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Name : irp5 (PSPTO_2597) Accession : NP_792406.1 Strain : Pseudomonas syringae DC3000 Genome accession: NC_004578 Putative virulence/resistance : Virulence Product : yersiniabactin synthetase, salycilate ligase component Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : - Position : 2870283 - 2871851 bp Length : 1569 bp Strand : - Note : Activates salicylate by adenylation and transfers the salicylyl moiety to irp2, the non-ribosomal peptide synthetase component of yersiniabactin synthetase. Yersiniabactin is a siderophore.; see PMID:20190049 for expression data; similar to SP:P40871, GP: DNA sequence : ATGCACACCGAACACACGTCTCACGACCCGCTGCACCCCTTCGCCGACCAGACCCTCCCTCAACGCCTGCGTCGCTGGGC GAACCAGTACGGCGCGCACACCGCGCTGGTCGCAGGCGACGTACGCCTGAGCTACGCGCAGCTGGACCAGCGGGTTGATC GCCTGGCCGGGGGCCTTGCAGCGCTGGGCATTACGGCAGGTGACCGGGTCATGCTGCAACTGCCCAACGGTGTCGGCTTT GTCTGCGCATTGTTTGCCGTGATGCGCATCGGCGCGGTACCGGTATTGGCCATGCCCACCCAGCGTGCAGTGGACATTGC AGCGCTGTGCCGGTTGGCCGAACCTGTGGCCTACCTGATCCCCGATCGCCTTCGGGACTTCGATTACCGGGGCATGGCAG CCGGCATCGTCGAGCAGCAGCCCTCACTGGCGCACGTCATTGTCGATGGCGAACCCGGGCCTTTCATCGCCTTGTCGGCG CTGGATGCCCCCTGCCCGACCGATCCGCTGGCCGACCCGCGCGGGCTGGCCTTGCTGCTGCTTTCAGGCGGCACCACCGG CACGCCAAAACTGATCCCGCGCAGCCACGCCGACTACGCCTACAACTTTTCCCACTCGGCCAGGCTCTGTGAACTGGACA GCGATAGCGTGTACCTGGCCGTGTTGCCGACCGCGCACAATTTCACCCTTGCCTGCCCCGGCGTGCTCGGCAGTCTGGCC GCCGGTGCGACGGTGGTAATGGGCGACAGCGCCAGTTGTGATGCGGCCATGCCGTTGATCGAGCGCGAAGGCGTCACCCA TGTGGCGCTGGTCCCGCCGCTGGCGCAACTCTGGGCCCAAGGGCGCGACTGGGAGGACAGCGACCTGACCAGCCTGAAGC TGCTGCAAGTCGGCGGCTCGCGACTGGACCCGGCACTGGCAGCCCACCTGCTTGAAGCGCTGGACTGCCAAATACAACAG GTGTTCGGCATGGCCGAGGGCCTGCTGTGCTACACCCGCCCGGACGATCCGCTGGAAGTGGTGCTCAATACGCAGGGCCG TCCATTGTCGCCGTTCGACCAGGTTCGTCTGGTGGACACCGACCTGAATGACGTTGCTCATGGCCAGACCGGCGAACTGC TGACCCGCGGCCCCTACACCATTACCGGGTATTACCGGGCGGCAGATCACACTGCGCGCAGTTTCACCGCCGATGGCTAC TACCGCAGCGGCGACCTTGCGCGCTGGACGCCGCAAGGCAACCTGATCGTCGAAGGGCGCATCAAGGAACAGATTCAGCG CAGCGGTGAAAAGATCTCTGCGGCACACATCGAAAATCACCTCACGGCGCTGCCCGACATCGAATCTGCCGTCGTGGTGG CGGTGCCGGATCCGCTGCTGGGCGAACGCATCTGCGCGTTCATTCTGGGCGACCCGCCAACGGGTGCCGGCCAATGCATT CGCGACCAACTGCGTCGGCAGGGGCTGGGTGAAGACAAGCTGCCCGATCAGTTCGAGTGGGTTGCCGCATGGCCGCTGAC GGCCGTGGGCAAGATCGACAAACGCCAACTGGCCGCTCTGGCCCAGTGA Protein sequence : MHTEHTSHDPLHPFADQTLPQRLRRWANQYGAHTALVAGDVRLSYAQLDQRVDRLAGGLAALGITAGDRVMLQLPNGVGF VCALFAVMRIGAVPVLAMPTQRAVDIAALCRLAEPVAYLIPDRLRDFDYRGMAAGIVEQQPSLAHVIVDGEPGPFIALSA LDAPCPTDPLADPRGLALLLLSGGTTGTPKLIPRSHADYAYNFSHSARLCELDSDSVYLAVLPTAHNFTLACPGVLGSLA AGATVVMGDSASCDAAMPLIEREGVTHVALVPPLAQLWAQGRDWEDSDLTSLKLLQVGGSRLDPALAAHLLEALDCQIQQ VFGMAEGLLCYTRPDDPLEVVLNTQGRPLSPFDQVRLVDTDLNDVAHGQTGELLTRGPYTITGYYRAADHTARSFTADGY YRSGDLARWTPQGNLIVEGRIKEQIQRSGEKISAAHIENHLTALPDIESAVVVAVPDPLLGERICAFILGDPPTGAGQCI RDQLRRQGLGEDKLPDQFEWVAAWPLTAVGKIDKRQLAALAQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 5e-134 | 58 |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 7e-134 | 58 |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 3e-132 | 58 |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 2e-132 | 58 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 2e-132 | 58 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 2e-132 | 58 |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 2e-132 | 58 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 2e-132 | 58 |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 2e-132 | 58 |
| irp2E | YP_005163485.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 6e-77 | 41 |
| irp2E | YP_005134497.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 5e-77 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| irp5 | NP_792406.1 | yersiniabactin synthetase, salycilate ligase component | VFG1817 | Protein | 9e-103 | 50 |
| irp5 | NP_792406.1 | yersiniabactin synthetase, salycilate ligase component | VFG0168 | Protein | 2e-104 | 49 |
| irp5 | NP_792406.1 | yersiniabactin synthetase, salycilate ligase component | VFG0932 | Protein | 2e-78 | 43 |
