Gene Information

Name : hsdM (PD2072)
Accession : NP_780246.1
Strain : Xylella fastidiosa Temecula1
Genome accession: NC_004556
Putative virulence/resistance : Virulence
Product : type I restriction-modification system DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 2454521 - 2456902 bp
Length : 2382 bp
Strand : -
Note : -

DNA sequence :
ATGCAGAAGACTCAACAAGACCAAAGCCAGATCAAGTGGATTTCCGACTTCATCTGGAACATCGCTGACAACCGCCTGCG
CGATGTCTATGTGCGCGGCAAATACCGCGACGTGATCCTGCCTTTCACTGTGCTGCGACGGCTCGACGCCGTGCTGGAAG
CCACCAAGGACGCGGTGCTGGAACGCAAAAAGTTCCTCGACGCCCACAACGTGGTCGAGCAGGATGGCGCGCTGCGCATG
GCGGCGGGTCAGGCGTTCTACAACGTCTCGGAATTCACCTTGGCCAAGCTCAAGGCCAGCGCGGCAGGGCAGCGCCTGCG
TGATGACTTCATTGCGTATCTGGACGGCTTCTCACGCGACGTGCAGGAGATCCTCACCAAGTTCAACTTCCGCAACCAGA
TCCAGAAGCTGGTGGATTCCCATGTTCTCGGCTACCTGATCGAAGACTTCCTCGACCCTGAGGTCAATCTTGCGCCGTTG
CCGGTGAAGGATGCCGACGGTCGCATCAAATTGCCCGCGCTGGATAACCACGGCATGGGCACGGTGTTCGAGGAGCTGAT
CCGTCGTTTCAACGAAGACAACAACGAAGAGGCGGGCGAGCACTTCACCCCGCGCGACGTGGTGCAGCTCATGGCCAAGC
TGTTGTTTCTGCCGGTGGCCGAGCGCATTGAGTCCAGCACTTATTCGCTTTACGACGGCAGTTGCGGCACCGGCGGCATG
CTGACCGTGGCTGAGGAAGCGCTGCACGCGCTGGCCGAGCAGCACGGCAAGGAGGTCTCCATTCACCTGTTTGGCCAGGA
GATCAGCGACGAAACCTACGCCATCTGCAAGGCCGATCTGCTTTTGAAGGGCGAAGGTGCGGAAGCTGAGAACATCGTCG
GCGGCGCGGATAAATCCACCTTGTCCGCCGACCAGTTCCCTTCGCGCGCATTCGATTTCATGATCTCCAACCCGCCCTAC
GGCAAGAGTTGGAAAACCGATCTAGATCGCATGGGCGGCAAGAAGGGGTTCAGTGACCGGCGCTTTATCGTCAGCCACGG
CGGCGATCCCGAGTTTAAGCTCCTCACCCGTTCCAGCGACGGGCAGCTCATGTTCCAGGTGAACAAGCTGCAGAAGATGA
AGCACAACACGCCGCTGGGCAGCCGCATCGCGCTGGTGCATAACGGCTCGGCGCTGTTCACCGGCGACGCGGGCCAGGGC
GAGAGCAACATCCGCCGCTGGGTGCTGGAGAACGACTGGCTCGAAGCCATCATCGCCCTGCCGCTCAACATCTTCTACAA
CACCGGCATTGCCACCTACATCTGGGTGCTGGCCAATAAGAAGGCGCAAGCGCGCCGTGGCAAGGTGCAGTTGATTGACG
CATCACAGTGGTTCCAGCCGCTGCGCCGCAACCTCGGCAAGAAGAACTGTGAACTGGGTGCTGCCGATATTGCCCGCATC
CTCGATCTCTACCTTGGCCAGACGCAGGAAGCTGCGCAGTCCAAATGGTTCGACACGCAAGACTTTGGCTATTGGAAGGT
CACCATCGAGCGCCCGTTACGCCTGAAAAGCCAGCTCTCTGACGAACGCATTGAGTCACTGCGTTTTGCCACTGGCGAGG
AGGCATTGCGTGCTGAGATCTACGCCACCCACGGCGAGGCGCTGTATACCGAGTTTGCCAAGTGCAAACCGGCCATTGAG
GCATGGCTGAAAGGCGAGGATGAGAACGAGGATGACGACAGCGACGACAGCGACAGCGGCGACGACAACGAGGCCCCCGC
CGCCCGCAAAGCTGTGCCCGTCAAGCGCCGCAAAAAGCTGCTTGATGCATCGACGTGGCAGCGCGACAAAGCACTGATGG
AGGTGGCGCAACGGGCGCAGCAGGCATTGGGCCGCGCCGTGTTCGACGACCACAATGCGTTCTGCGTCGGCTTCGATGCA
GTGTGCAAGGCGCAGGACGCACGCTTAAGCGCGCCAGAGAAGAAGGCCATCTACAAGGCGGTGAGCTGGCGCGATGACGC
CGCACTGCCGGTCATCGCCAAGCGCAGTAAGCTCAAGGCAGGCGAATGCTTCGAGCCCGGCTTTGATGGCGCGTATCTGG
AAACCGTGGGCAAGGATCGCTTCATGGTCGAGTACGAACCAGACAGCGCGCTGCGCGATACCGAGCAGGTGCCGTTGCAG
GAACCAGGCGGCATTGATGCCTTTTTTGCCCGCGAAGTGCTGCCGCACGCGCCGGATGCCTGGATCGCCACGGACAAGAC
TCAGATTGGCTACGAGATTTCGTTTGCTCGCTATTTCTACAAGCCCGTGCCGTTGCGGACGCTGGCGGACATCCGCGCGG
ACATCCTTGCGCTGGAGCAGCAGACGGAAGGGTTGTTGCATAAGATTGTGGGGAACGTGTGA

