Gene Information

Name : TWT623 (TWT623)
Accession : NP_787751.1
Strain : Tropheryma whipplei Twist
Genome accession: NC_004572
Putative virulence/resistance : Unknown
Product : nicotinate phosphoribosyltransferase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1488
EC number : 2.4.2.11
Position : 729436 - 730764 bp
Length : 1329 bp
Strand : +
Note : catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate

DNA sequence :
GTGGGCGGTGCAGGTCTCCTAACAGACCAATACGAGTTGTCGATGGTCAACGCAGCACGAATATCAGGGATAGCTGCTAA
AGAATGTGTTTTTGAGGTTTATTCTCGCGCATTGCCACCTGGCAGGCCATTTGGTGTGTTTGCAGGCCTTGAGAGGCTGC
TGGAAAAAATCGAAAATTTCTCCTTTGCAGATGACGAAATTACATGGCTTAGAGAAAAGAATATCGTTGATAATGAGACA
CTTGACTGGCTCCGGGGGTATAGCTTTTCTGGGTCAATTTCTGGCCACAAAGAGGGGGAAATCTTTTTCCCCAATACACC
CGTTCTAACTGTTAGAGCACCATTTGCAGAAGCAGTAGTTCTCGAAACCCTGATCCTAAGTTGCATAAATTTTGATAGCG
CTATTGCGTCAGCGGCGGCACAACTTGTGTATCGCGCAAAAAACAAACCAGTTTATGAAATGGGCTCCAGAAGAACAAAT
GAACAGGCCGCTGTAGCAGCGGCGCGGGCTGCGTACATTGCTGGGTTTGCCGCAACAAGCAATCTGGCAGCTGGGAAGAT
TTGGGATATACCAACCGTTGGAACTATGGGTCATGCATTTATACTTGCTCATAAAACGGAGAGTGAAGCTTTTTATGCAC
AGCTCAAACAGGGTGGGGGAAACAATATAACCCTCTTGATTGATACATACGATATCCAGGAAGCAATTGACAGTGCGGTA
ACTGTCGCAGGCAAAAATCTTGCAGCTGTAAGAATAGATTCGGGAAACCTACCAGAAGTGGTGCACGATGTACGCAGAAA
GCTCGACCTCGCGGGTGCAACTGAGACAAAGATCATTCTCACAGGCGACCTTGATGAGGCCTCAATTAGGCTCGTAAGCA
CCGCACCGGTTGATGCACTCGGGGTTGGAACATCTCTGGTAACTGCGGGAGGATTTCCATCTGCAGGCTTCGTTCATAAA
CCGGTGGCATGCAGAGAAAAAAACAGATGGAGAATGCTTTCGAAAAAATCAAAAAACAAAGTTAGCACCGGCGGGCAAAA
AAATGTCCAAAGAGTTCTTGACAAAAACAAGAAGATTATCAAAGAGCAAGTCCTCGTATTTGATCCCGATAATCCCCCAG
TGACAACCTATGACACGAATGTATTACAGATTACGAGTGAACATATAAGGCACGGAAAAAGAGTTGCAATAAACTCAACA
AATGAAATAAGGGCGTATCACAAATCGGTTATCAATCAAATCCCAGAAGAAGTATTCAACCTTGAGGGCAAAATAAATAC
CGAGCGGATCTCCTGGCATAGTGTGCAAGGCCATCGTCTAGAGGCCTAG

Protein sequence :
MGGAGLLTDQYELSMVNAARISGIAAKECVFEVYSRALPPGRPFGVFAGLERLLEKIENFSFADDEITWLREKNIVDNET
LDWLRGYSFSGSISGHKEGEIFFPNTPVLTVRAPFAEAVVLETLILSCINFDSAIASAAAQLVYRAKNKPVYEMGSRRTN
EQAAVAAARAAYIAGFAATSNLAAGKIWDIPTVGTMGHAFILAHKTESEAFYAQLKQGGGNNITLLIDTYDIQEAIDSAV
TVAGKNLAAVRIDSGNLPEVVHDVRRKLDLAGATETKIILTGDLDEASIRLVSTAPVDALGVGTSLVTAGGFPSAGFVHK
PVACREKNRWRMLSKKSKNKVSTGGQKNVQRVLDKNKKIIKEQVLVFDPDNPPVTTYDTNVLQITSEHIRHGKRVAINST
NEIRAYHKSVINQIPEEVFNLEGKINTERISWHSVQGHRLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1473 YP_001800867.1 nicotinate phosphoribosyltransferase Not tested Not named Protein 1e-61 45