Gene Information

Name : sirA; uvrY (VP1945)
Accession : NP_798324.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 2037468 - 2038112 bp
Length : 645 bp
Strand : -
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence : 
TTGATTAATGTTTTCCTTGTAGATGATCACGAGCTGGTTCGCACAGGGATACGACGTATTATTGAAGACGTCCGTGGAAT
GAACGTAGCAGGAGAAGCTGACAGCGGTGAAGATGCAGTTAAATGGTGTCGCAGTAATCATGCTGACGTCGTTTTAATGG
ACATGAACATGCCTGGGATTGGCGGCTTGGAAGCCACCAAGAAAATTCTTCGCGTGAATCCAGATGTGAAAATCATCGTA
CTAACCGTTCATACGGAAAATCCGTTTCCAACCAAAGTGATGCAGGCTGGTGCTTCTGGTTATTTAACCAAAGGTGCAGG
GCCGGATGAAATGGTAAATGCAATTCGTGTGGTCAATAGTGGGCAGCGTTACATCTCTCCAGAGATAGCGCAGCAAATGG
CATTGAGCCAGTTCTCACCAGCCTCTGAAAACCCATTTAAAGATTTGTCCGAACGTGAACTGCAAATCATGCTTATGATC
ACGAAAGGTCAGAAAGTAACGGATATTTCTGAGCAACTTAACTTAAGTCCAAAGACAGTCAACAGCTACCGCTATCGACT
GTTTAGCAAGCTGGACATTAATGGTGACGTCGAGTTAACACACTTAGCGATTCGCCACGGAATGCTGGACACCGAGACCC
TTTAG

Protein sequence : 
MINVFLVDDHELVRTGIRRIIEDVRGMNVAGEADSGEDAVKWCRSNHADVVLMDMNMPGIGGLEATKKILRVNPDVKIIV
LTVHTENPFPTKVMQAGASGYLTKGAGPDEMVNAIRVVNSGQRYISPEIAQQMALSQFSPASENPFKDLSERELQIMLMI
TKGQKVTDISEQLNLSPKTVNSYRYRLFSKLDINGDVELTHLAIRHGMLDTETL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 3e-51 50
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 3e-51 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sirA; uvrY NP_798324.1 response regulator VFG1889 Protein 4e-55 51