Gene Information

Name : murD (VP0458)
Accession : NP_796837.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 459690 - 461003 bp
Length : 1314 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGAACGTTGGCAAAACATACATAACGTTGTCGTCGTAGGGCTCGGTATTACCGGGCTCTCTGTCGTTAAACACCTCCG
AAAAACTCAGCCGCAATTGACGGTTAAAGTTATTGATACGCGTGACAATCCGCCAGGTGCCGAGCGTCTGCCTGAACAGG
TTGAACTACACCGTGGTGGTTGGAATACCCAGTGGCTTGCCGAGGCGGACTTGGTGGTGACCAACCCTGGTATAGCGTTG
GCGACACCAGAGATACAAACGGTGCTAGCGAAAGGCACGCCTGTCGTGGGGGACATCGAGTTGTTTGCTTGGGCTGTGAA
TAAGCCAGTGGTGGCCATCACGGGTTCAAACGGCAAGAGCACGGTGACAGATTTAACTGGTGTGATGGCAAAAGCGGCAG
GATTGACGGTGGGTGTCGGCGGTAACATTGGCGTGCCTGCACTGGAGCTGCTTGAGCAAGATGCGGATTTGTATGTACTG
GAACTTTCAAGTTTTCAGTTGGAAACGACGTCGAGTTTGAAACTCAAAGCGGCGGCATTTCTTAACCTTTCCGAAGATCA
TATGGATCGCTACGAAGGTATGGCAGATTATCGCGCTGCTAAGTTGCGTATTTTTGATCATGCAGAGTTAGCCGTGGTTA
ACCGTGATGACCAAGAGACGTACCCAGAGGTTGAGATGCCTGTGGTCACGTTTGGCAGCGATGAGCAAGCTTACGGCCTT
GAAGTCGATGGTTCTCGCACATGGTTACTTGATCATGGTCAGCGCGTTATCGCCAGCGATGAATTGAAACTTGTCGGCAA
ACATAACTTAGCGAACGCTCTCGTCGTGTTGGCTCTGCTCAAAGCTGCAGGTGTTGATTACCACAACGCTTTGAATGCAC
TTAAAAATTACACTGGACTGACACACCGATGCCAGGTGGTTGCGGATAATCGTGGCGTAAAATGGGTGAATGACTCTAAA
GCAACTAATATCGCAAGCACTATGGCTGCGCTATCAGGATTAGAGTCGACCGGTAAACTTTATCTGCTCGTTGGTGGTGT
CGGTAAAGGCGCGGACTTCACGCCATTAAAACCGATCTTTGCAACGCTTAACCTACAACTGTGCTGTTTTGGTCTAGACG
GTGATGATTTTATGCCACTACATGAGTCAGCAATCCGTTTCAACACCATGGAAGATGTGATTCAACAAATATCTTCGCAG
TTAAAATCTGGTGATATGGTGATGCTGTCTCCCGCATGTGCTAGCTTTGATCAATTCGACAATTTTATGGCAAGAGGCGA
TGCATTTGCTGTTCTTGCTCAGAAATATGCATAA

Protein sequence :
MERWQNIHNVVVVGLGITGLSVVKHLRKTQPQLTVKVIDTRDNPPGAERLPEQVELHRGGWNTQWLAEADLVVTNPGIAL
ATPEIQTVLAKGTPVVGDIELFAWAVNKPVVAITGSNGKSTVTDLTGVMAKAAGLTVGVGGNIGVPALELLEQDADLYVL
ELSSFQLETTSSLKLKAAAFLNLSEDHMDRYEGMADYRAAKLRIFDHAELAVVNRDDQETYPEVEMPVVTFGSDEQAYGL
EVDGSRTWLLDHGQRVIASDELKLVGKHNLANALVVLALLKAAGVDYHNALNALKNYTGLTHRCQVVADNRGVKWVNDSK
ATNIASTMAALSGLESTGKLYLLVGGVGKGADFTPLKPIFATLNLQLCCFGLDGDDFMPLHESAIRFNTMEDVIQQISSQ
LKSGDMVMLSPACASFDQFDNFMARGDAFAVLAQKYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-60 42
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-60 42