Gene Information

Name : CTC00114 (CTC00114)
Accession : NP_780829.1
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 72416 - 73750 bp
Length : 1335 bp
Strand : +
Note : unwinds double stranded DNA

DNA sequence :
ATGGACGCACCATTAAGAAGTATGCCTCAAAATATTGATGCAGAACAATCTGTACTAGGAGCTATGATAATAGATAAGAC
TTCCATAGCACAAGCTTTAGAAGTCTTAAATAAAGAAGATTTTTACAAAGAAGCTCATCAAACAATATATGAGGCAATTT
TAGATTTATATAAAAAAGATGTTGCAGTGGATATGGTTACTATAACTGAAAATCTTCAATCAAAAGAAAAACTAGAATTA
GTTGGTGGAGTAACTTATATAAGTGAAGTTGGTACTTCCGTTATATCTACTGCTAATTTGCAATCCTATATTGATATAGT
TAAAGATAAATCTACATTAAGAAAGCTTATAAGAGCATCAACAGAAATAATTAACGATAGTTATAATAAGCAAGATGATG
TAGTTAATGTGGTAGATTCAGCAGAAAAGAAAATATTCAATATAGGTATTAACAGAAATGCTAGTGATTTTGAGGCTATG
AATACAGTACTAGAAAGAGGATTTTTAGAAATTGAGAAAATATTTAACAATAAAGGTGGAGTAACAGGTGTACCATCAGG
ATTTCCAGAACTAGATAGCAAAACATCAGGTTTTCAAAAGGGAGACATGATTCTAATAGCAGCAAGACCTTCTATGGGAA
AAACAACTTTCGCATTGAACTTAGCACAATATGCAGCGTTGAGAGAAGGAAAGAGTATAGCAGTATTCTCTTTAGAGATG
TCTAAAGAACAGCTGGCCTATAAACTTTTATGTTCAGAAGCCAATGTTGATATGTTAAAGTTAAGAACAGGTAATTTAGA
AGATAAAGATTGGGAAAATATAGCTAAAGCATCAGGACCATTATCTTTAGCAAAAATATACATAGACGATACACCAGGTA
TAACTGTAATGGAAATGCGATCAAAATGTAGAAGGCTAAAAATGGAAAGAGGAATAGACATGATAGTAATAGACTATCTT
CAACTTATGGCTGGAAGTAGATCAAGTGAAAGTAGACAGCAGGAAGTATCTGAAATATCCAGATCTATTAAAGCTTTAGC
AAAGGAAATGGAATGTCCTGTTATCGCTCTATCACAGTTATCCCGTGCACCAGAACAAAGAACAGATCATAGACCTATGT
TATCTGACTTAAGAGAGTCAGGATCCATTGAGCAAGATGCAGATTTAGTAATGTTTTTATATAGGGATGAATACTACAAT
AAAGAAACTGAAGAAAAAAACGTAGCTGAATGTATAATATCTAAACAAAGAAATGGTCCTACAGGAACAGTTAAATTAGC
CTGGTTAGGACAATATAGCAAATTTGCAAGATTGGATATTATACACCAAGAATAA

Protein sequence :
MDAPLRSMPQNIDAEQSVLGAMIIDKTSIAQALEVLNKEDFYKEAHQTIYEAILDLYKKDVAVDMVTITENLQSKEKLEL
VGGVTYISEVGTSVISTANLQSYIDIVKDKSTLRKLIRASTEIINDSYNKQDDVVNVVDSAEKKIFNIGINRNASDFEAM
NTVLERGFLEIEKIFNNKGGVTGVPSGFPELDSKTSGFQKGDMILIAARPSMGKTTFALNLAQYAALREGKSIAVFSLEM
SKEQLAYKLLCSEANVDMLKLRTGNLEDKDWENIAKASGPLSLAKIYIDDTPGITVMEMRSKCRRLKMERGIDMIVIDYL
QLMAGSRSSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRTDHRPMLSDLRESGSIEQDADLVMFLYRDEYYN
KETEEKNVAECIISKQRNGPTGTVKLAWLGQYSKFARLDIIHQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 4e-75 43
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 2e-71 41
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 4e-71 41