Gene Information

Name : CTC02103 (CTC02103)
Accession : NP_782664.1
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2237704 - 2240352 bp
Length : 2649 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
TTGATAGGAGAGATATTAATGCCTAAAAGGGATAAATTAGTAATATTAGATGGTAATAGTTTAATGAATAGAGCTTTTTA
TGCTTTACCACCATTAACTAACCATGAGGGAGTTCATACAAATGCAGTATATGGATTTACAAACATGCTTTTAAAAATTA
AAGATGATATAAAACCAGATTATATAGTGTGTACCTTTGATAAAAGTGCACCTACATTTAGACATCAGGCTTATAAAGAC
TATAAAGCAGGAAGAAAGAAAATGCCAGAGGAACTAAGGGAGCAGTTTCCTATAGTAAAGGGTTTGCTTTCTAAATTGGC
AATAGAAATTTTTGAAATAGAAGGCTTTGAAGCTGATGATTTAATAGGTACTTTATCTAAATTTGCAGAAGAAAAAGATA
TAGAAGTTTACATAGTAACTGGAGATAAAGATGCTCTTCAATTGGCATCAGATACTACAAAAATATTATTTACAAAGAGA
GGTATAACTGAAAGAGAAATATATGACAGACAAAAGGTAGTAGATGAAATGGGTGTTACTCCCACTGAGTTTATAGATGT
AAAAGGACTTATGGGAGATCCATCTGATAATATACCTGGAGTTCCTGGTATAGGAGAAAAAACTGCACTAAAGCTCATAA
AAGAATATAGTAGCGTAGAAAATGTATTAAATAATATAGAAAATTTAAGTGGTAAAAAATTAAAAGAAAATTTAATAGAA
AATAGTGAACAGGCTATATTTAGTAAAAAACTAGCTACTATTATGAGAAATGTTCCAATAGACATAGATTTGGAAAAAAT
TAAATCTAAAGAAGAATATGATATAGAAGCAGTAAGAGAAATATTTATAAAACTTCAATTTAAGTCTTTAATAGATAAAA
TACCTAAAGGTGAAAATCATAAAGAAGTAGAAGAGGAAGAAGAGCTAGTATATGAAGAAATTCATACTATAGAAGATTTA
ATTAAATTGTGTACTGAAATAGGAAATAAAGATGAAAAAATATATGTAAATTTTAAAAGCACTGATACAAGTTTATATTC
TAAAATATCTTTAGAAAAACTATATATATTATTTAAAAATAAGTGCTATGTAGTTAATATAGAAGAAAGAATTGAAGAAA
ATAAAGATAAAACCATAGAAATATTAAAAACTATTTTTGAAAAAGAAGCCGTAAGAGTAGTAAGTCATGATGTAAAAGTT
CTGTCTATGGCTCTTAAAAAATTAGATGTTGAATTTACTAAAGCTTTATTTGATTTGAAAATAGCAGCATATCTTATAGA
TTCTTCAAAGTCAGATTATGACTTGTCCACATTAATACAAGAATGTTTAAGTAAAATAGTAAAAGATGATGAAGAAAGAG
AAATAAGAGAAACTTCATTGTTAGAAAAATTATGTGCAAACTTAAAAGAGCAAATTATTAATTTGGAAATGGAAAAACTT
TATTATGAAGTAGAGCTACCGCTAGCTTTTGTTTTAGCCAATATGGAATTAGAAGGTTTTAAAGTAGATGGAGAAATGCT
AGAAAATATAGGCAAAAAGCTTCAGAGGGAGATAGAAAAAGTTCAAAAGGAAATATATGAACTAGCTGATGAAGAATTTA
ATGTAAATTCACCAAAACAATTAGGAAAAATTTTATTTGAAAAATTAGATTTACCTGTTATAAAGAAGACAAAAACAGGA
