Gene Information

Name : nadE (TWT405)
Accession : NP_787533.1
Strain : Tropheryma whipplei Twist
Genome accession: NC_004572
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 494945 - 495820 bp
Length : 876 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
TTGTGGTCCAGGATGTCGCGGGTTCGAGTCCCGTTATCCACCCTGAGTTCTGGGAGTTTTGTGTGTTGTGATATATCAAA
GACTCTATGCGTGAAGCCGTTTATAGATCCTGAAGAAGAGATCTCACACAGGGTGTCGTTTCTGGCCGATTATTTGCGCC
ATTCCCGCGCATCGGGTTATGTTCTTGGTATAAGCGGTGGACAGGATTCCGCCCTGGCCGGTAGATTGTGCCAGATCGCC
GTTGAAAGTGTGCGATCTATTGGTTTTGATGCAACCCTCTGGGCCATCCGCCTACCCTACGGGCAACAGTTTGATGAGTC
TGATGCCCAAACTGCAATGCAATTTATATCTCCCGATGAGGAGCTTAGTTTCGACATACGTAGCGCAACAGACAATCTAT
GCGTGGATCTCAATAGGTCTCTTGGGTCTAAGATAAGCGATTTTAATCGCGGCAATATAAAAGCAAGGTTGCGCATGGTT
GTGCAGTACGCGGTTGCCGCCCATCATGATGCTCTTGTTGTTGGAACAGATCATGCGGCTGAGGCAGTAACCGGGTTTTT
TACAAAATTTGGTGATGGCGCAGCAGATATTTTGCCTCTATACGGTCTTACAAAGGGTCAAGGCAGGGCTCTCCTCAAAG
CCCTTGGCGCATGCGACTCAATTATCGAAAAAGTTCCAACAGCCGATTTATTAGACGATTTACCGTGTTTGCCTGATGAA
ACTGAGTTAGGGTTACAGTACCGAGATATAGATGCCTTTTTGGAAGGAAAACCGGTTTCTGAAGATATTACGATGGCTAT
TACTGAGCGGTACAAATCGACCCTTCATAAAAGAATGCCCCCCATAACCCCACACTCAACATGGTGGCGCAAATAA

Protein sequence :
MWSRMSRVRVPLSTLSSGSFVCCDISKTLCVKPFIDPEEEISHRVSFLADYLRHSRASGYVLGISGGQDSALAGRLCQIA
VESVRSIGFDATLWAIRLPYGQQFDESDAQTAMQFISPDEELSFDIRSATDNLCVDLNRSLGSKISDFNRGNIKARLRMV
VQYAVAAHHDALVVGTDHAAEAVTGFFTKFGDGAADILPLYGLTKGQGRALLKALGACDSIIEKVPTADLLDDLPCLPDE
TELGLQYRDIDAFLEGKPVSEDITMAITERYKSTLHKRMPPITPHSTWWRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 3e-58 54