Gene Information

Name : alr (PD1823)
Accession : NP_780007.1
Strain : Xylella fastidiosa Temecula1
Genome accession: NC_004556
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 2127646 - 2128743 bp
Length : 1098 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
GTGTGCTCCGTGCGTCCCGCCCACGCCGTAATTGATCTGGATGCGTTACGTCACAATTATCGATTTGCTCGCCGTCTTGG
CGGTGGCAAGGCGTTAGCTGTGGTGAAAGCCGATGCGTATGGTCACGGTGCGGTGCGTTGTGCGCAGGCTTTGGAGGCTG
AAGTTGATGGTTTTGCGGTGGCGTGTATCGAAGAGGCGTTGGAGTTACGCCAAGCCGGTATCCAGGCACCGATCCTGTTG
CTGGAAGGATTTTTCGAGGTTGAAGAGCTGGAATTGATTGCTAAGCACAATTTATGGACTGTGATTGCTTCGTCCTGGCA
GGTGCGGGCGTTGGCTGCGTTCCACAGTCCATCTCCAATTGGGGTGTGGCTTAAGTTGGATAGTGGCATGCATCGGCTTG
GTTTGGAGCCAAAGGAGTTTCGTGATGCTTGGATGTCTCTGCATAGTCTGCCGCAGGTGGGCGAGGTCGTCTTGATGACG
CATTTGGCCCGTGCTGATGAGTTGGATAATCCTCGTACCAATGAGCAGGCATCGGTTTTTGCACATGCTTCGCAGGGAAT
GGTGGCGCCAGCAAGTGTGTGTAACTCTTCAGGTTTGCTTGGTTGGGCAGGGTTGTACAGTGATTGGGGTCGGCCCGGGT
TAATGTTGTACGGTGTCAATCCTATTTCGCAGGAGAGCACGTCACTTAGTGGGCCATTGCGTCCTGTGATGATGGTGTAT
TCCAAGCTGATTGCGGTACGCGAGTTGCCTGCCGGCGAGCCAGTTGGCTATGGGGCATCCTTTGTCACTGAGCGGCCAAC
CCGGGTTGGTGTGGTAGCGATGGGCTATGCAGACGGTTACCCGTATTTTGCGGTCAATGGTACGCCGCTCTTGGTTGATG
GGCGTGTTTGTCCGTTGATCGGCCGGGTTTCTATGGACATGTTGACGGTTGATCTGACAGACCATCCGCAGGCGGATGTT
GGCAGTCAAGTGCAATTGTGGGGTGTGCAACCGGGTGTGGCTGAACTTGCGGCACATTGTAATTTGAGCGCTTATCAGTT
GTTGTGCGGTCTTAAGCGTGTACGTCGATACTATTTGGGTGAGATGGGCGCAGTGTGA

Protein sequence :
MCSVRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACIEEALELRQAGIQAPILL
LEGFFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVWLKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMT
HLARADELDNPRTNEQASVFAHASQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVY
SKLIAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRVSMDMLTVDLTDHPQADV
GSQVQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMGAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 1e-52 42