Gene Information

Name : stpA (t2780)
Accession : NP_806481.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Virulence
Product : tyrosine phosphatase
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2453
EC number : -
Position : 2859938 - 2861569 bp
Length : 1632 bp
Strand : -
Note : associated with virulence; corresponds to STY3001 from Accession AL513382: Salmonella typhi CT18

DNA sequence :
ATGCTAAGGTATGATGAGAGGAAGTTGAATAATTTAACATTGTCTTCATTTTCAAAATCTGGCGTGTCGAGTGATACCCG
GCTATATATTGCTAAGGAAAATACTGATAAGGCATATGTTGCGCCTGAAAAATTTTCGTCAAAAGTATTAACCTGGCTTG
GAAAAATGCCCTTATTTAAAAACACTGAAGTGGTGCAAAAACACACGGAAAATATCAGAGTACAGAACCAAAAGATTTTA
CAGACATTTCTCCAGGCATTAACGGAAAAATATGGGGAAAAAGCGGTCAATAATGCTTTGTACATGTCCAGTATAAATAT
GAACAAACCCCTTACCCAACGTTTAGTAGTGCAGATCACGGAGTGTGTAAAAGGTGCTGACGGAGGGTTTATAAATCTTA
TTAAGAACAAGGATAATGTTGGTGTCATGAATGCCGCTTTAGTCATAAAAGGCGGCGATACAAAAGTGACAGAACAAAAT
AACGATGTTGGTGCAGAAAGTAAGCAACCTTTACTCGATATCGCGCTAAAGGGACTTAAGAGAACAATACCGCAACTGGA
ACAAATGGATGGAAATAGCCTGCGAGAAAACTTCCAGGAGATGGCTTCAGGTAACGGCCCGCTGCGTTCATTAATGACGA
ATTTACAGAGTTTAAATAAAATTCCAGAGGCTAAACAACTTAATGATTATGTTACAACGTTAAAAAATATTCAGATAGGA
GCAGACAGGTTCTCACAATGGGGAACCTGTGGGGGAGAGGTTGAGAGGTGGATTGATAAAGCCTCTACTCATGAATTAAC
CCAAGCGGTAAAAAAAATTCACGTTATTGCTAAAGAACTGAAAAACGTTACAGCTGAACTTGAGAAAATAAAAGCCGGTG
CGTCAATGCCACAGACGATGAGCGGACCGACACTGGGCCTGGCACGGTTTGCGGTCAGCAGCATTCCCATTAATCAGCAA
ACCCAGGTGAAACTGAGCGATGGAATGCCTGTGCCAGTGAATACGTTAACTTTTGACGGTAAGCCTGTGGCATTAGCCGG
TTCGTGCCCAAAAAATACGCCGGATGCGCTGGAAGCGCATATGAAAATGCTTCTTGAAAAAGAATGTTCGTGCCTGGTGG
TGTTAACGTCGGAAGATCAGATGCAGGCAAAACAATTACCAGCCTATTTCAGAGGGAGCTACACCTTTGGCGAGGTGCAT
ACCAACAGCCAAAAAGTGAGCTCAGCCAGTCAGGGAGGAGCGATAGACCAATACAATATGCAACTGTCCTGCGGGGAAAA
GCGGTATACAATCCCGGTATTGCATGTGAAAAATTGGCCAGATCACCAGCCGTTACCGTCTACTGATCAGTTAGAATACC
TGGCGGATAGGGTGAAAAATAGTAACCAAAATGGCGCGCCGGGGCGTAGTTCATCAGATAAGCATTTACCGATGATTCAT
TGTCTGGGCGGAGTGGGAAGAACCGGAACGATGGCGGCGGCTCTTGTACTTAAGGATAATCCTCATAGTAATCTGGAGCA
GGTACGTGCAGATTTCCGGAATTCACGGAACAATAGAATGCTGGAAGACGCCTCACAGTTTGTACAACTAAAAGCAATGC
AAGCCCAGTTGCTTATGACGACGGCAAGCTGA

Protein sequence :
MLRYDERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEKFSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKIL
QTFLQALTEKYGEKAVNNALYMSSINMNKPLTQRLVVQITECVKGADGGFINLIKNKDNVGVMNAALVIKGGDTKVTEQN
NDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSLNKIPEAKQLNDYVTTLKNIQIG
ADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVIAKELKNVTAELEKIKAGASMPQTMSGPTLGLARFAVSSIPINQQ
TQVKLSDGMPVPVNTLTFDGKPVALAGSCPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPAYFRGSYTFGEVH
TNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADRVKNSNQNGAPGRSSSDKHLPMIH
CLGGVGRTGTMAAALVLKDNPHSNLEQVRADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
stpA NP_457272.1 tyrosine phosphatase (associated with virulence) Virulence SPI-1 Protein 0.0 100
stpA NP_806481.1 tyrosine phosphatase Virulence SPI-1 Protein 0.0 100
sptP NP_461799.1 protein tyrosine phosphatase/GTPase activating protein Virulence SPI-1 Protein 0.0 95
sptP YP_217797.1 protein tyrosine phosphate Not tested SPI-1 Protein 0.0 95

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
stpA NP_806481.1 tyrosine phosphatase VFG0540 Protein 0.0 95