Gene Information

Name : CTC02530 (CTC02530)
Accession : NP_783053.1
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 2687117 - 2688313 bp
Length : 1197 bp
Strand : -
Note : catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine

DNA sequence :
ATGGATATAAAAAATATGGGATTTGGTACTAAAGCAATACATGGGGGAAATAAAAAAGATACACAGTATGGAGCATTGTC
TACACCAATATATCAGACATCAACCTTTATATTTGACTCTGCTGAACAGGGTGGAAAAAGATTTGCAGGAGAAGAAAGTG
GACATATATATACAAGACTAGGAAATCCTACAACTGGTCAATTAGAGGATAAAATGGCTATATTAGAAGGTGGAGAGGCT
GTAATAGCAACTGCATCAGGTATGGGAGCTATATCTTCAGCATTATGGACAGCTCTAAAGGCAGGGGATCATGTAGTAGC
AGGTGAAACATTATATGGATGTACATTTGCTTTATTATGCCATGGTTTACCAAGATTCGGTGTTGAAGTTACTTTTGTAG
ATACTACTAATTTAGAGGAAGTAGAAAAGGCTATAAAAGAAAATACAAAAGTAGTTTACTTAGAAACACCTGCTAATCCT
AATTTAAAGGTAGCAGATATAAAAGCTATAAGTGAAATTGCTCACAAAAAGGAAGATTGTATGGTTTTTGTAGATAACAC
TTTCTGTACACCATGTATTCAAAGACCTTTAGAGTTAGGAGCAGATGTGGTAGTTCACTCAGCTACTAAGTACTTAAATG
GACATGGAGATGTTCTTGCTGGATTTGTAGTAGGAAAGCAAGAGTTTATAAATAATGTTAGAGGTTTTGGAGTAAAGGAT
ATGACAGGATCAGTTTTAAGTCCTTTTGATGCATTCTTGGTTTTAAGAGGATTAAAAACATTAGAAATTAGAATGGAAAG
ACATTGTGCAAATGCTCAAAAAGTGGCAGAATTTTTACAAGGACATGAAGCTGTTAGTAAGGTATACTACCCAGGTTTAA
ATGATTCTGAATATTATGATATAGCTAAAAAACAAATGAGAATGCCTGGAGCTATGATTTCCTTTGAAGTTAATGGAGGT
TTAGAAGAAGGTAAAAAGATTATGGATAGTGTTAAGTTAGCTAATTTAGCTGTAAGCTTAGGGGATGCTGAAACCTTAAT
ACAACATCCAGCGTCTATGACACATTCTCCATATACTAAGGAAGAGAGAGAAGCGGCAGGCATTAGTGATAATTTAGTTA
GATTATCTGTTGGACTTGAAAATGTTGAAGATATAATTGAAGATTTAAGACAAGCGTTAGATACTATAAAAAAATAA

Protein sequence :
MDIKNMGFGTKAIHGGNKKDTQYGALSTPIYQTSTFIFDSAEQGGKRFAGEESGHIYTRLGNPTTGQLEDKMAILEGGEA
VIATASGMGAISSALWTALKAGDHVVAGETLYGCTFALLCHGLPRFGVEVTFVDTTNLEEVEKAIKENTKVVYLETPANP
NLKVADIKAISEIAHKKEDCMVFVDNTFCTPCIQRPLELGADVVVHSATKYLNGHGDVLAGFVVGKQEFINNVRGFGVKD
MTGSVLSPFDAFLVLRGLKTLEIRMERHCANAQKVAEFLQGHEAVSKVYYPGLNDSEYYDIAKKQMRMPGAMISFEVNGG
LEEGKKIMDSVKLANLAVSLGDAETLIQHPASMTHSPYTKEEREAAGISDNLVRLSVGLENVEDIIEDLRQALDTIKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 9e-57 44
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-64 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-65 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTC02530 NP_783053.1 methionine gamma-lyase BAC0207 Protein 4e-108 57