Gene Information

Name : hemC (VP2988)
Accession : NP_799367.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3188037 - 3188975 bp
Length : 939 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGACCCAATCCACACCAATTCGCATTGCAACTCGAAAAAGCCCACTTGCACTATGGCAAGCTCATTTTGTTAAAGACGC
TCTTCAAGCCGCTCATCCTGGCTTGGAAGTCGAGTTGGTAACCATGGTGACCAAAGGTGACGTGATTTTGGATACACCGC
TGGCTAAAGTTGGTGGCAAAGGCTTGTTCGTTAAAGAACTTGAAGTTGCCATGCTTGAAGGCCGCGCCGATCTAGCCGTG
CACTCAATGAAAGACGTACCTGTCGACTTCCCTGAAGGCCTTGGCCTCGTGACCATTTGCGAGCGCGAAGACCCTCGCGA
CGCCTTCGTTTCTAATACCTATAGCAACATTAATGAACTCCCTCAAGGTGCGGTCGTCGGTACTTGCAGTTTGCGTCGCC
AATGCCAACTGAAAGAATACCGCCCAGACATCATTATCAAAGAACTGCGTGGCAACGTGGGTACTCGACTTGGCAAACTG
GATGCGGGTGAGTACGACGCGATCATTCTTGCAGCCGCAGGTCTAAAGCGCTTGAAATTGGAAGACCGAATTCGCAGCTT
TATCGAACCAGAACAATCACTGCCAGCGGTTGGCCAAGGCGCAGTCGGTATTGAATGCCGCGTAGACGACGAACGCTTAC
TCAAACTTCTGGAGCCACTCAACCATAAAGACACCGCCGATCGCGTGTTGTGCGAACGTGCCATGAACCTAACTCTTGAA
GGTGGCTGTCAGGTGCCAATCGGTAGCTACGCGCTACTTGAAGGTGATGAAATTTGGCTTCGCGCGCTAGTCGGTGAACC
AGATGGCAGCGAAATTGTGCGTGGCGAAGTGCGTGGTCACCGTAAAGATGGAGAAGCGCTCGGTATCCAGTTGGCTAACG
AGCTACTTGATAGCGGTGCCCGCGACATTCTAACCAAGCTGTACGCAGACCACGATTAA

Protein sequence : 
MTQSTPIRIATRKSPLALWQAHFVKDALQAAHPGLEVELVTMVTKGDVILDTPLAKVGGKGLFVKELEVAMLEGRADLAV
HSMKDVPVDFPEGLGLVTICEREDPRDAFVSNTYSNINELPQGAVVGTCSLRRQCQLKEYRPDIIIKELRGNVGTRLGKL
DAGEYDAIILAAAGLKRLKLEDRIRSFIEPEQSLPAVGQGAVGIECRVDDERLLKLLEPLNHKDTADRVLCERAMNLTLE
GGCQVPIGSYALLEGDEIWLRALVGEPDGSEIVRGEVRGHRKDGEALGIQLANELLDSGARDILTKLYADHD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-84 62
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-84 62