Gene Information

Name : cadB (t0298)
Accession : NP_804174.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 340895 - 342226 bp
Length : 1332 bp
Strand : -
Note : antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGAGTTCTGTCAAAAAGATCGGGCTATTTGCCTGTACTGGCGTCGTTGCCGGTAATATGATGGGGAGCGGGATTGCATT
ATTACCCGCCAACCTTGCCAGTATTGGTGGCATTGCCATCTGGGGCTGGGTAATTTCTATTATTGGGGCAATGTCGCTGG
CTTATGTTTATGCGAGGCTGGCAACCAAAAACCCGCAACAGGGTGGCCCTATCGCTTATGCTGGGGAAATATCTCCGGCG
TTTGGTTTCCAGACCGGCGTTCTTTATTATCACGCAAACTGGATTGGTAACTTAGCCATCGGTATTACCGCGGTTTCTTA
TCTTTCTACGTTCTTCCCGGCATTAAATAATCCAATACCGGCAGGTATTGCCTGTATTGCTATCGTCTGGCTGTTCACCT
TTATTAATATGCTGGGCGGGGCCTGGGTCAGCCGCTTGACAACGATTGGCCTGTTTCTGGTGCTGATCCCGGTAGTCTTG
ACCGCAGTCGCCGGCTGGCATTGGTTCGCTATCGCGACCTATCACGCGAACTGGAACACGTCTACGACGACCGACTCTCA
CGCCATTGTTAAAAGTATTCTGCTCTGCCTGTGGGCGTTCGTTGGCGTTGAGTCTGCCGCCGTCAGCACCGGCATGGTGA
AAAACCCGAAACGCACCGTACCGCTGGCAACCATGCTGGGTACCGCGCTGGCAGGCATCATCTATATCGCCGCGACTCAG
GTTATCGCCGGGATGTTCCCAGCTTCCGTTATGGCCTCTTCCGGCGCGCCGTTCGCTATCAGTACCTCCACGATTCTGGG
TGGCTGGGCTGCGCCGCTGGTTTCCGCCTTTACCGCTTTCGCCTGCCTGACGTCTCTGGGCTCCTGGATGATGCTGGTCG
GCCAGGCTGGGGTTCGCGCCGCCAACGACGGCAACTTCCCGAAAATTTACGGTGAAATGGATAAAAACGGTATTCCGAAA
AAAGGTCTGCTGTTGGCTGCGGTGAAAATGACGGCGCTGATGATTCTGATCACCATCATGAACTCCAGCGGCGGTAAAGC
GTCCGACCTGTTCGGCGAACTGACCGGGATTGCCGTACTGCTTACCATGCTGCCGTACTTCTACTCTTGTGTTGACCTGA
TTCGTTTCGAAGGGTTCAACATCCGTAACTCGGTAAGCCTGATTTGTTCTGTACTGGGCTGCGCATTTTGCTTCATCGCA
CTGATGGGCGCCAGCTCCTTCGAACTCTCCGGCACCTTTATCGTCAGTCTGATCATCCTGATGTTCTACGGTCGCAAAAT
GCACCAGCGCCAGAACAACGACAGCGACAACAATACGGCTGAAGCGCTTTAA

Protein sequence :
MSSVKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWVISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPA
FGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPALNNPIPAGIACIAIVWLFTFINMLGGAWVSRLTTIGLFLVLIPVVL
TAVAGWHWFAIATYHANWNTSTTTDSHAIVKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTALAGIIYIAATQ
VIAGMFPASVMASSGAPFAISTSTILGGWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKIYGEMDKNGIPK
KGLLLAAVKMTALMILITIMNSSGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGFNIRNSVSLICSVLGCAFCFIA
LMGASSFELSGTFIVSLIILMFYGRKMHQRQNNDSDNNTAEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 2e-180 90
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 1e-180 90
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 2e-143 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB NP_804174.1 lysine/cadaverine antiporter VFG1671 Protein 1e-143 68