Gene Information

Name : SPs0132 (SPs0132)
Accession : NP_801394.1
Strain : Streptococcus pyogenes SSI-1
Genome accession: NC_004606
Putative virulence/resistance : Virulence
Product : streptolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 147151 - 148875 bp
Length : 1725 bp
Strand : +
Note : similar to GB:AAL96968.1 (AE009966) percent identity 99 in 574 aa

DNA sequence :
ATGAAGGACATGTCTAATAAAAAAACATTTAAAAAATACAGTCGCGTCGCTGGGCTACTGACGGCAGCTCTTATCATTGG
TAACCTTGTTACTGCTAATGCTGAATCGAACAAACAAAACACTGCTAGTACAGAAACCACAACGACAAATGAGCAACCAA
AGCCAGAAAGTAGTGAGCTAACTACTGAAAAAGCAGGTCAGAAAACGGATGATATGCTTAACTCTAACGATATGATTAAG
CTTGCTCCCAAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAAGTCAGAAGACAAAAAAAAGAGCGAAGAAGA
TCACACTGAAGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCA
TTGAAAATTTTGTTCCTAAAGAAGGCGTTAAGAAAGCTGATAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAAC
ACTACACCAGTCGATATTTCCATCATTGACTCTGTCACTGATAGGACCTATCCAGCAGCCCTTCAGCTGGCTAATAAAGG
TTTTACCGAAAACAAACCAGACGCGGTAGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAG
ACAAAGCAACGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTGTTAACCAATGGCAT
GATAATTATTCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAGTCACAGATTGA
AGCAGCTCTAAATGTTAATAGCAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGA
AGGTGATGATTGCAGCATACAAGCAAATTTTTTACACCGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGAT
AAATCAGTGACCTTTAAAGAGTTGCAACGAAAAGGTGTCAGCAATGAAGCTCCGCCACTCTTTGTGAGTAACGTAGCCTA
TGGTCGAACTGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAG
GAACAGATGTTAAAACTAATGGAAAATACTCTGATATCTTAGAAAATAGCTCATTTACAGCTGTCGTTTTAGGAGGAGAT
GCTGCAGAGCACAATAAGGTAGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAAGACAATGCTACCTTCAGTAG
AAAAAACCCAGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAACAGAACTG
AATACGTTGAAACAACATCTACCGAGTACACTAGTGGAAAAATTAACCTGTCTCATCAAGGCGCGTATGTTGCTCAATAT
GAAATCCTTTGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGTTGGGATAACAACTGGTA
TAGTAAGACATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATACGTATCATGGCTAGAGAGTGCA
CCGGCTTAGCTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATCAATGTCAACATC
TCAGGATCAACCCTGAGCCCATATGGTTCGATTACTTATAAGTAG

Protein sequence :
MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTTEKAGQKTDDMLNSNDMIK
LAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNIN
TTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH
DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFD
KSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGD
AAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHQGAYVAQY
EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNI
SGSTLSPYGSITYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 0.0 99
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 8e-93 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPs0132 NP_801394.1 streptolysin O VFG0976 Protein 0.0 100
SPs0132 NP_801394.1 streptolysin O VFG2275 Protein 3e-150 67
SPs0132 NP_801394.1 streptolysin O VFG1363 Protein 2e-91 43
SPs0132 NP_801394.1 streptolysin O VFG0074 Protein 5e-93 42