Gene Information

Name : VP1108 (VP1108)
Accession : NP_797487.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1167853 - 1169160 bp
Length : 1308 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGATTCTAAATTACTTCGTACAGAGCTGGATGAAACAGCTGCTAAACTGGCGCGTCGTGGCTTTAAGCTAGACGT
AGAGACTATTCGTAAACTTGAAGAACAACGTAAGTCCATTCAAGTAGAAGTAGAAAATTTACAATCCACGCGTAACTCCA
TTTCCAAGCAAATTGGCCAAAAAATGGCGGCTGGCGACAAAGAAGGCGCAGAAGAGATCAAGAAACAAATCGGTACTCTA
GGTAGCGATCTTGACGCGAAGAAAGTTGAACTTGAGCAAGTAATGGCTCAACTAGACGAATTCACGCTTTCTGTACCAAA
CATCCCAGCAGATGAAGTGCCAGATGGCAAAGACGAAAATGACAACGTTGAAATCTCTCGTTGGGGTGAGCCTAAGACTT
ACGACTTCGATTTGAAAGACCACGTTGACCTAGGCGAAATGGGTGGCGGTCTAGACTTCGCAAGTGCAGTTAAGATCACT
GGCGCACGTTTCATCGTGATGAAAGGTCAATTTGCTCGTCTACACCGTGCAATTGCTCAGTTCATGCTAGATCTTCATAC
AGAAGAACATGGCTACACAGAGATGTACGTACCTTACCTAGTGAACTCTGACAGCCTATTCGGTACTGGTCAGCTTCCTA
AGTTCGGTAAAGATCTTTTCCACACTGAGCCTCTAGCGGAAAAAGTAAACGACGAAGAGCCACGTAAACTGTCTCTAATC
CCTACAGCAGAAGTACCAGTAACGAACCTAGTTCGTGACACTATCACTGACGAAGCGGATCTACCTATCAAGATGACAGC
CCACACGCCATGTTTCCGTTCAGAAGCGGGTTCATACGGTCGTGATACTCGTGGTCTGATTCGTATGCACCAGTTCGACA
AAGTTGAGCTAGTACAAATCACGAAGCCAGAAGATTCAATGACCGCGCTAGAAGAGCTAACAGGTCACGCTGAGAAAGTT
CTACAACTTCTTGAACTTCCTTACCGTAAAGTCGTTCTATGTACAGGCGACATGGGCTTCGGCGCTCGTAAAACTTACGA
CCTAGAAGTTTGGGTTCCTGCTCAAGAGACTTACCGTGAAATCTCTTCATGTTCTAACATGTGGGACTTCCAAGCTCGTC
GTATGCAAGCGCGTTTCCGTCGTAAAGGCGAGAAGAAACCTGAGCTTGTGCACACGCTAAACGGTTCTGGTCTAGCAGTT
GGTCGTACCATGGTTGCTATCCTAGAAAACAACCAAGAAGCAGACGGTCGCATTGCAATCCCTGCAGTACTTCAGAAGTA
CATGGGCGGCGCAACGCACATCGGTTAA

Protein sequence :
MLDSKLLRTELDETAAKLARRGFKLDVETIRKLEEQRKSIQVEVENLQSTRNSISKQIGQKMAAGDKEGAEEIKKQIGTL
GSDLDAKKVELEQVMAQLDEFTLSVPNIPADEVPDGKDENDNVEISRWGEPKTYDFDLKDHVDLGEMGGGLDFASAVKIT
GARFIVMKGQFARLHRAIAQFMLDLHTEEHGYTEMYVPYLVNSDSLFGTGQLPKFGKDLFHTEPLAEKVNDEEPRKLSLI
PTAEVPVTNLVRDTITDEADLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQITKPEDSMTALEELTGHAEKV
LQLLELPYRKVVLCTGDMGFGARKTYDLEVWVPAQETYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGSGLAV
GRTMVAILENNQEADGRIAIPAVLQKYMGGATHIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-97 56