Gene Information

Name : thiC (CTC00828)
Accession : NP_781489.2
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 877273 - 878589 bp
Length : 1317 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATTATACAACTCAAATGGATGCTGCTAAAAGAGGAATAGTTACCAAGGAAATGGAAACTATAGCTAAAAAAGAAGG
CATAGATGTAAAAAAAATAATAGAATGTGTAGCAAAAGGTAGTGTTGCTATACCTGCAAATAAAAATCATAAAAGTTTAA
GTGCCGAAGGAGTAGGACAAGGGCTAAGAACTAAAATAAATGTAAATCTAGGTATATCAAAAGATTGTTGTAATGTAGAT
AGAGAACTTGAAAAAGTAAAAAAAGCTATAGATATGAAGGCTGAAGCCATAATGGATTTAAGTTGTTTTGGAAAGACACA
AGAATTTAGGAAAAGATTAATAGAAATGTCACCAGCCATGATAGGAACTGTTCCAATGTATGATGCTATTGGATTTTATG
ATAAAGAGTTAAAAGATATTACCGCAGAAGAATTGCTAGATGTAATAGAAACTCATGCAAAAGATGGAGTAGACTTTATG
ACTATCCACGCAGGACTTAACAGAGAAGCTGTGGAAATATTTAAGAGAAATGAAAGACTTACTAACATAGTATCCAGAGG
AGGGTCTCTTCTTTATGCATGGATGGAACTTAATAATAAGGAAAATCCTTTCTATGAACATTTTGATAAAGTACTCGATA
TATGTGAAAAATATGATGTTACAATAAGCTTAGGAGATGCTTGTAGACCAGGTTCAATACATGATTCTACAGATGCAAGC
CAAATAAAAGAACTTATGACTTTAGGGGAATTAACTAAAAGGGCATGGGAAAGAAATGTTCAAATTATAATAGAAGGACC
TGGACACATGTCCTTAGATGAAATAGAAACAAATATGAAATTAGAAAAAAAATTATGTTATAATGCACCTTTTTATGTAT
TGGGGCCTATAGTTACAGATATAGCTCCTGGATATGATCATATTACAAGTGCTATAGGAGGAGCAATTGCTGCAACTTAT
GGAGCAGACTTTTTATGCTATGTAACTCCAGCAGAACACTTAAGACTTCCTGATTTAGATGATATGAAAGAAGGTATAAT
AGCAACTAAAATAGCAGCTCATGCAGCAGATATTGCTAAAGGAATAAAAGGGGCAAGAGAATGGGATAATAAAATGTCCG
TTGCAAGAAAAGAGTTAGATTGGGAAAAGATGTTTGATTTGGCTATAGATAATGAGAAGGCAAGAAAGTATAGAAAGAAT
TCAACACCAGAGGTTAACGATAGTTGTACAATGTGTGGAAAAATGTGTGCTGTTAGAAATATGAATAAGGTTATGCAAGG
AAAAGATATAAATATATTGAGAAACGAGGATAAATAA

Protein sequence :
MNYTTQMDAAKRGIVTKEMETIAKKEGIDVKKIIECVAKGSVAIPANKNHKSLSAEGVGQGLRTKINVNLGISKDCCNVD
RELEKVKKAIDMKAEAIMDLSCFGKTQEFRKRLIEMSPAMIGTVPMYDAIGFYDKELKDITAEELLDVIETHAKDGVDFM
TIHAGLNREAVEIFKRNERLTNIVSRGGSLLYAWMELNNKENPFYEHFDKVLDICEKYDVTISLGDACRPGSIHDSTDAS
QIKELMTLGELTKRAWERNVQIIIEGPGHMSLDEIETNMKLEKKLCYNAPFYVLGPIVTDIAPGYDHITSAIGGAIAATY
GADFLCYVTPAEHLRLPDLDDMKEGIIATKIAAHAADIAKGIKGAREWDNKMSVARKELDWEKMFDLAIDNEKARKYRKN
STPEVNDSCTMCGKMCAVRNMNKVMQGKDINILRNEDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-59 45
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-59 45