Gene Information

Name : copR (t1823)
Accession : NP_805595.2
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Virulence
Product : transcriptional regulator YedW
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1886040 - 1886720 bp
Length : 681 bp
Strand : +
Note : induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistanc

DNA sequence : 
ATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGT
TGATTATGCCTGTGATGGACGAGACGGATTACACCTAGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGC
TGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCTGTTATTTGCCTGACGGCGCGC
GACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACT
GCTGGCCCGGGTGAGAGCTCAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGATG
CCACAAAGCAATCGGTGTTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTGGCG
TCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCCAGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACAC
CGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGGA
TGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAA

Protein sequence : 
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAYQPPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRLQAETSQNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 7e-101 98
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 5e-100 97

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR NP_805595.2 transcriptional regulator YedW BAC0083 Protein 5e-55 58
copR NP_805595.2 transcriptional regulator YedW BAC0197 Protein 2e-57 57
copR NP_805595.2 transcriptional regulator YedW BAC0125 Protein 5e-59 56
copR NP_805595.2 transcriptional regulator YedW BAC0638 Protein 1e-51 56
copR NP_805595.2 transcriptional regulator YedW BAC0308 Protein 6e-53 55
copR NP_805595.2 transcriptional regulator YedW BAC0111 Protein 6e-55 53
copR NP_805595.2 transcriptional regulator YedW BAC0347 Protein 3e-48 51
copR NP_805595.2 transcriptional regulator YedW NC_010079.5776364.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW NC_002952.2859858.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW NC_007622.3794948.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW AE015929.1.gene1106. Protein 4e-32 44
copR NP_805595.2 transcriptional regulator YedW NC_003923.1003417.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW NC_013450.8614146.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW NC_002951.3238224.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW NC_007793.3914065.p0 Protein 4e-37 44
copR NP_805595.2 transcriptional regulator YedW NC_002758.1121390.p0 Protein 4e-37 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR NP_805595.2 transcriptional regulator YedW VFG0596 Protein 3e-101 98
copR NP_805595.2 transcriptional regulator YedW VFG0473 Protein 6e-30 42
copR NP_805595.2 transcriptional regulator YedW VFG1389 Protein 2e-30 42