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Name : tkt (TWT340) Accession : NP_787468.1 Strain : Tropheryma whipplei Twist Genome accession: NC_004572 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 421805 - 423901 bp Length : 2097 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGGAATATAATGTTTCGCGGGAACGGAGGGTTTCTGCTTTGACTGTGTTTGTTTGGGATGATAAGGATGATCTGGCGGT AAACACAGCCCGGGTACTTGCGGCAGACGCAGTTGAAAATGTCGGGAACGGTCACCCCGGAACGGCGATTAGTTTGGCAC CCGCTGCTTATCTTTTGTTTCAGAAGGTTATGCGCCATAACCCCTCTGATCCTTCCTGGGCGGCGCGCGATAGATTCGTG TTATCCTGCGGTCATAGTTCACTTACCCTATATATTCAGCTTTTTCTGGCCGGCTATAAACTTTCCCTGCAGGATCTTCG AGGCCTTCGCCAGTGGGGCTCGCTGACTCCCGGACACCCGGAATATGGGCATACACCCGGGGTTGAAATTACAACAGGTC CTCTTGGTCAAGGCCTTGCTAGCGCTGTTGGGTTTGCATATTCCGCGCGGTTCCAAAGGGGCCTCTTCAAGACGGATATA TTCGATCATTATGTCTATGTGATCGCGAGTGAAGGTGATATAGAAGAAGGTGTTACTTCTGAGGCATGTTCTCTTGCTGG ACTTCAGCAGCTCGGTAATCTTTTGGTGATTCTTGACAGAAACTATATAAGTATCGAAGATAATACTGATATAGCCCTTT CTGAAGATATAAAGTCCAGATATCTGTCATACGGTTGGCAAGTAATCGAGGTTCCCTGGCGTCGAGCAGGGGCAGAGTAT AGGGAGGATGTCCTCTCCCTCTATGAGGCCCTCTTGGAAGCGCAAAAGGATACTGATAGACCGTCGCTAATAATCCTGGA AACGGTTATCGCTTGGCCATCACCGGGCAAACAAAATACGGGCGCTGCGCATGGTGCTGCACTTGGCGTAAATGAAGTGA AAGACCTGAAGCGTATTCTGGGTTTTGATCCCGAAAAAACATTCGAGGTTCCAGACGGTGTTCTTCAGCACACTAAAGGG GCACTTGATCGAGGCCAGTCACAGCAGGACAATTGGGAAAATGTCTTTTCATCTTGGCGTCAAGAGCATCCCATTGAGGC TGCTTTATTTGACAGATTACAAAATGGGGTTACTCCGGATATAGATCATGTTTTGCCTGTTTTTTCCTCGGAGAAACCGA TTTCTACCAGGGCGGCCAGTGGGCAAGTTATAAACCGTATCGCTGAAGTTATGCCAGAGTTATGGGGCGGGTCGGCGGAT CTCGCAGAATCGAATAATACGACTATAAAGTCTGCGAACAGTTTCTTACCCGAAAGTGTGACAGTTGATCATTGGAAATC TGATCGTTATGGTCGCATCCTGCACTTTGGAGTGAGGGAACATGCGATGGCTGCGCTAATAAGCGGAATTGTTCTCCACG GGAATACAAGGGTATTTGGTGGGACTTTTTTGGTTTTCAGTGACTATATGCGTCCTGCGGTTAGACTTGCTGCACTCATG AAGATACCATCTATTTTTGTTTGGACTCATGACTCAATAGGACTGGGAGAAGATGGGCCGACTCATCAACCGGTTGAACA TCTTTGGGCCTTGCGTGCCATCCCTGGTTTATCTGTCATTCGGCCCGCTGATGCTAACGAGGTTGCCTGGGCTTGGAAAG AAATTCTTGAGAGGCGTGATGGTCCGGTTGGGCTTGTTTTATCACGACAAAATCTTCCTGTGCTCGACAGGACTTGTCTT GCACCTGCCAGCGAACTCAGAAAGGGAGCGTATATCCTAGCTGATGGATCGCGTTATCCGAGATTGATATTAATCGCGAC GGGCTCAGAGGTCTCGCTGGCAATAGGTGCTAGGGAAGTTCTTGAAAATCGTGGTATTCCCACAAGAGTGGTTTCGGCGC CGTGTCTTGAGTGGTTCGATCAACAAGAGAAAAGTTACCGCAACCATGTCCTTCCTCCAGACGTAGAAACCAGAATTTCT GTTGAGGCAGGTTTGTCGCTGGGTTGGTCGAAGTATATTGGAGATAAGGGCGCATCCGTTTCTATAGAACACTATGGAGC ATCAGCCGCTGGGGATGTTCTTTTTGAACGTTTCGGTTTTACCGTTGAGAATATTGTAAAAACAGCAGATGCTCTGTTGG GAGGGTGTGGTGAATAG Protein sequence : MEYNVSRERRVSALTVFVWDDKDDLAVNTARVLAADAVENVGNGHPGTAISLAPAAYLLFQKVMRHNPSDPSWAARDRFV LSCGHSSLTLYIQLFLAGYKLSLQDLRGLRQWGSLTPGHPEYGHTPGVEITTGPLGQGLASAVGFAYSARFQRGLFKTDI FDHYVYVIASEGDIEEGVTSEACSLAGLQQLGNLLVILDRNYISIEDNTDIALSEDIKSRYLSYGWQVIEVPWRRAGAEY REDVLSLYEALLEAQKDTDRPSLIILETVIAWPSPGKQNTGAAHGAALGVNEVKDLKRILGFDPEKTFEVPDGVLQHTKG ALDRGQSQQDNWENVFSSWRQEHPIEAALFDRLQNGVTPDIDHVLPVFSSEKPISTRAASGQVINRIAEVMPELWGGSAD LAESNNTTIKSANSFLPESVTVDHWKSDRYGRILHFGVREHAMAALISGIVLHGNTRVFGGTFLVFSDYMRPAVRLAALM KIPSIFVWTHDSIGLGEDGPTHQPVEHLWALRAIPGLSVIRPADANEVAWAWKEILERRDGPVGLVLSRQNLPVLDRTCL APASELRKGAYILADGSRYPRLILIATGSEVSLAIGAREVLENRGIPTRVVSAPCLEWFDQQEKSYRNHVLPPDVETRIS VEAGLSLGWSKYIGDKGASVSIEHYGASAAGDVLFERFGFTVENIVKTADALLGGCGE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 2e-114 | 44 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 3e-113 | 41 |
