Gene Information

Name : fliP (CTC01662)
Accession : NP_782262.1
Strain : Clostridium tetani E88
Genome accession: NC_004557
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 1779379 - 1780164 bp
Length : 786 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence : 
ATGGAGAATAAAAGTAGCAGTAAAAGAAAAACATTCCTAGTTATAGGTATAGTTTTTTTATTAACCTTACTATGTTTTCA
ACAAAAAGCACTGGCAGCACCAGGACAAATACCTATACCTAGGATAAACATATCACCAGGAGATGGAGGAGATCCTAAAA
CCTATGTAGATAACTTGAAATTATTTTTAATGATTACTGCTTTATCTATATTACCATCTTTTATAGTAATGATGACAAGT
TTCGTAAGAATATCAGTAGTTTTTGGCTTTTTAAGAAATGCCATGGGAACGCAGCAATCTCCACCTAATCAAGTCTTAGT
AGGACTTGCTCTCTTTTTAACTATATTTATTATGACGCCAGTTTATCAAATTATTAATAAAGAAGCTATACAACCCTTTG
TAAAAAGTGAAATAAATCAAGAGCAGGCCTTTGAAACTGGATCTAAGCCTTTAAGGGAATTTATGCTAAAACAAACTAGG
GAAAAGGACTTAAAACTATTTGTAGAGATTTCAAATATAGACAAAAATATCACAAAAGAAAATGTACCTCTTTATGTAGT
GGTTCCTTCTTTTATCATAAGTGAGTTAAAAACAGCTTTTCAAATAGGGTTTTTATTATACATACCATTTTTAGTTATAG
ATTTAGTGGTAGCCAGCGTTTTAATGTCTATGGGTATGTTTATGTTACCACCGGTAATGGTATCTTTACCCTTTAAGTTA
TTACTATTTGTAATGGTAGATGGATGGCATTTACTTATAAAGTCTTTAATAATGAGTTTTAAATGA

Protein sequence : 
MENKSSSKRKTFLVIGIVFLLTLLCFQQKALAAPGQIPIPRINISPGDGGDPKTYVDNLKLFLMITALSILPSFIVMMTS
FVRISVVFGFLRNAMGTQQSPPNQVLVGLALFLTIFIMTPVYQIINKEAIQPFVKSEINQEQAFETGSKPLREFMLKQTR
EKDLKLFVEISNIDKNITKENVPLYVVVPSFIISELKTAFQIGFLLYIPFLVIDLVVASVLMSMGMFMLPPVMVSLPFKL
LLFVMVDGWHLLIKSLIMSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
XC_3016 YP_244084.1 type III secretion system protein Virulence Hrp PAI Protein 4e-36 44
hrcR NP_636600.1 type III secretion system protein Virulence Hrp PAI Protein 4e-36 44
hrcR AAP34349.1 HrcR Virulence Hrp PAI Protein 1e-35 43
hrcR NP_640757.1 type III secretion system protein Virulence Hrp PAI Protein 2e-36 43
hrcR YP_362153.1 type III secretion system protein Virulence Hrp PAI Protein 2e-36 43
hrcR AAD21321.1 HrcR Virulence Hrp PAI Protein 1e-36 43
yscR NP_456109.1 putative type III secretion protein Virulence SPI-2 Protein 9e-33 43
yscR NP_805090.1 type III secretion system protein Virulence SPI-2 Protein 9e-33 43
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 2e-33 43
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 2e-33 43
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 1e-33 43
hrcR BAB07862.1 HrcR Virulence Hrp PAI Protein 6e-35 42
hrcR YP_198720.1 type III secretion system protein Virulence Hrp PAI Protein 5e-36 42
lscR AAO18040.1 LscR Virulence TTSS locus Protein 9e-34 42
escR AAL57527.1 EscR Virulence LEE Protein 6e-34 41
escR CAC81847.1 EscR protein Virulence LEE II Protein 6e-34 41
escR CAI43889.1 EscR protein Virulence LEE Protein 6e-34 41
escR AAC31528.1 L0049 Virulence LEE Protein 6e-34 41
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 6e-34 41
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 8e-34 41
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 8e-34 41
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 7e-34 41
escR AAK26700.1 EscR Virulence LEE Protein 6e-34 41
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 7e-34 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG2338 Protein 5e-54 56
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG2494 Protein 3e-56 55
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG1259 Protein 7e-60 52
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG2016 Protein 8e-55 50
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG0519 Protein 8e-34 43
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG0394 Protein 1e-34 42
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG0044 Protein 3e-37 41
fliP NP_782262.1 flagellar biosynthesis protein FliP VFG0827 Protein 3e-34 41