Gene Information

Name : hemC (CTC00727)
Accession : NP_781392.2
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 752878 - 753750 bp
Length : 873 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAAGTTAATAGTAGCCACAAGAAGGAGTATTTTAGCACAAACTCAAACAGATTTAGTAATAAAGAAAATAGAGGAAGA
TAATGAGGTAAAATGTGAAAAACTTTTAATTCAAACTCTAGGGGATAAAATATTAGATAGAACCCTAGATAAAATAGGAG
GGAAGGGACTATTTATAAAAGAAATAGAGAAGGCCTTATTAGATGGAAAAGCTCATATGGCAGTACATAGCATGAAGGAT
GTTCCCTATGAAGTACCTTCTATGTTTTATATAGGAGCAATTCCTAGAAGAGAAGATGTAAGAGATGCATTTGTATCAAG
AGATGGTACAAAATTTATGGAGCTACCATCAGGTTCTAAAATAGGAACAAGTAGCAGAAGAAGATCAAGTCAGATTAAAA
TTCTAAGACCTGACGTGGAAGTTGTACCTATAAGGGGTAATGTTCAGACTAGATTAAGAAAAATAGAGGAAATGAATTTA
GCAGGCACTATTTTAGCGGTAGCTGGACTAAAGAGACTAAATATGGAAGAAGTTATTACAGATTATTTTAGTCCAGAGGA
AATGGTACCAGCTATAGGACAAGGAGCTTTAGGAATAGAAATAAAAAAATACGAGGATGTTATTGATTATATAAAAGGTA
TAGATCATGAAGAAACTAGAATATGTGTAGAGGGCGAAAGAAGTTTTATGGAAGCTTTAAAGGGAGACTGTCATTCAACT
ATAGGAGCTCATGCTATAGTTGAGAATGATTTAATGTATATGACAGGAATATTTGAAGTTAATGGAAAAATTGTAAAGAA
AGATATTGAAGGTAAGAAAGAAAATTATAAACAACTAGGAAAAACATTAGCAGATAGAATAATGAAGGCTTAA

Protein sequence :
MKLIVATRRSILAQTQTDLVIKKIEEDNEVKCEKLLIQTLGDKILDRTLDKIGGKGLFIKEIEKALLDGKAHMAVHSMKD
VPYEVPSMFYIGAIPRREDVRDAFVSRDGTKFMELPSGSKIGTSSRRRSSQIKILRPDVEVVPIRGNVQTRLRKIEEMNL
AGTILAVAGLKRLNMEEVITDYFSPEEMVPAIGQGALGIEIKKYEDVIDYIKGIDHEETRICVEGERSFMEALKGDCHST
IGAHAIVENDLMYMTGIFEVNGKIVKKDIEGKKENYKQLGKTLADRIMKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-48 43
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-48 43