Gene Information

Name : thyA (t2910)
Accession : NP_806604.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3000160 - 3000954 bp
Length : 795 bp
Strand : -
Note : 'ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived'

DNA sequence :
ATGAAACAGTATTTAGAACTGATACAAAAAGTGCTGGATGAAGGCACACAGAAAAACGACCGTACCGGCACCGGCACGCT
TTCCATTTTTGGCCATCAGATGCGTTTTAACCTGCTGGAAGGCTTTCCTCTGGTGACGACGAAACGCTGCCATTTACGTT
CAATTATTCACGAACTGCTATGGTTTTTGCAGGGCGATACCAACATCGCTTACCTACACGAAAATAATGTCACCATCTGG
GACGAATGGGCCGATGAGAACGGCGATTTAGGCCCGGTTTATGGTAAGCAGTGGCGTGCATGGCCAACACCGGATGGCCG
CCATATCGATCAGATCGCCACGGTCTTGAGCCAGCTTAAAAACGACCCGGACTCTCGTCGTATTATCGTTTCTGCGTGGA
ACGTCGGCGAGCTGGATAAGATGGCGCTGGCGCCGTGTCACGCCTTTTTCCAGTTTTATGTCGCAGATGGAAAACTCTCC
TGTCAGCTTTATCAGCGCTCCTGCGATGTGTTCCTCGGTCTGCCGTTCAACATTGCCAGCTACGCGTTACTGGTGCATAT
GATGGCGCAACAGTGCGACCTGGACGTCGGCGATTTTGTCTGGACCGGCGGCGACACGCACCTGTACAGCAACCATATGG
AGCAGACGCACCTGCAATTAAGCCGTGAACCGCGCGCGCTGCCGAAATTGGTCATTAAGCGTAAACCCGATTCGCTTTTT
GACTACCGGTTCGATGATTTCGAAATTGAAGGCTATGATCCGCACCCCGGTATTAAAGCGCCGGTCGCTATCTAA

Protein sequence :
MKQYLELIQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLLEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIW
DEWADENGDLGPVYGKQWRAWPTPDGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVGDFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSLF
DYRFDDFEIEGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-88 66