Gene Information

Name : CTC01894 (CTC01894)
Accession : NP_782472.1
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Resistance
Product : arsenical pump-driving ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.1.-
Position : 2013854 - 2015623 bp
Length : 1770 bp
Strand : +
Note : -

DNA sequence :
GTGATGAAATTTATGTTTGAACAATTTAATGCTGATAAATTAGATTTAACAAAATATTTATTTTATACTGGAAAAGGTGG
AGTTGGTAAAACATCTATAGCTTGTGCTACCGCTGTTAGTCTTGCTGATTCTGGTAAAAAGGTTTTATTAATTAGTACAG
ATCCTGCTTCAAATTTGCAAGATGTTTTTCATACAGAATTGAGCAACAAAGAAACTAAAATAAAAGAAACACCCAATTTA
TCTGTAGTTAATTTAAATCCAGAAGAAGCTGCAAGGGAGTACAGAGATTCTATGATTAATCCATATAAAGGAAAGCTTCC
AGAAGCCGTTCTTAAAAATATGGAAGAGCAATTATCTGGTTCTTGTACAGTAGAAATTGCAGCATTTAACGAATTTTCAA
ATTATCTTACAGATAAAAACATTGAAAATGAATATGAATTCATTATATTTGATACTGCTCCCACAGGGCATACACTTAGA
ATGCTACAATTACCATCTGCATGGACTAATTTTATCAGTGAAAGTACACACGGGGCTTCTTGTCTAGGACAACTTTCAGG
ACTTGAAGACAGAAAAGAAATGTATAAAGAAGCAGTTCAAACATTGGCAAATGGTAAACTTACAACACTTATACTAGTTG
CTAGACCTGAGAGTTCAACTCTTTTAGAAGCTGAGAGAGCATCTGATGAGTTAAGTCAATTAGGAATCAATAATCGAATG
TTAATAATAAATGGAGTGATGCAAACAGTAAATAAAGATGATGAAGTTTCTTTAGAATTTTATAATAAACAACAAAGTAC
TTTAAAAAATATTCCAAATGCTATAAAAGATATTAAAACTTATGCTGTTCCTTTACGTTCTTACAATGTATCTGGGATAG
ATAGTATTAGAATGATGTTAAAAGGTGATAGTGAAGTAATAACAACAGAAACGCTTGATAATATTGACTTTCCATCGATA
AATGATTTAATAAATGATTTATATAAATCTAAGAAAAAAGTTATTTTCACCATGGGAAAAGGTGGAGTTGGTAAAACTAC
AGTTGCCTCTACTATTGCACTAGCCCTTTCTCAAAAAGGTGTAAAAGTACATCTTACAACCACAGACCCCTCTAATCACA
TTAAATATATTATGGGCAAACATAAGAATATCACAATAAGTGAAATAAATGAACAAGAAGAATTAAAGAAATATCAAAAT
GAAGTTATTTCTAAAGCATCAGAGACAATGAGTGGTGAAGATCTAGAATATATAAAAGAAGATTTACGTTCACCTTGTAC
ACAGGAAATAGCTGTTTTCAGAGCTTTTGCCGAAATAGTAGAAAAAGCTGATGATGAAGTTGTTGTAATAGATACAGCTC
CTACTGGTCATACACTTTTACTTTTAGATTCAACTCAAAGCTATCACAAAGAAGTTGAAAGAACACAAGGTGATATTCCC
AAATCAGTTAAAAAATTATTGCCAAGACTTAGAGATGAAAATGAAACAGATGTTGTTATAGTTACATTACCCGAAGCCAC
ACCTGTTTACGAAGCAGAGCGATTAAATACTGATTTAAAAAGAGCAGGAATACACTCTAAATGGTGGGTAATAAACTCCA
GCTTGTTATTAACGGGAACAAAATCCACTTTATTACAATCAAAAGCTCAAAGTGAAATAAAGTGGATAAACGAAGTAAAT
AAATATTCTAATGGTAATTATACTGTTGTAAAATGGCTTCCAAAAGAAGTAAATGATACTACATTGCTTGAAATAATTAA
GCTGAAATAA

Protein sequence :
MMKFMFEQFNADKLDLTKYLFYTGKGGVGKTSIACATAVSLADSGKKVLLISTDPASNLQDVFHTELSNKETKIKETPNL
SVVNLNPEEAAREYRDSMINPYKGKLPEAVLKNMEEQLSGSCTVEIAAFNEFSNYLTDKNIENEYEFIIFDTAPTGHTLR
MLQLPSAWTNFISESTHGASCLGQLSGLEDRKEMYKEAVQTLANGKLTTLILVARPESSTLLEAERASDELSQLGINNRM
LIINGVMQTVNKDDEVSLEFYNKQQSTLKNIPNAIKDIKTYAVPLRSYNVSGIDSIRMMLKGDSEVITTETLDNIDFPSI
NDLINDLYKSKKKVIFTMGKGGVGKTTVASTIALALSQKGVKVHLTTTDPSNHIKYIMGKHKNITISEINEQEELKKYQN
EVISKASETMSGEDLEYIKEDLRSPCTQEIAVFRAFAEIVEKADDEVVVIDTAPTGHTLLLLDSTQSYHKEVERTQGDIP
KSVKKLLPRLRDENETDVVIVTLPEATPVYEAERLNTDLKRAGIHSKWWVINSSLLLTGTKSTLLQSKAQSEIKWINEVN
KYSNGNYTVVKWLPKEVNDTTLLEIIKLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 4e-119 48
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 1e-110 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTC01894 NP_782472.1 arsenical pump-driving ATPase BAC0030 Protein 5e-112 45
CTC01894 NP_782472.1 arsenical pump-driving ATPase BAC0571 Protein 1e-112 44
CTC01894 NP_782472.1 arsenical pump-driving ATPase BAC0572 Protein 6e-109 43