3460640 - 3461581 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAATGTTTTAAGAATTGCCACACGCCAAAGTCCCCTTGCGCTTTGGCAGGCACATTATGTCAAAGACGCATT
GATGGCAACCCATCCGGGACTGACGGTAGAACTGGTGCCGATGGTCACACGCGGCGACGTGATTCTCGATACTCCCCTGG
CGAAAGTGGGCGGTAAGGGACTGTTTGTTAAAGAGCTTGAAATCGCGCTGCTGGAAAAACGCGCTGATATCGCCGTGCAC
TCTATGAAAGACGTTCCGGTGGCCTTCCCGGACGGTCTCGGTCTGGTGACCATTTGCGAGCGCGAAGATCCGCGCGACGC
GTTTGTCTCGAATAAATATCACAGTCTGGACGATCTGCCCGCGGGTAGTATCGTCGGGACGTCCAGTTTGCGTCGTCAGT
GTCAACTGGCGGAACGCCGTCCGGATCTCATTATCCGTTCGTTGCGCGGCAACGTCGGCACACGTCTCGGCAAGCTGGAT
AACGGCGACTATGACGCCATTATCCTGGCCGTGGCCGGTCTGAAACGCTTAGGTCTGGAGTCGCGCATTCGCACAGCCTT
GCCGCCTGACGTTTCGCTTCCTGCCGTAGGCCAGGGCGCTGTCGGGATTGAGTGTCGTCTTGACGACGCGCGAACACAGG
CGCTGCTCGCACCGTTGAATCACTCGCAAACCGCGCTGCGCGTAACGGCGGAACGTGCTATGAACACCCGCCTGGAAGGC
GGTTGTCAGGTGCCGATTGGCAGCTATGCAGAAATCATCAACGGTGAAATTTGGCTACGCGCGCTGGTTGGCGCGCCGGA
CGGTTCGGTGATGGTGCGCGGCGAACGTCGTGGTTCTCCCGAGCAGGCGGAGCAAATGGGCATCTCGCTTGCAGAGGAAC
TGCTGGAAAACGGCGCGCGCGCGATTCTGACGGAAGTTTATAACGGCGAGACGCCCGCATGA

Protein sequence :
MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVH
SMKDVPVAFPDGLGLVTICEREDPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLD
NGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAPLNHSQTALRVTAERAMNTRLEG
GCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGERRGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-86 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-86 61