TATTCCACTAATGCACAAGTCTTAGAAGTCTTAGAGGATAAACATCCTATTATAAGTAAAATAGGTTACTATAGACAACT
TACAAAACTATATTCAACTTATGTAGAAGGATTAAAAAATGTTATAGATGAAGATGGAAGAATACATTCAAGCTTTAATC
AAACTGTAACAACTACAGGGAGACTTTCAAGCACAGAGCCTAATCTTCAAAATATACCTATAAAATATGAAATGGGAAGA
GAAGTAAGAAAGGTATTTGTACCAAATTATGAAAATAGTATTATACTATCAGCGGATTATTCTCAAATAGAATTAAGAGT
TCTTGCACACATAGCAGATGATGAAAACTTAATAAATGCATTTAAGCATCATGCAGATATACATACAAAAACTGCATCAG
AAGTTTTTAAAGTACCAATAGATGAAGTAACAGTTAACATGAGAGGAAATGCTAAGGCAGTAAACTTTGGAATAGTTTAT
GGAATAGGAGATTTTAGTTTAGCTAAAGACTTAAAAATATCTAGAAAAGAAGCAAAGGGGTATATAGATACTTATTTTGA
AAGATATCCTAATGTTAAAAAATATATGGATGAAACTATAGATAAAGCTAAAAGAGATATGTATGTTACAACAATTTTAA
ACAGAAGAAGATTCATACCTGAAATAGGGAATAAAAACAAAATAGTAAAGGCTTTAGGGGAAAGATTAGCCATGAATACA
CCTATTCAAGGAAGTGCCGCTGATATAATAAAAATGGCTATGGTAAAAGTCTTTAATGTACTTAAAGAAAGAGATTTAAA
AAGTAAAATAATATTACAAGTTCACGATGAGCTTATATTAAATGTTTATAAAGATGAATTAGAAGAAATTAAAAGTATAG
TCAAAGACTCTATGGAAAATGTATTACCACTTAGTGTACCACTTGAAGTTGATATAAATGAAGGAGAAAATTGGTATGAT
GCTAAGTGA

Protein sequence :
MIGEILMPKRDKLVILDGNSLMNRAFYALPPLTNHEGVHTNAVYGFTNMLLKIKDDIKPDYIVCTFDKSAPTFRHQAYKD
YKAGRKKMPEELREQFPIVKGLLSKLAIEIFEIEGFEADDLIGTLSKFAEEKDIEVYIVTGDKDALQLASDTTKILFTKR
GITEREIYDRQKVVDEMGVTPTEFIDVKGLMGDPSDNIPGVPGIGEKTALKLIKEYSSVENVLNNIENLSGKKLKENLIE
NSEQAIFSKKLATIMRNVPIDIDLEKIKSKEEYDIEAVREIFIKLQFKSLIDKIPKGENHKEVEEEEELVYEEIHTIEDL
IKLCTEIGNKDEKIYVNFKSTDTSLYSKISLEKLYILFKNKCYVVNIEERIEENKDKTIEILKTIFEKEAVRVVSHDVKV
LSMALKKLDVEFTKALFDLKIAAYLIDSSKSDYDLSTLIQECLSKIVKDDEEREIRETSLLEKLCANLKEQIINLEMEKL
YYEVELPLAFVLANMELEGFKVDGEMLENIGKKLQREIEKVQKEIYELADEEFNVNSPKQLGKILFEKLDLPVIKKTKTG
YSTNAQVLEVLEDKHPIISKIGYYRQLTKLYSTYVEGLKNVIDEDGRIHSSFNQTVTTTGRLSSTEPNLQNIPIKYEMGR
EVRKVFVPNYENSIILSADYSQIELRVLAHIADDENLINAFKHHADIHTKTASEVFKVPIDEVTVNMRGNAKAVNFGIVY
GIGDFSLAKDLKISRKEAKGYIDTYFERYPNVKKYMDETIDKAKRDMYVTTILNRRRFIPEIGNKNKIVKALGERLAMNT
PIQGSAADIIKMAMVKVFNVLKERDLKSKIILQVHDELILNVYKDELEEIKSIVKDSMENVLPLSVPLEVDINEGENWYD
AK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 2e-162 43