Gene Information

Name : cvrA; nhaP2; ycgO (t1076)
Accession : NP_804893.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1157987 - 1159720 bp
Length : 1734 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCTGCAACAATTATTAGTCTATTTATTTTAGGTTCCATCCTTGTAACCAGCAGTATCCTGTTAAGTTCATTCTC
ATCGCGACTGGGTATCCCGATTCTGGTCATTTTCCTCGCCATTGGGATGTTAGCGGGTGTGGATGGCATTGGCGGTATTC
CTTTCGATAATTATCCTTTCGCTTATATGGTCAGTAACCTGGCGCTGGCGATTATTTTACTCGATGGCGGCATGCGCACC
CAGGCCAGCTCTTTCCGGGTAGCGCTGGGCCCCGCGCTGTCGCTGGCGACGCTCGGCGTACTGATCACGTCGGGGTTAAC
AGGTATGATGGCCGCCTGGCTGTTTCATCTGGATCTTATCGAAGGTCTGCTTATCGGCGCGATAGTCGGTTCCACTGACG
CCGCAGCGGTCTTTTCTCTGCTTGGCGGCAAAGGGCTAAACGAACGTGTAGGCTCCACGCTGGAGATCGAATCGGGAAGT
AACGACCCGATGGCCGTTTTTTTGACCATTACATTAATTGAGATGATCCAGAAACATGAAACCGGCCTGGACTGGATGTT
TGCCGTCCATATTATCCAGCAGTTCGGTCTCGGTATTGTTTTTGGCCTCGGCGGCGGTTACCTGCTACAGCAGATGATCA
ACCGTATTTCTCTGCCCAGCGGCCTGTATCCGATGCTGGCGCTCAGCGGCGGTATTCTGATTTTTGCTTTGACGACCGCG
CTTGAAGGCAGCGGCATTCTCGCGGTCTATCTGTGCGGATTCCTGTTAGGAAACCGTCCGATTCGCAACCGTTACGGCAT
CCTGCAAAACTTTGACGGACTGGCCTGGCTGGCGCAGATCGCCATGTTCCTGGTCCTGGGACTGCTGGTGACGCCTTCCG
ATCTGTGGCCGATTGCCGTCCCTGCGCTTATTCTCTCTATCTGGATGATTTTCTTCGCCCGCCCATTGTCGGTATTTACC
GGCCTGCTGCCTTTTCGCGGCTTCAATCTTCGGGAGCGCATTTTCATCAGTTGGGTCGGACTGCGCGGCGCGGTGCCGAT
TATTCTCGCCGTTTTCCCGATGATGGCCGGGCTTGAAAACGCTCGCCTGTTCTTTAATGTCGCTTTCTTTGTGGTACTGG
TGTCGCTGCTCCTGCAGGGAACATCGCTGTCATGGGCGGCGAAGAGAGCCAAAGTGGTCGTGCCTCCGGTTGGCTGGCCA
GTATCGCGCGTGGGGCTTGACATCCATCCTGATAATCCGTGGGAACAATTCATCTATCAGTTGAGCGCCGACAAATGGTG
CGTCGGCGCGGCGTTGCGCGACCTGCATATGCCGAACGAAACCCGCATTGCCGCGCTATTTCGCAATAATGAACTGTTTC
ACCCCACGGGTAGCACTCGCCTGCAGGAAGGCGACGTACTCTGCGTGATTGGCCGGGAGCGCGATCTGCCAGCGCTGGGC
AAATTGTTTAGCCAGTCGCCGCCGGTTTCGTTAGATCAGCGTTTCTTTGGCGATTTTATCCTCGAAGCGAACGCGAAATT
CGCCGACGTGGCGCTTATCTACGGGCTGGAAGAAGGAACGGAATACCGGGATAAACAACAAACCCTCGGTGAAATCATAC
AGCAGCTGCTGGGCGCTGCGCCGGTCGTTGGCGATCAGGTGGAGTTTGGCGGCATGATTTGGACGGTAGCTGAAAAAGAA
GATAACGTGGTACGCAAGATTGGGGTACGCGTCGCCGAAGACGAAGCAGAATAA

Protein sequence :
MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRT
QASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFT
GLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWP
VSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALG
KLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKE
DNVVRKIGVRVAEDEAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 92
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 92