Gene Information

Name : alr (VP2734)
Accession : NP_799113.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 2899646 - 2900722 bp
Length : 1077 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAAAGCCGCAAAAGCATGCATTGACTTGTCTGCGTTGCAGCACAACTTGCAGCGTGTGAAAGCGCAAGCACCAGAAAG
TAAAGTGATGGCGGTAGTGAAAGCCAACGGTTATGGCCATGGTCTACGTCATGTGGCGAAACATGCTAACCATGCCGATG
CCTTTGGTGTGGCTCGCATTGAAGAAGCGTTGCAACTGCGCGCTTGTGGCGTGGTAAAGCCAATTCTCTTACTCGAAGGT
TTTTATTCGCCGGGCGATCTGCCTGTGTTAGTGACGAACAACATCCAAACCGTGGTGCACTGTGAAGAGCAACTTATCGC
GTTGGAACAGGCGGATTTAGAAACGCCAGTGGTCGTTTGGCTGAAGATCGACAGTGGTATGCATCGCTTAGGTGTTCGCC
CTGAGCAGTATGATGAATTCATTTCTCGCTTAAAAACGTGCCCGAATGTGGCGAAACCATTGCGATACATGAGCCATTTT
GGTTGTGCGGATGAGCTTGATAGCAGCATCACGCCGCAACAAATTGAGCTGTTTATGTCATTAACCTCGGGCTGTCAGGG
TGAGCGCTCGCTAGCGGCATCTGCGGGTTTATTAGCATGGCCTCAAAGCCAATTAGAGTGGGTTCGTCCGGGCATTATTA
TGTACGGCGTATCACCATTTAGCGACAAGACGGCCCAAGATTTGGGTTACCAACCAGTGATGACGTTGAAGTCTCATCTT
ATTGCGGTTCGTGAAGTCAAGCAAGGTGAAAGCGTGGGGTACGGTGGTATCTGGACAAGTGAACGCGACACAAAAGTCGG
CGTTATTGCAGTGGGCTATGGCGACGGCTACCCAAGAAGTGCACCCAATGGTACACCGGTGTGGGTGAATGGGCGTACAG
TACCGATTGCGGGTCGAGTATCAATGGATATGCTGACGGTAGACTTAGGTCCTGATGCCACAGATAAGGTCAGTGACGAA
GCGATTCTTTGGGGTAAAGAATTACCTGTCGAAGAGGTTGCGAATCACATTGGTACGATAGCTTATGAGTTGGTGACCAA
ATTGACGCCTCGCGTCGAAATGGAATATACCAAGTAA

Protein sequence :
MKAAKACIDLSALQHNLQRVKAQAPESKVMAVVKANGYGHGLRHVAKHANHADAFGVARIEEALQLRACGVVKPILLLEG
FYSPGDLPVLVTNNIQTVVHCEEQLIALEQADLETPVVVWLKIDSGMHRLGVRPEQYDEFISRLKTCPNVAKPLRYMSHF
GCADELDSSITPQQIELFMSLTSGCQGERSLAASAGLLAWPQSQLEWVRPGIIMYGVSPFSDKTAQDLGYQPVMTLKSHL
IAVREVKQGESVGYGGIWTSERDTKVGVIAVGYGDGYPRSAPNGTPVWVNGRTVPIAGRVSMDMLTVDLGPDATDKVSDE
AILWGKELPVEEVANHIGTIAYELVTKLTPRVEMEYTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 8e-57 41