Gene Information

Name : SPs0422 (SPs0422)
Accession : NP_801684.1
Strain : Streptococcus pyogenes SSI-1
Genome accession: NC_004606
Putative virulence/resistance : Unknown
Product : DNA polymerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : -
Position : 453718 - 455640 bp
Length : 1923 bp
Strand : +
Note : similar to GB:AAL82293.1 (AF424782) percent identity 55 in 654 aa

DNA sequence :
ATGAGACATTTAAATATTGATATTGAAACCTATAGTTCGAATGACATCAAAAATGGGGTTTACAAGTACGCTGACGCAGA
AGATTTTGAGATTTTACTTTTCGCTTACTCTATAGATGGCGGAGAAGTAGAGTGCCTTGATTTGACAAGGCAGTCTCTAC
CTGAAGACATCAAAGATATGTTATTTGATGATAAAGTCCGAAAGCACGCCTTTAATGCCCAATTCGAAAGAGTTTGCCTC
AGTCGTTACCTCGGCCTACCTTACTATCTAGATCCTTGCCAATGGCAATGCACCATGGTGCTGGCCCAAGAGTTGGGTCT
GCCTTCAAGCTTGGAAAAGTGTGCGCTGTATTTAAAATTAGCGCAGGAAAAAGATACCTCGGGTAAAAACTTAATCAGAT
ACTTTTCCCTGCCTTGCAAACCAAGTAAAACTAACGGTGGGAGAACTAGAAATTTACCAGAACACGCCCCCGAAAAGTGG
CAAATGTTTATTGACTACTGCATCCAAGACGTTGTTGTTGAGATGGCAATCGCCGAAAAACTAGAGTCAGTTCCTGTGCA
CGACCGTGAATGGGATTACTACGCCTGTGACCAGAGAATCAACGACAGAGGCGTGGCGCTTGATAAAGAGTTAGTTGCTT
CGGCCTTGTATTGTAAAGATGTTAAGATGGAAAGTTTGTCTGGGGAACTAAAAGCTCTAACAGGACTTGATAATCCTAAT
AGCAGGACGCAGTTGCTACCGTGGCTAAAAGAACATGGCTATTCGGCTAGTGGGCTGACTAAAGCAGATGTTGAGAAGGA
GCTTAAGACGGCCGAAGGAGAACTTAAGAGAGTTTTAGAACTTAAACTACAAACCGCTATGTCAAGTCTAAAAAAATATG
AAGCTATGGAAAGAGCTAGGTGCTCAGACGGACGAGTTCATGGGCTACTTCAGTTTTACGGGGCTAGCCGGACAGGAAGA
TGGGCGGGCAGAGTTGTCCAAGTACAGAACTTAGCTAGGAATTATATAAAGGATCTAGATGATGCTAGAGAGTATGTTAA
AAAGCGTGACATTGATGCTGTGGAGATTTTATACGATAGCCTTAATGACACTTTAAAGCAGCTCGTGCGAACGGCCCTCG
TGGCTAAAGATGGCTGTACCTTCTATGTCTCTGACTTCTCGGCGATTGAGGCTAGGGTGATTGCGTGGTTTGCTGGAGAG
CAGTGGAGGCTTGACGTGTTTTCGACGCACGGGAAAATCTACGAGGCGTCTGCCAGTCAGATGTTCGGAATTCCAATTGA
GGAGATTGACAAGGAACTACGCCAAAAGGGCAAAATTTCAGAGTTAGCACTTGGCTATCAAGGGGGTCCTGGAGCGCTTA
AGCAGATGGGGGCTCTAAACATGGGAGTCAAAGAAGAAGAGCTTCAAGGGTTAGTTGATGACTGGCGCAGGGCCAATAAG
AAAATCGTCCAATTTTGGAAAGACGTACAAAGAGCCGCCATCAAAGCCATCAAATCGAGAGCACCTGTAAGACTTGGGAA
GCTACGATTTAGATACCGTAAAGGTTTCCTCTTTATAACATTGCCTAGCGGTAGGAACTTAGCTTATGCAAGAGCCAAGG
TTGAGCCGGGCGACTATGGAGACAAAATCGTCTATGAGGGCCAAGGAGATAAGGCCTACTTCACAGCGCAAGAGACTTAC
GGAGGTAAGCTTGTCGAAAATATCGTTCAGGCGACAGCTAGGGATATTCTAGCCGAAGCGCTTCTGAGAATTGAAGCTGC
CGGCCATGGTGTTGTTTTCCACGTTCATGACGAGGCTATTATCGAAGGCTCAGGCCTGACAATCGAAGAGGTTAATGATT
TGATGGCTCAGGCCCCTGAATGGGCGGAGGGTCTTCCTTTAAATAGCGAAGGCTACATAACAAAGTATTATATGAAGGAT
TAG

Protein sequence :
MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVECLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCL
SRYLGLPYYLDPCQWQCTMVLAQELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYCKDVKMESLSGELKALTGLDNPN
SRTQLLPWLKEHGYSASGLTKADVEKELKTAEGELKRVLELKLQTAMSSLKKYEAMERARCSDGRVHGLLQFYGASRTGR
WAGRVVQVQNLARNYIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEARVIAWFAGE
QWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGPGALKQMGALNMGVKEEELQGLVDDWRRANK
KIVQFWKDVQRAAIKAIKSRAPVRLGKLRFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIVYEGQGDKAYFTAQETY
GGKLVENIVQATARDILAEALLRIEAAGHGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEGLPLNSEGYITKYYMKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 0.0 99
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 3e-156 55
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 4e-157 55