|
Name : secA (CTC00327) Accession : NP_781031.1 Strain : Clostridium tetani E88 Genome accession: NC_004557 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 310719 - 313244 bp Length : 2526 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : GTGAGGATGAATAAAATGAGGATTTGGGAAAAAATATTTGGCACATATAGTCAAAGAGAACTTAAAAGAGTAATTCCAAT AGTAGATAAAATAGATAAATTAGACCAAACCATGCAGAAGTTAACAGATGAAGAGTTAAAAAATAAAACAAATGAATTTA AAGAAAGATTATCAAAAGGAGAAACCTTAGATGATATATTAGTAGAAGCTTTTGCAGTAGCAAGAGAAGCTGCGTGGAGA GTTGTTAAATTAAAACCTTACAGAGAACAACTAATAGGTGGTATAATTTTGCACCAAGGTAGAATTGCAGAAATGAAAAC AGGAGAAGGAAAAACATTAGTTGCAACATTACCAGCATATCTCAATGCTCTAAAAGGAGAAGGCGTACATATAGTTACAG TAAATGATTATCTTGCAAAAAGAGATAAAGAAACTATGGGAGCTATATATGAATTCTTAGGGTTAACTGTAGGGGTTATC CTCCACGATTTAGAGCATAACGAAAGACAAGAAGCATATAATTGTGATATTACTTATGGAACCAATAGTGAACTTGGATT TGATTATTTAAGAGATAATATGGTTGTTTATAAAGAAGAGAGAGTTCAAAGGAAATTAAACTTTTCCATAGTAGACGAAG TGGATTCCATACTAATAGACGAAGCGAGAACTCCTCTTATAATATCAGGACAAGGAGAAAAGTCTACAGAGTTTTATAAA GTAGCAGACTACTTTGCCAAATCCTTAATAAAAGAAGAAGACTTTACTGTAGATGAAAAAGCTAGTGCAGTTATGCTAAC AGATAAAGGTATAGAAAAAGCAGAAGCATATTTTAAGTTGGAAAACTATGCTGATCCAGAAAATATGGAAATACAGCATC ATGTGGTTCAAGCATTAAAGGCAAACTATTCCATGAAAAAAGATACAGATTACATGGTAAGAGATGGGGAAGTATTAATA GTAGATGAGTTCACAGGAAGAGTTATGGACGGTAGAAGATATAGTGATGGTCTTCACCAAGCTATTGAAGCTAAAGAAGG CGTAAATGTAGAAAGAGAATCAAAAACTCTAGCAACTATAACTTATCAAAATTTCTTTAGAATGTATGATAAATTATCTG GTATGACAGGTACAGCACAAACAGAAGAAGTAGAATTTAGAGAAATATACGGACTAGACGTTGTAGTTATACCTACTCAT AAACCAGTTTTAAGAATAGATAATTCTGATGTAGTTTATAAATCAGAAAAAGGAAAATATATGGCCATAGTTGATGAGAT TGTAGAAACTCATAAAAAAGGTCAGCCAGTGCTTGTGGGTACTGTTAGCATAGAAAAATCTGAGCTTATATCAGAAATGC TTAAAAGAAAAGGAGTACCACATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCAGAAATAGTATCCCATGCTGGG GAATATGGTATGGTTACTATTGCAACAAATATGGCAGGACGTGGTACTGACATTAAGCTTGAAGAAGAGGTAATTAAGGC TGGTGGATTAAAGATAATAGGAACAGAAAGACATGAATCCAGAAGAATCGATAATCAATTAAGAGGACGTTCAGGACGTC AAGGGGATCCTGGAGCATCTAGATTCTATGTTTCATTGGAAGATGATTTAATGAGAATATTTGGTTCTGATAAACTAAAA GGTATAGTTGAAAAACTAGGACTTGGTGATGATGAAGCTATAGAAAGTAAAATGGTAAGCAATGCTATAGAAAATGCACA AAAGAAAGTTGAAGGAAATAACTTTGACATAAGAAAGACATTAATTCAATATGATGATGTTATAAATAAACAAAGAGAAA TAATTTATAAACAAAGATCTGAAGTATTAGAAGGTGCAGACTTGAAAGATCAGATACAAGAGATGATAAGAGATGTTATA AACTCAGTTGTAGATTCTCATATATCTGATATAGAAGAAGAGTTTAAAGAAGAACTTGATAAACTTATTAAGTTTTTAGA AGATATATTCTTGCCTAAAGACTATATAAAAGTAGAACACTTAGAAAATTTATCTAATGATGAAATAAAAGAAAAATTAT ATGATATAGCTAAAAATATATACACAGATAAAGAAGAAGAATTTGAATCAGAACAAATGAGAGATATAGAAAGAGTTATT CTTTTAAGGGTAGTAGACACTAAGTGGATGGATCATATTGATAATATGGATCACTTAAAGCAAGGTATAGGCTTAAGAGC ATATAAACAACAAGATCCAGTTCAAGCGTATCAATTTGAAGGAAGTCAAATGTTTGACGAAATGATATATAATATAAAAG TTGATACAGTTAGATATTTATTTAGAGTGCAAATAGAGAAAGCTCCAGAAAGGGAACAAGTTGCAAAGGAAACTTCAACT AACCAAGGTGGAGATGATACATTAAAAAAACAGCCTATAAAAAAAGAGCCTAAGATAGGTAGAAATGATCTATGTCCTTG TGGTAGTGGGAAGAAATATAAAAATTGTTGCGGAAGAGAAGTTTAA Protein sequence : MRMNKMRIWEKIFGTYSQRELKRVIPIVDKIDKLDQTMQKLTDEELKNKTNEFKERLSKGETLDDILVEAFAVAREAAWR VVKLKPYREQLIGGIILHQGRIAEMKTGEGKTLVATLPAYLNALKGEGVHIVTVNDYLAKRDKETMGAIYEFLGLTVGVI LHDLEHNERQEAYNCDITYGTNSELGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYK VADYFAKSLIKEEDFTVDEKASAVMLTDKGIEKAEAYFKLENYADPENMEIQHHVVQALKANYSMKKDTDYMVRDGEVLI VDEFTGRVMDGRRYSDGLHQAIEAKEGVNVERESKTLATITYQNFFRMYDKLSGMTGTAQTEEVEFREIYGLDVVVIPTH KPVLRIDNSDVVYKSEKGKYMAIVDEIVETHKKGQPVLVGTVSIEKSELISEMLKRKGVPHQVLNAKYHEKEAEIVSHAG EYGMVTIATNMAGRGTDIKLEEEVIKAGGLKIIGTERHESRRIDNQLRGRSGRQGDPGASRFYVSLEDDLMRIFGSDKLK GIVEKLGLGDDEAIESKMVSNAIENAQKKVEGNNFDIRKTLIQYDDVINKQREIIYKQRSEVLEGADLKDQIQEMIRDVI NSVVDSHISDIEEEFKEELDKLIKFLEDIFLPKDYIKVEHLENLSNDEIKEKLYDIAKNIYTDKEEEFESEQMRDIERVI LLRVVDTKWMDHIDNMDHLKQGIGLRAYKQQDPVQAYQFEGSQMFDEMIYNIKVDTVRYLFRVQIEKAPEREQVAKETST NQGGDDTLKKQPIKKEPKIGRNDLCPCGSGKKYKNCCGREV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 9e-134 | 41 |
