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Name : SPs0350 (SPs0350) Accession : NP_801612.1 Strain : Streptococcus pyogenes SSI-1 Genome accession: NC_004606 Putative virulence/resistance : Unknown Product : seryl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0172 EC number : 6.1.1.11 Position : 387176 - 388453 bp Length : 1278 bp Strand : - Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGCTAGATCTTAAACGTATCCGTACCGATTTTGACACTGTCGCTGCCAAATTAAAAAACCGTGGTGTTTCTGAAGACAC CCTGACCCATCTTAAAGAACTTGATGAAAAACGTCGTACTCTATTAGTGCAATCAGAAGAATTAAAAGCAGGGCGTAATA TTGCTTCTGCTGCCATCGCTCAAGCAAAACGTCAAAAAGAAGATGCCACTCAACAAATTGCTGATATGCAAAAAGTCTCT GCAGATATCAAAACTATTGACAATCAACTAGTAGCTATCGACCAGCAAGTTGCTGACATCATCACTGTTTTACCTAATAC TCCTCACGATTCTGTCCCTGTTGGAGCTGACGAAGAAGACAATGTCGAGATTCGCCGTTGGGGAACGCCTCGTGACTTTG ACTTCGAAGTTAAGGCTCATTGGGATCTAGGCGAAGATCTTGATATTTTAGACTGGGAACGTGGGGCAAAGGTAACTGGT GCTCGTTTCTTATTCTATAAAAATCTTGGTGCTCGTTTGGAGCGTGCTCTTTATAACTTCATGCTGGATGAACATATCAA AGAAGGTTATCAAGAAATCATCACACCTTACATGGTTAACCACGATTCCATGTTTGGTACAGGACAATATCCAAAGTTCA AAGAGGACACCTTTGAATTAGCAGATACCAACTTTGTCCTGATTCCAACTGCTGAAGTGCCTTTGACCAATTATTACCGT GGGGAAATCCTAGACGGCAAAGAATTGCCAATTTACTTTACTGCAATGAGCCCATCTTTTCGTTCTGAAGCGGGTTCTGC GGGTCGTGACACACGTGGCCTTATCCGCCTACACCAATTCCACAAAGTTGAAATGGTTAAATTTGCTAAACCAGAAGAAT CTTACCAAGAACTAGAAAAAATGACTGCTAATGCTGAAAATATTCTTCAAAAACTTGGTTTGCCATATCGCGTCATTTCC CTTTGTACTGGAGACATGGGCTTCTCAGCTGCTAAAACCTATGACCTTGAAGTCTGGATTCCTGCACAAAACACCTACCG TGAAATTTCATCATGTTCAAATACTGAAGATTTCCAAGCACGACGTGCTCAAATCCGTTACCGTGATGAAGCTGACGGTA AGGTCAAACTTCTTCACACCCTTAATGGGTCAGGACTTGCTGTCGGTCGTACCGTAGCAGCCATTTTAGAAAACTACCAA AATGAAGATGGTTCTGTTACCATCCCTGAAGTACTCCGCCCTTACATGGGTGGCGAAACCGTCATTTCACCTAAATAA Protein sequence : MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQSEELKAGRNIASAAIAQAKRQKEDATQQIADMQKVS ADIKTIDNQLVAIDQQVADIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELADTNFVLIPTAEVPLTNYYR GEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVIS LCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQ NEDGSVTIPEVLRPYMGGETVISPK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| serS | YP_003446791.1 | seryl-tRNA synthetase | Not tested | The aminoglycoside resistance gene cluster | Protein | 5e-176 | 83 |
