Gene Information

Name : VPA1113 (VPA1113)
Accession : NP_800623.1
Strain :
Genome accession: NC_004605
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 1174493 - 1175953 bp
Length : 1461 bp
Strand : -
Note : catalyzes the formation of betaine from betaine aldehyde

DNA sequence : 
ATGGAAATGAAAACACATTACATCGATGGTGCAATGTATATCGGATGTTCTGAAGAGCATTTCACCACTTACAATCCGGC
AAATGGTGAGCCATTGGCCAATATTAAACAAGCAAACCAGAGCGATATGGAAGCCGCTATTGAATCTGCAAAGCGCGGCT
TTGAGGTTTGGTCTGCAATGACGGCCATTGAACGTAGCCGGATTCTTAATAAAGCGGTAGCGATTCTGCGTGAACGCAAT
GACGAGTTAGCCGCTTTAGAAGTGGCGGACACGGGTAAGCCAATTCAAGAAGCGATCGCTGTTGATATTACGACAGGCGC
AGATGTTATCGAATATTACGCTGGTCTTGCACCAAGTTTGCAGGGTGAGCAACAACCACTTAATGAAAACCAGTTTTTCT
ATACCCGCCGTGAACCTTTGGGAATTTGCGCAGGTATTGGCGCCTGGAACTATCCTATTCAAATCGCAATGTGGAAATCA
GCACCAGCACTGGCTGCGGGTAATGCAATGATCTTTAAGCCGTCGGAAGAAACACCGCTTACAGCACTTAAGCTTGCGGA
AATTTATTCTGAAGCGGGCCTTCCTGATGGTGTGTTTAACGTCGTGCAGGGTGATTACCGGGTAGGGCAGATGCTAACGG
CGCATCCGGATATTGCTAAAGTATCGTTCACTGGCGAATCAGGCACTGGCAAAGTTGTTATGGGTGACAGTGCAAAAACG
CTTAAGCAAGTCACAATGGAGTTAGGTGGTAAGTCACCACTGATCGTATTCGACGATGCGAAGCTGGACGATGCGGTATC
AGCAGCAATGGTTGCTAACTTTTACACTCAGGGTGAGGTATGTACCAACGGTACCCGTGTATTTGTCCATGAATCTATCT
ACGACGACTTTGTTGCACAGCTTAAAACTCGTACTGAGAAACTGGTTGTCGGAGACCCTCTTGATGAAAATACACAAATC
GGTGCCCTAATTTCAAAAGAACATGAAAGCAAAGTGCTGTCAGCGATTGAGAGCGCAAAAGCGAGCGGTGCCACTCTGCT
GACCGGCGGTTACAAAGTAACAGATAATGGTCTGCAAAATGGTAACTTCGTTGCTCCAACCGTATTTATCGACTGTGACG
ATAGCATGAGCCACGTACAGCAAGAGATCTTTGGTCCTGTAATGTCCGTGCTTAAATTTAGCGAAGAAGCTGAAGTTATC
GAGCGAGCTAACGATACGGACTATGGCTTGGCTGCTGGTGTCTTTACTCAGAACCTCTCTCGCGCTCATCGCGTAATTCA
TAAGATTCAGGCAGGTATCTGCTGGGTTAATGCATGGGGTGACTCTCCGGCAGAAATGCCAGTTGGTGGCTATAAGCAAT
CCGGTATTGGCCGTGAGAACGGCGTCGAAACACTGAAGCACTACACGCAAACTAAGAGCGTACTGGTTCAGCTTAGCGAC
TTCGAAAGCCCTTACGCCTAA

Protein sequence : 
MEMKTHYIDGAMYIGCSEEHFTTYNPANGEPLANIKQANQSDMEAAIESAKRGFEVWSAMTAIERSRILNKAVAILRERN
DELAALEVADTGKPIQEAIAVDITTGADVIEYYAGLAPSLQGEQQPLNENQFFYTRREPLGICAGIGAWNYPIQIAMWKS
APALAAGNAMIFKPSEETPLTALKLAEIYSEAGLPDGVFNVVQGDYRVGQMLTAHPDIAKVSFTGESGTGKVVMGDSAKT
LKQVTMELGGKSPLIVFDDAKLDDAVSAAMVANFYTQGEVCTNGTRVFVHESIYDDFVAQLKTRTEKLVVGDPLDENTQI
GALISKEHESKVLSAIESAKASGATLLTGGYKVTDNGLQNGNFVAPTVFIDCDDSMSHVQQEIFGPVMSVLKFSEEAEVI
ERANDTDYGLAAGVFTQNLSRAHRVIHKIQAGICWVNAWGDSPAEMPVGGYKQSGIGRENGVETLKHYTQTKSVLVQLSD
FESPYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 5e-80 41
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-76 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-76 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-76 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-76 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VPA1113 NP_800623.1 betaine aldehyde dehydrogenase VFG0082 Protein 6e-77 41