Gene Information

Name : spiA (t1262)
Accession : NP_805065.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Virulence
Product : outer membrane secretory protein
Function : -
COG functional category : N : Cell motility
COG ID : COG1450
EC number : -
Position : 1334869 - 1336362 bp
Length : 1494 bp
Strand : +
Note : corresponds to STY1726 from Accession AL513382: Salmonella typhi CT18

DNA sequence :
ATGGTAGTAAATAAACGTTTAATCTTAATTTTACTATTTATACTCAATACAGCAAAGAGTGATGAGTTATCATGGAAAGG
TAATGACTTCACCCTTTATGCCAGACAAATGCCATTAGCAGAGGTTTTACATCTGCTCTCAGAGAACTATGATACGGCTA
TTACTATTAGCCCATTGATAACAGCTACATTTAGTGGAAAAATTCCGCCTGGACCACCGGTCGATATTTTGAATAACCTG
GCAGCACAATATGATTTGCTAACCTGGTTTGATGGCAGCATGTTATATGTATATCCTGCATCGTTATTAAAACATCAGGT
TATCACTTTCAATATTTTATCTACTGGACGGTTCATTCATTACTTACGCAGCCAGAATATCCTTTCATCACCGGGATGCG
AGGTTAAAGAAATTACCGGTACCAGAGCTGTGGAGGTGAGTGGTGTTCCCAGCTGTCTGACTCGTATTAGTCAATTAGCT
TCAGTGCTGGATAATGCGTTAATCAAACGAAAAGACAGTGCGGTGAGTGTAAGTATATACACGCTTAAGTATGCCACTGC
GATGGATACCCAATACCAATATCGCGATCAGTCCGTCGTGGTTCCAGGGGTCGTGAGTGTATTGCGTGAGATGAGTAAAA
CCAGCGTACCGGCGTCATCGACGACCAATGGTTCACCCGCTACACAGGCATTGCCCATGTTTGCTGCCGACCCACGCCAG
AATGCAGTGATCGTTCGTGATTATGCGGCCAATATGGCCGGGTATCGGAAACTCATCACAGAATTAGATCAACGCCAGCA
GATGATAGAGATTTCGGTGAAAATTATCGATGTTAATGCTGGAGATATTAACCAGTTAGGCATCGACTGGGGAACGGCAG
TGTCGCTGGGTGGCAAGAAAATTGCGTTCAATACAGGTTTGAATGACGGTGGTGCTAGCGGTTTTTCAACGGTAATCAGC
GATACCTCAAACTTTATGGTGCGTTTGAATGCCCTGGAAAAAAGCTCTCAGGCTTATGTACTTTCCCAGCCATCTGTGGT
GACTTTAAATAATATCCAGGCTGTGCTGGATAAAAATATTACTTTCTATACCAAACTGCAGGGAGAAAAAGTGGCTAAAC
TTGAATCCATCACTACGGGTTCTTTGTTGCGCGTTACACCTCGCTTGTTAAATGACAATGGCACGCAAAAAATAATGCTT
AATCTTAATATTCAGGATGGACAACAAAGTGATACGCAAAGCGAAACAGATCCGCTACCCGAAGTGCAAAATTCTGAAAT
TGCTTCGCAAGCCACATTATTGGCCGGACAAAGTCTATTGCTGGGAGGGTTTAAACAAGGTAAACAAATCCACTCGCAAA
ACAAAATCCCTTTATTGGGCGATATCCCTGTCGTAGGTCATTTGTTTCGCAATGATACGACTCAAGTACATAGTGTAATC
AGGCTTTTTTTGATTAAAGCCTCAGTAGTAAATAATGGCATATCTCATGGTTAA

Protein sequence :
MVVNKRLILILLFILNTAKSDELSWKGNDFTLYARQMPLAEVLHLLSENYDTAITISPLITATFSGKIPPGPPVDILNNL
AAQYDLLTWFDGSMLYVYPASLLKHQVITFNILSTGRFIHYLRSQNILSSPGCEVKEITGTRAVEVSGVPSCLTRISQLA
SVLDNALIKRKDSAVSVSIYTLKYATAMDTQYQYRDQSVVVPGVVSVLREMSKTSVPASSTTNGSPATQALPMFAADPRQ
NAVIVRDYAANMAGYRKLITELDQRQQMIEISVKIIDVNAGDINQLGIDWGTAVSLGGKKIAFNTGLNDGGASGFSTVIS
DTSNFMVRLNALEKSSQAYVLSQPSVVTLNNIQAVLDKNITFYTKLQGEKVAKLESITTGSLLRVTPRLLNDNGTQKIML
NLNIQDGQQSDTQSETDPLPEVQNSEIASQATLLAGQSLLLGGFKQGKQIHSQNKIPLLGDIPVVGHLFRNDTTQVHSVI
RLFLIKASVVNNGISHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spiA NP_456134.1 putative outer membrane secretory protein Virulence SPI-2 Protein 0.0 100
spiA NP_805065.1 outer membrane secretory protein Virulence SPI-2 Protein 0.0 100
spiA AAC44301.1 SpiA Virulence SPI-2 Protein 0.0 99
ssaC NP_460359.1 outer membrane secretin precursor Virulence SPI-2 Protein 0.0 99
ssaC YP_216402.1 secretion system apparatus protein SsaC Virulence SPI-2 Protein 0.0 99
YPO0257 YP_002345337.1 type III secretion protein Virulence Not named Protein 1e-124 53
escC YP_003223482.1 T3SS structure protein EscC Virulence LEE Protein 4e-96 45
escC YP_003232146.1 T3SS structure protein EscC Virulence LEE Protein 4e-96 45
escC AAK26708.1 EscC Virulence LEE Protein 3e-96 45
escC AAL57535.1 EscC Virulence LEE Protein 3e-96 45
escC CAC81855.1 EscC protein Virulence LEE II Protein 3e-96 45
escC CAI43881.1 EscC protein Virulence LEE Protein 3e-96 45
escC AFO66299.1 putative type III complex subunit Virulence SESS LEE Protein 2e-100 44
escC AFO66408.1 putative type III complex subunit Virulence SESS LEE Protein 2e-100 44
unnamed AAL06362.1 EscC Virulence LEE Protein 2e-95 44
ECs4575 NP_312602.1 EscC Virulence LEE Protein 5e-95 44
escC AAC38377.1 EscC Virulence LEE Protein 4e-94 44
escC AAC31520.1 L0041 Virulence LEE Protein 4e-95 44
escC ACU09465.1 type III secretion outer membrane pore YscC/HrcC family Virulence LEE Protein 4e-95 44
escC YP_003236095.1 T3SS structure protein EscC Virulence LEE Protein 8e-95 44
escC NP_290275.1 hypothetical protein Virulence LEE Protein 5e-95 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spiA NP_805065.1 outer membrane secretory protein VFG0495 Protein 0.0 99
spiA NP_805065.1 outer membrane secretory protein VFG0723 Protein 2e-94 44
spiA NP_805065.1 outer membrane secretory protein VFG0819 Protein 2e-95 44