Protein sequence :
MQKTQQDQSQIKWISDFIWNIADNRLRDVYVRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFLDAHNVVEQDGALRM
AAGQAFYNVSEFTLAKLKASAAGQRLRDDFIAYLDGFSRDVQEILTKFNFRNQIQKLVDSHVLGYLIEDFLDPEVNLAPL
PVKDADGRIKLPALDNHGMGTVFEELIRRFNEDNNEEAGEHFTPRDVVQLMAKLLFLPVAERIESSTYSLYDGSCGTGGM
LTVAEEALHALAEQHGKEVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLSADQFPSRAFDFMISNPPY
GKSWKTDLDRMGGKKGFSDRRFIVSHGGDPEFKLLTRSSDGQLMFQVNKLQKMKHNTPLGSRIALVHNGSALFTGDAGQG
ESNIRRWVLENDWLEAIIALPLNIFYNTGIATYIWVLANKKAQARRGKVQLIDASQWFQPLRRNLGKKNCELGAADIARI
LDLYLGQTQEAAQSKWFDTQDFGYWKVTIERPLRLKSQLSDERIESLRFATGEEALRAEIYATHGEALYTEFAKCKPAIE
AWLKGEDENEDDDSDDSDSGDDNEAPAARKAVPVKRRKKLLDASTWQRDKALMEVAQRAQQALGRAVFDDHNAFCVGFDA
VCKAQDARLSAPEKKAIYKAVSWRDDAALPVIAKRSKLKAGECFEPGFDGAYLETVGKDRFMVEYEPDSALRDTEQVPLQ
EPGGIDAFFAREVLPHAPDAWIATDKTQIGYEISFARYFYKPVPLRTLADIRADILALEQQTEGLLHKIVGNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 2e-147 45
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 2e-147 45
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 3e-147 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hsdM NP_780246.1 type I restriction-modification system DNA methylase VFG1102 Protein 9e-148 45