Gene Information

Name : prgK (t2773)
Accession : NP_806474.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4669
EC number : -
Position : 2852867 - 2853625 bp
Length : 759 bp
Strand : -
Note : corresponds to STY2992 from Accession AL513382: Salmonella typhi CT18

DNA sequence :
ATGATTCGTCGATATCTATATACCTTTCTGCTGGTAATGACCCTTGCCGGCTGTAAGGATAAGGATCTTTTAAAAGGACT
GGACCAGGAACAGGCTAATGAGGTCATTGCCGTTCTGCAAATGCACAATATAGAGGCGAATAAAATTGATAGCGGAAAAT
TGGGCTATAGCATTACCGTTGCTGAGCCTGATTTTACCGCTGCGGTGTACTGGATTAAAACTTATCAGCTTCCTCCCCGG
CCACGGGTGGAAATAGCGCAGATGTTCCCGGCGGATTCGCTGGTATCGTCTCCGCGAGCTGAAAAGGCCAGGTTATATTC
GGCTATTGAACAGCGACTGGAACAGTCATTACAGACGATGGAGGGCGTGCTCTCCGCCAGGGTCCATATTAGTTATGATA
TTGATGCTGGTGAAAATGGCCGTCCGCCAAAACCTGTTCATCTGTCGGCATTAGCCGTATATGAACGAGGTTCGCCGCTT
GCGCATCAGATCAGCGATATCAAGCGTTTCTTAAAGAATAGTTTTGCCGATGTGGATTATGACAACATTTCTGTTGTGTT
GTCAGAACGTTCTGATGCCCAATTACAGGCTCCCGGCACACCAGTAAAACGTAATTCTTTTGCAACCAGTTGGATTGTGT
TGATTATTTTGTTATCCGTGATGTCAGCAGGCTCTGGCGTCTGGTATTACAAAAACCATTATGCCCGCAATAAGAAAGGC
ATAACGGCTGATGATAAGGCGAAATCGTCAAATGAATAG

Protein sequence :
MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNIEANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPR
PRVEIAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPL
AHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILLSVMSAGSGVWYYKNHYARNKKG
ITADDKAKSSNE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prgK NP_457265.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 6e-116 100
prgK NP_806474.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 6e-116 100
prgK YP_217790.1 cell invasion protein Virulence SPI-1 Protein 3e-115 99
prgK NP_461792.1 needle complex inner membrane lipoprotein Virulence SPI-1 Protein 3e-115 99
prgK AAS66872.1 PrgK Virulence SSR-2 Protein 4e-57 58
ECs3716 NP_311743.1 EprK Not tested LIM Protein 7e-55 56
eprK AAZ31284.1 EprK Virulence ETT2 Protein 8e-54 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
prgK NP_806474.1 pathogenicity island 1 effector protein VFG0533 Protein 1e-115 99
prgK NP_806474.1 pathogenicity island 1 effector protein VFG0998 Protein 6e-45 47
prgK NP_806474.1 pathogenicity island 1 effector protein VFG1787 Protein 2e-37 46