Gene Information

Name : CTC01673 (CTC01673)
Accession : NP_782272.1
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1786924 - 1788264 bp
Length : 1341 bp
Strand : -
Note : -

DNA sequence :
GTGGACTGGAGTGTTTCCATGGAGTTATTAGATTTTAATTATATAAACAAAAAAATAAAAGAAACAGATTACTACTCCTA
TGAAGGGGTTGTAAAAAAAGTAATAGGTCTAACCATAGAAGTAGAAGGAATTAAAGCTTTTATTGGAGAGGTTTGTACTA
TATATAATCAACAAAATAACCCTATAGTATGTGAAGTAGTAGGTTTTGTAGAGGATAATGTAATACTTATGCCTCTTGGA
GAATTAATTGGAATAGCTCCAGGATGTAGGGTAATACCATCAGGAAACCCTCTAAGTGTAAAGTGTTCAGAAGAGCTTTT
TGGTAAAGTATTAGATGGTCTTGGTAGTCCATTAAATGGTGAAAAAATAAAAACAGGAGTTCCCTATCCTTTGGATAGAG
AACCCCCAGACCCTTTAAAAAGAAGAAGAATAAAGGATGTAATACCAACAGGAGTAAGGGCTATAGATGGATATTTAACC
TGTGGAGAAGGACAAAGAATTGGTATATTTGCAGGTAGTGGAGTAGGAAAAAGTACAAGTCTTGGTATGATTGCAAAATA
TGCAGAGGCAGATGTAAATGTAATATGTCTAATAGGAGAAAGAGGAAGAGAAGTTCTAGATTTTGTAGAAAAGGATTTAG
GAGAAGAGGGCATGAAAAAGAGTATAGTAATTTGTGCAACCTCAGATAAACCAGCCTTGGTTAGAATAAAAGGAGCTTTT
ACAGCCACAGCTATAGCAGAATACTTTAGAGATAAGGGTAAAAAAGTAATACTTATGATGGATTCTGTTACTAGATTTGC
TATGGCTCAAAGGGAAGTAGGGCTTGCCATTGGGGAGCCACCAGCTACAAAAGGATATACACCTTCTGTATTTGCTATGC
TTCCAAGGTTAATGGAAAGATCGGGAATGTCAGATAAGGGTTCTATAACAGCTTTTTATACTGTGTTAGTAGATGGGGAC
GACTTTAATGAACCTATAGCAGATGCTGTTAGAGGTATACTAGATGGACATATTGTGTTATCCCGTGATTTAGCAGCTAA
AAACCATTATCCAGCAATTGATATTTTAAGTAGTATAAGTAGACTTATGAATGAAATTTCAGTCAAGGAGCATAAAGAAT
CTGCATCTATAGGAAGGGATTTAATTGCTACTTACAAGGAAGCAGAGGATTTAATTAACATAGGAGCTTATGTAAAGGGA
AGTAATGAAAAGATAGATATTGCAATTAAGTACATAGATAGTATAAATGAATTTTTAACCCAAAAAGTAGATGAACATAA
TAATTTTGAAGAAAGTATACAGTGGCTAAACAGTATATTTAAGAATTTAAGAAGCAACTAA

Protein sequence :
MDWSVSMELLDFNYINKKIKETDYYSYEGVVKKVIGLTIEVEGIKAFIGEVCTIYNQQNNPIVCEVVGFVEDNVILMPLG
ELIGIAPGCRVIPSGNPLSVKCSEELFGKVLDGLGSPLNGEKIKTGVPYPLDREPPDPLKRRRIKDVIPTGVRAIDGYLT
CGEGQRIGIFAGSGVGKSTSLGMIAKYAEADVNVICLIGERGREVLDFVEKDLGEEGMKKSIVICATSDKPALVRIKGAF
TATAIAEYFRDKGKKVILMMDSVTRFAMAQREVGLAIGEPPATKGYTPSVFAMLPRLMERSGMSDKGSITAFYTVLVDGD
DFNEPIADAVRGILDGHIVLSRDLAAKNHYPAIDILSSISRLMNEISVKEHKESASIGRDLIATYKEAEDLINIGAYVKG
SNEKIDIAIKYIDSINEFLTQKVDEHNNFEESIQWLNSIFKNLRSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-103 54
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-104 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-104 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-104 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-103 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-103 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-103 51
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-103 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-86 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-86 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-101 49
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-101 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-86 49
escN CAI43874.1 EscN protein Virulence LEE Protein 4e-86 49
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-85 49
escN AAC31513.1 L0034 Virulence LEE Protein 2e-85 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-85 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-85 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-85 49
escN AAK26715.1 EscN Virulence LEE Protein 1e-85 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-86 49
escN AAL57542.1 EscN Virulence LEE Protein 1e-85 49
escN YP_003223475.1 translocator EscN Virulence LEE Protein 5e-86 49
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-83 49
escN AAC38383.1 EscN Virulence LEE Protein 1e-85 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-83 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-81 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-81 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-81 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-81 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-81 49
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-79 46
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-74 45
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-77 45
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-77 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-77 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 1e-77 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 8e-78 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-75 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 7e-75 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-83 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 6e-74 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 6e-74 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 4e-68 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-68 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-68 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 4e-68 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-69 41
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-70 41
invC AAS66861.1 InvC Not tested SSR-2 Protein 6e-67 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG2144 Protein 6e-113 53
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0390 Protein 8e-103 52
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0192 Protein 1e-102 52
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0048 Protein 1e-103 51
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG2331 Protein 2e-86 50
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0812 Protein 9e-86 49
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG1254 Protein 8e-95 49
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0730 Protein 5e-86 49
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0515 Protein 8e-82 49
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG2499 Protein 2e-86 47
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG1778 Protein 1e-70 44
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG0555 Protein 2e-68 42
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG2459 Protein 2e-73 42
CTC01673 NP_782272.1 flagellum-specific ATP synthase VFG1008 Protein 2e-64 41