Gene Information

Name : ribD (t2447)
Accession : NP_806177.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 1.1.1.193
Position : 2517945 - 2519048 bp
Length : 1104 bp
Strand : -
Note : 'riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine

DNA sequence :
ATGCAGGATGAGTTTTACATGGCGCGAGCGCTCAAACTGGCGCAGCGTGGACGTTTCACCACTCACCCGAACCCTAATGT
CGGCTGTGTCATTGTTAACAATGGCGACATCGTCGGCGAAGGTTATCACCATCGCGCCGGAGAGCCGCACGCCGAGGTCC
ATGCGCTGCGGATGGCGGGCGCAAAAGCCAAAGGCGCAACCGCCTATGTCACGCTTGAACCCTGTAGCCATCATGGGCGA
ACGCCGCCATGTTGCGATGCGCTGATTGCGGCTGGCGTCGCGCGCGTGGTCGCCGCGATGCAGGACCCGAACCCACAGGT
CGCCGGGCGCGGGCTGTATCGCCTGCAACAGGCGGGTATTGCGGTCAGCCACGGGTTAATGATGAGTGAAGCGGAGGCGC
TCAATAAAGGCTTCCTCAAACGGATGCGTACCGGATTCCCTTATCTTCAGCTTAAACTGGGTGCCTCCGTGGATGGACGG
ACGGCGATGGCCAGCGGCGAAAGCCAGTGGATCACCTCGCCGCAGGCCCGGCGCGACGTTCAGCGCTTGCGTGCGCAAAG
CCACGCTATTTTAACCAGTAGCGCGACGGTATTGGCTGACGATCCGGCCTTGACGGTGCGTTGGGCGGAGTTAGACGCCT
CTACACAGGCGTCTTACCCGCAGGAAAATCTGCGCCAGCCGGTGCGAATTGTTATCGACAGCCAAAACCGGGTAACGCCT
GCGCATCGTATTGTGCAGCAGCCTGGCGAAACGTGGATTGCGCGTACCCAGGAAGATAGCCACGCGTGGCCCGATTCGGT
TCGTACTATCAGCGTGCCGGCGCACAACGGACATTTGGATCTGGTTGTGCTGATGATGCAGTTAGGCAGGCAGCAGATTA
ATAGCATATGGGTTGAGGCCGGACCGGGACTGGCGGGCGCGTTGCTGCAAGCCGGGCTGGTGGATGAACTGATTGTCTAT
GTCGCGCCTAAATTGTTGGGAACCCAGGCGCGGGGATTATGCGAATTGCCGGGGCTTGAGAAGCTCGCCGACGCGCCGCA
ATTTACCTTCAGCGAAATACGTCATGTCGGCCCGGATGTTTGCCTGCATATGGTGAGCGCATGA

Protein sequence :
MQDEFYMARALKLAQRGRFTTHPNPNVGCVIVNNGDIVGEGYHHRAGEPHAEVHALRMAGAKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVAAMQDPNPQVAGRGLYRLQQAGIAVSHGLMMSEAEALNKGFLKRMRTGFPYLQLKLGASVDGR
TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWAELDASTQASYPQENLRQPVRIVIDSQNRVTP
AHRIVQQPGETWIARTQEDSHAWPDSVRTISVPAHNGHLDLVVLMMQLGRQQINSIWVEAGPGLAGALLQAGLVDELIVY
VAPKLLGTQARGLCELPGLEKLADAPQFTFSEIRHVGPDVCLHMVSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 2e-57 45
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 2e-57 45