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Name : leuS (CTC00337) Accession : NP_781040.1 Strain : Clostridium tetani E88 Genome accession: NC_004557 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 323610 - 326096 bp Length : 2487 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAAGGTTTTTTATTTTATAAAAATTTATAAAAAGGAGAGATACTTAATGGGAAACTACGGAACTAATATAGATAGAAA ATGGCAAAATAAATGGGAAGATTCTAATCTTTATCATTTCGATACAAATAACTTAGATAAAAAACTTTATGTTTTAGAAA TGTTTTCTTATCCATCTGGAAGTAATCTTCATGCAGGACACTGGTTTAACTATGGTCCTTCAGATTCTTGGGCTAGGTTT AAAAGAATGCAGGGATTTAATGTATTCCAACCTATGGGATTTGACTCTTTTGGATTACCTGCAGAAAATTATGCTATAAA AACTGGTGTTCATCCAAAAGATTCCACTATGAAGAATATAGAAACTATGACAAAACAACTTAAGTCTATGGGTGCCATGT TCCATTGGGATAATGAAGTAATAACTTCTGAACCAGAATATTATAAATGGACTCAATGGATGTTCCTTCAGCTTTATAAA AATAATTTAGCTTATAGAAAAAATGCACCTGTAAACTGGTGCCCAAGTTGTAATACAGTACTTGCTAATGAACAGGTTTT AGATGGAGCTTGTGAAAGATGTTCCTCTGACGTTATTAAAAAAGACTTAACTCAATGGTTTTTTAAGATAACAGATTACG CTGAAGAACTTCTTGAAAAACTTGATGATTTAGATTGGCCTGAGAATACAAAATCCATGCAAAAACATTGGATTGGAAAA TCTATAGGTGCTCAATTAACTTTTAAAATAGTTGACTCTGATCTTTCTTTTGATATATTTACAACAAGAGCAGATACATT ATTTGGTGTAACCTATGCAGTTTTAGCACCTGAAAATCCTCTTGTAGATAAAATAACTAAGGAAGACCATAAAGCTGAAA TTGAAGCTTATAAAGAACAAGCTAAAAAACAATCTGAAATAGAAAGACAATCAATAACAAGAGAAAAGACTGGAGTATTT ACAGGTTCTTATGCTATAAATCCTATTAACGGAAAAAAGGTTCCTGTTTGGGTTGGTGACTATGTATTAAGCACTTATGG TACTGGTGCAGTTATGGCTGTTCCAGCTCACGATGAAAGAGATTTTGAATTTGCAAAAAAACATAACCTACCTATAGAAA AAGTTATAGAAGGAGGAGAAACTCTTCCTTACACTGAAGATGGAATAATGATAAATAGTGAAGAATTTAATGGTTTGGAA TCCTCAAAGGGTAGATCTGCTGTTGTAGAAAAACTAGAAAAAGAAAACCTTGGAGTTAAAAAAATTAATTATAGATTAAG AGATTGGTTGGTCTCTAGACAAAGATACTGGGGTGCTCCAATTCCAATAGTATATTGTGATAAATGTGGTACTGTTGCTG TACCTGAAGAACAACTACCTGTTAAGCTTCCGTATGATGTAGAATTTACACCAGATGGAAAATCTCCACTTTCTAAATGT GATAGCTTTGTAAATACAACATGCCCTACTTGTGGAGGACCTGCTAAAAGGGAAGTAGATACATTAGATACTTTTGTATG TTCATCTTGGTATTTCTTAAGATATGCAGATAATAAAAATTCTGAAAAAGCCTTTGACCCTAAAATAATAAATGAAATTC TTCCAGTAGATAAATATGTAGGAGGACCAGAACATGCTTGTATGCATCTTTTATATGCAAGATTTTTTACAAAAGCATTA AGAGATATGGGATACCTTAATTTTGATGAACCATTCTCATCTTTAACACATCAAGGACTAATATTAGGACCTGATGGATT AAAGATGAGTAAATCTAAAGGAAATACCATTTCTCCAGATGATTATATAGATGAATTTGGCTCCGATGTTTTTAGAATGT ATTTAATGTTTGGATTTGATTACACTGAAGGTGGAGCTTGGAGCGATGAAGGAATCAAATCTGTTTCTAGATTCGTAGAC AGAGTAGAGAGAACTCTTGCCTCTTGTAGATACTATATTAATAATCCTAGTGATGATAAAATCACTATAGATAACAATGA AAAGGACTTAAATTTTGTTAGACATAATTCTATAAAATCTATAACAGAAGATGCTGAAAAAATGCAATTTAACACATGCA TTGCAAGACTTATGGAATATACAAATGCTCTTTCAAAATATATAAATGAAGATAACAAAAACTCAAAGTTCTTAAAAGAA TGTGTAGAGGATTTTATAATTTTAATAGCTCCTTTTGCACCTCATTTTAGTGAAGAACAATGGGAACTTCTAGGAATGAC TTACTCTGTATTCAATGAAAAGTGGCCACAATTTGACAGTAAAGCTTTAGTCAAGGACGAAATTGAAATTGCTGTTCAAG TAAATGGTAAAATCAGAGATAGAATAACCATTGCATCTGGGCTTGATGAAGAAAGCATAAAAGAAACTGCTTTAAACTCA GAAGATGTGAAAAAATATACAGATGGAAAAAATATAGTAAAAATCATAATTATAAAGGGTAGACTAGTAAATATAGTTGT AAAGTAA Protein sequence : MKVFYFIKIYKKERYLMGNYGTNIDRKWQNKWEDSNLYHFDTNNLDKKLYVLEMFSYPSGSNLHAGHWFNYGPSDSWARF KRMQGFNVFQPMGFDSFGLPAENYAIKTGVHPKDSTMKNIETMTKQLKSMGAMFHWDNEVITSEPEYYKWTQWMFLQLYK NNLAYRKNAPVNWCPSCNTVLANEQVLDGACERCSSDVIKKDLTQWFFKITDYAEELLEKLDDLDWPENTKSMQKHWIGK SIGAQLTFKIVDSDLSFDIFTTRADTLFGVTYAVLAPENPLVDKITKEDHKAEIEAYKEQAKKQSEIERQSITREKTGVF TGSYAINPINGKKVPVWVGDYVLSTYGTGAVMAVPAHDERDFEFAKKHNLPIEKVIEGGETLPYTEDGIMINSEEFNGLE SSKGRSAVVEKLEKENLGVKKINYRLRDWLVSRQRYWGAPIPIVYCDKCGTVAVPEEQLPVKLPYDVEFTPDGKSPLSKC DSFVNTTCPTCGGPAKREVDTLDTFVCSSWYFLRYADNKNSEKAFDPKIINEILPVDKYVGGPEHACMHLLYARFFTKAL RDMGYLNFDEPFSSLTHQGLILGPDGLKMSKSKGNTISPDDYIDEFGSDVFRMYLMFGFDYTEGGAWSDEGIKSVSRFVD RVERTLASCRYYINNPSDDKITIDNNEKDLNFVRHNSIKSITEDAEKMQFNTCIARLMEYTNALSKYINEDNKNSKFLKE CVEDFIILIAPFAPHFSEEQWELLGMTYSVFNEKWPQFDSKALVKDEIEIAVQVNGKIRDRITIASGLDEESIKETALNS EDVKKYTDGKNIVKIIIIKGRLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-172 | 45 |
