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Name : leuS (VP0727) Accession : NP_797106.1 Strain : Genome accession: NC_004603 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 761473 - 764046 bp Length : 2574 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAACAATACAATCCACAAGACATTGAACAGAAAGTTCAAAAGCACTGGGATGACAACAAGACCTTTGTTGTAAG TGAAGACCCAAATAAAGAAAAATTCTACTGTCTATCTATGTTCCCATACCCAAGTGGTCGACTGCACATGGGTCACGTGC GCAACTACACCATCGGTGACGTAGTATCTCGCTTCCAACGCCTACAAGGCAAAAACGTAATGCAACCAATTGGTTGGGAT GCGTTCGGTCTACCAGCAGAAAACGCAGCGGTGAAAAACAACACAGCTCCTGCGCCATGGACTTACGAAAACATCGAATA CATGAAAAACCAGCTTAAATTGCTAGGTTTTGGCTACGACTGGAATCGTGAATTCGCAACTTGTACGCCTGAGTACTACC GTTGGGAACAAGAGTTCTTCACTAAGCTTTACGAAAAAGGCCTAGTTTACAAGAAAACGTCTTCTGTTAACTGGTGTCCA AATGACCAAACCGTTCTTGCAAACGAACAGGTTGAAGACGGCTGCTGCTGGCGTTGTGACACTCCAGTAGAGCAAAAAGA GATCCCTCAGTGGTTCATCAAGATCACAGAATACGCGCAAGAGCTACTTGACGATCTAGACAAACTTGAAGGTTGGCCAG AAATGGTTAAGACCATGCAACGCAACTGGATTGGTCGCTCTGAAGGTGTGGAACTGAAGTTTGAAGTGAAAGGTCAACAA GACCTAGAAGTTTACACAACGCGTCCAGACACACTGATGGGTGTGACTTACGTAGGTATCGCAGCGGGTCACCCTCTAGC AACGCTAGCTGCAGAGAACAACCCAGAGCTTGCTGCATTCATCGAAGAATGTAAGAACACCAAAGTTGCTGAAGCTGAAC TGGCGACAATGGAGAAGAAAGGTATGGCAACTGGCCTTACTGCTATTCATCCATTGAACGGTCGTGAAGTACCAGTTTAC GTCGCAAACTTCGTATTGATGGACTACGGTACAGGTGCTGTAATGGCAGTACCTGCACACGACCAACGCGACTTCGAATT CGCAACTAAGTACGGTCTAGACATCATCCCAGTGATCAAACCAGCAGATGGTAGCGAGCTAGACATCTCTGAAGCGGCAT ACACAGAGAAAGGTGTATTGTTCGATTCAGGTGAGTTCGACGGCCTAGAATTCCAAGCGGCATTCGATGCAATCGCAGCG AAGCTAGAAGCGGAAGGTAAAGGCACTAAGACAGTTAACTTCCGTCTACGTGACTGGGGTGTATCTCGTCAACGTTACTG GGGTGCACCAATCCCAATGGTAACCACTGAAGACGGTGAAGTTCATCCAGTACCTGCTGACCAACTACCAGTGATTCTTC CAGAAGACGTGGTAATGGACGGCGTAACCAGCCCAATCAAAGCAGACAAAGAATGGGCGAAGACCACATTCAACGGCGAA CCGGCTCTACGTGAGACAGATACGTTCGATACGTTCATGGAATCTTCTTGGTACTACGCACGTTACTGTTCACCACAAGC TGACGATATCCTAGATCCAGAAAAAGCAAACTACTGGCTACCAGTAGACCAGTACATCGGTGGTATCGAGCACGCTTGTA TGCACCTACTGTACTCACGCTTCTTCCACAAATTGCTACGTGACGCGGGCTACGTAACGTCTGACGAGCCGTTCAAACAG CTACTATGTCAAGGCATGGTACTGGCTGACGCGTTCTACTTCGAGAACGAGAAAGGCGGTAAAGAGTGGGTCGCACCAAC AGATGTTGCTGTAGAACGTGACGGTAAAGGCCGCATCATCTCTGCTAAAGACAACGAAGGCCGTGATGTAACACACTCAG GCATGATCAAAATGTCTAAGTCTAAAAACAACGGTATCGACCCTCAAGAGATGGTAGACAAGTACGGTGCTGATACAGTG CGTCTATTCATGATGTTCGCATCTCCAGCAGACATGACGCTTGAGTGGCAAGAATCTGGCGTAGAAGGTGCAAACCGCTT CCTAAAACGTGTTTGGAAACTAGTGAAAGAACACGCAGAGAAAGGCGCAGCAGAAGCAGTGGATACAGCAGCACTTTCTG GTGAGCAAAAAGCACTTCGTCGTGACGTTCACAAAACTATCGCGAAAGTGACTGACGATATCGCTCGTCGTCAAACGTTC AACACAGCAATCGCAGCAATCATGGAACTGATGAACAAGCTAGCGAAAGCACCTCAAGAATCTGCACAAGATCGTGCAAT TCTTGATGAAGCGCTAAAAGCGGTTGTAACGATGCTTTACCCAATCACTCCGCACATTTCATACGAGCTATGGACTGCGC TTGGTGAGTCAGACATCGACAACGCAGCATGGCCAACGTTTGATGAGAAAGCGCTAGTTGAAGACGAAAAAACTATCGTT GTTCAAGTTAACGGTAAGCTACGTGCGAAGTTAACAGTAGCGGCAGACGCAACGAAAGAACAAGTTGAAGAGCTTGGTCT AAACGACGAAAACGTTACTAAGTTCACAGATGGCCTAACAATCCGTAAAGTAATTTACGTACCAGGTAAACTGCTGAACA TCGTTGCAAACTAA Protein sequence : MQEQYNPQDIEQKVQKHWDDNKTFVVSEDPNKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVSRFQRLQGKNVMQPIGWD AFGLPAENAAVKNNTAPAPWTYENIEYMKNQLKLLGFGYDWNREFATCTPEYYRWEQEFFTKLYEKGLVYKKTSSVNWCP NDQTVLANEQVEDGCCWRCDTPVEQKEIPQWFIKITEYAQELLDDLDKLEGWPEMVKTMQRNWIGRSEGVELKFEVKGQQ DLEVYTTRPDTLMGVTYVGIAAGHPLATLAAENNPELAAFIEECKNTKVAEAELATMEKKGMATGLTAIHPLNGREVPVY VANFVLMDYGTGAVMAVPAHDQRDFEFATKYGLDIIPVIKPADGSELDISEAAYTEKGVLFDSGEFDGLEFQAAFDAIAA KLEAEGKGTKTVNFRLRDWGVSRQRYWGAPIPMVTTEDGEVHPVPADQLPVILPEDVVMDGVTSPIKADKEWAKTTFNGE PALRETDTFDTFMESSWYYARYCSPQADDILDPEKANYWLPVDQYIGGIEHACMHLLYSRFFHKLLRDAGYVTSDEPFKQ LLCQGMVLADAFYFENEKGGKEWVAPTDVAVERDGKGRIISAKDNEGRDVTHSGMIKMSKSKNNGIDPQEMVDKYGADTV RLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVKEHAEKGAAEAVDTAALSGEQKALRRDVHKTIAKVTDDIARRQTF NTAIAAIMELMNKLAKAPQESAQDRAILDEALKAVVTMLYPITPHISYELWTALGESDIDNAAWPTFDEKALVEDEKTIV VQVNGKLRAKLTVAADATKEQVEELGLNDENVTKFTDGLTIRKVIYVPGKLLNIVAN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 5e-160 | 44 |
