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Name : leuS (t2219) Accession : NP_805962.1 Strain : Salmonella enterica Ty2 Genome accession: NC_004631 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 2284615 - 2287197 bp Length : 2583 bp Strand : + Note : 'leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucy DNA sequence : ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCACATTTGAAGTGAC CGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTGGCCGACTACACATGGGCCACGTAC GTAACTACACCATCGGCGACGTGGTTGCCCGCTACCAGCATATGCTGGGCAAAAACGTGCTGCAGCCAATCGGCTGGGAC GCCTTCGGCCTGCCGGCGGAAGGCGCGGCGGTGAAGAACAACACCGCGCCGGCGCCGTGGACGTACGACAACATCGCGTA CATGAAAAACCAGCTCAAAACGCTGGGTTTTGGCTATGACTGGAGCCGTGAAATCGCGACCTGCACCCCGGAATACTACC GTTGGGAACAGAAATTCTTCACCGAGCTGTATAAAAAAGGCCTGGTGTACAAGAAGACTTCTGCCGTTAACTGGTGCCCG AACGATCAGACCGTTCTCGCCAACGAACAGGTGATCGACGGCTGCTGCTGGCGTTGCGACACCAAAGTTGAGCGTAAAGA GATCCCACAGTGGTTTATCAAAATCACCGCTTACGCAGACGAGCTGTTGCGCGATCTGGATAAGCTGGACCACTGGCCTG ATACCGTAAAAACGATGCAGCGCAACTGGATTGGCCGCTCTGAAGGCGTGGAAATCACCTTCGATGTGAAGGGTTACGAT AACACGCTGACCGTCTATACCACCCGTCCGGATACCTTTATGGGCGCCACCTACCTGGCAGTGGCCGCCGGTCATCCGCT GGCGCAAAAAGCGGCGGCGAACAACGCCGAGCTGGCGGCGTTCATCGACGAATGCCGTAACACCAAAGTGGCCGAAGCCG AAATGGCGACCATGGAGAAAAAAGGCGTCGACACCGGCTATAAAGCGATTCATCCGTTAACTGGCGAAGAGATCCCGGTC TGGGCGGCAAACTTTGTCCTGATGGAGTACGGCACTGGCGCGGTGATGGCCGTTCCGGGTCACGATCAGCGCGACTACGA ATTTGCCTCCAAATACGGTTTGACCATCAAGCCGGTGATTCTGGCCGCTGACGGTTCCGAGCCGGATCTTTCCGAACAGG CGCTGACCGAAAAAGGCGTGCTGTTTAACTCCGGTGAGTTCGACGGTCTGGCCTTTGAAGCGGCGTTTAACGCCATTGCC GATAAACTGGCGGAAAAAGGCGTCGGCGAACGTAAAGTGAACTACCGTCTGCGTGACTGGGGCGTTTCCCGTCAGCGTTA CTGGGGCGCGCCGATCCCGATGGTCACCCTGGAAGACGGCACCGTGCTGCCGACGCCGGAAGATCAACTGCCGGTTATTT TGCCGGAAGACGTCGTCATGGACGGCATCACCAGCCCGATCAAGGCCGATCCTGAGTGGGCGAAAACCACCGTTAACGGT ATGCCGGCGCTGCGTGAAACCGACACCTTCGACACCTTTATGGAATCGTCATGGTACTACGCGCGTTACACCTGCCCGCA GTATCAGGAAGGAATGCTGGATTCGAAAGCGGCAAACTACTGGCTGCCAGTCGACATCTACATCGGCGGTATTGAACATG CCATCATGCACCTGCTCTACTTCCGCTTCTTCCATAAGCTGATGCGCGATGCGGGCATGGTCACCTCTGACGAGCCGGCT AAACAGTTGCTGTGCCAGGGCATGGTACTGGCGGATGCGTTCTATTATGTCGGCGAGAACGGCGAGCGTAACTGGGTTTC GCCAGTTGACGCTATCGTCGAGCGCGATGAAAAAGGCCGCATCGTCAAAGCAAAAGACGCAGCGGGTCATGAGCTGGTCT ACACTGGCATGAGTAAAATGTCCAAGTCGAAAAATAACGGTATCGACCCGCAGGTAATGGTTGAACGTTATGGCGCGGAT ACGGTACGCCTGTTTATGATGTTCGCTTCTCCGGCGGATATGACTCTGGAATGGCAGGAGTCCGGCGTAGAAGGCGCAAA CCGCTTTATTAAACGCGTCTGGAAGCTGGTTTACGAACACACCGCTAAAGGTCCTGTCGCGGCGCTGAACGTCGATGCGC TGAGCGAAGATCAAAAAGCGCTGCGTCGCGATGTGCATAAAACCATTGCCAAAGTGACCGATGATATCGGCCGCCGTCAG ACGTTCAACACCGCCATTGCGGCGATCATGGAGTTGATGAACAAACTGGCGAAAGCCCCGCAGGAAGGCGAACAAGACCG CGCACTGCTTCAGGAAGCGCTGCAGGCCGTCGTGCGTATGCTTAACCCGTTCACCCCGCACGTCTGCTTTACCTTGTGGC AGGAACTGGGTGGCGAAGGCGATATCGACAACGCGCCGTGGCCGGTTGCCGACGAGCAGGCAATGGTGGAAAACACCACG CTGGTTGTCGTGCAGGTTAACGGTAAAGTTCGCGGTAAGATCACCGTTGCGGTGGATGCCACCGAAGAACAGGTGCGTGA ACGTGCAGGCCAGGAACATCTGGTGGCAAAATATCTTGATGGCGTTACCGTGCGTAAAGTGATTTACGTTCCGGGTAAAC TCCTCAATCTGGTTGTTGGCTAA Protein sequence : MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQHMLGKNVLQPIGWD AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYD NTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPV WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIA DKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG MPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPA KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD TVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQ TFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTT LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-151 | 42 |
