Gene Information

Name : metB (PD1812)
Accession : NP_779997.1
Strain : Xylella fastidiosa Temecula1
Genome accession: NC_004556
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2116534 - 2117736 bp
Length : 1203 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGAGCATTCATGATGTGCACGAAGGCACGTGTCACGTGACCACTTCCGCGGTGCGTGCTGGGATCGATTCCGACACTGC
TCATGGGGCAGTGACGCCACCGATTGTGCTTTCATCCAACTTCTCGTTTGAACGTTTCGGTCATAAGCGTAAGTACGATT
ACACACGTAGTGCTAATCCAACGCGGGATCTGCTCGGCGAGGCGCTTGCGGAGTTGGAGGGGGGTGCCGGTGGTGTGGTT
ACGGCGACTGGGATCGCTGCGATTACGTTGGTGTTGCACGCATTGCTCCGGCCGGGTGATCGTTTGGTTGTGCCACATGA
TGCTTACGGTGGCAGTTGGCGTTTGTTCAATGCGTTGGCTCAAAAGGGACATTTTGAATTGATCACTGTCGATTTGACGG
ATGCACGATCACTGGTTGAGGCATTGGCACTACCACCGAAGTTGGTATTGATCGAAACTCCTTCCAATCCATTGTTACGT
ATTACTGATTTGGGTGCGGTGATTGAGGCAGCGCACCGTGTCGGTGCTTTGACTGTGGTCGACAATACGTTTATGTCTCC
GGTGTTGCAGCGTCCTTTAGAGTTCGGCGCTGACTTGGTATTGCATTCGACCACGAAGTACATCAATGGCCACAGTGATG
TTGTCGGTGGCGTTGTTGTGGCACGTGATGTTGCGCACTATCAGCAGTTGGTGTGGTGGGCGAATGCGCTGGGTCTGACC
GGCTCGCCATTCGATGCCTTCTTGACGTTGCGGGGGGTGCGCACGCTGGATGCGCGTTTGCGTGTGCATCAGGAGAATGC
GCAGATGATTGCAGCCTTACTGGAGGGGCATGGTGTGGTGAAGCACGTGCATTACCCAGGATTAGCTTCGCATCCGGGGC
ATGTGCTGGCGGGGCGGCAGCAAAAAGGGTTCGGTGCCATGCTCAGTTTCGAGTTGCAGGGTGGGGAAGAGGCGGTGCGG
GCTTTTGTCAGTGGCTTGCGTTATTTCACGCTGGCTGAGTCGCTGGGTGGGGTTGAGAGTTTGATCGCTCATCCGGCTTC
GATGACGCATGCTGCCATGACGCCCGAGGCGCGTGCTAAAGCGGGTATCTCTGATGGGTTGTTGCGCTTGTCGGTGGGGA
TTGAGGCCAGTGAGGATTTGATCGTTGATCTGGTGGCTGGTTTGGGGCGTGCTCAGGCGGTGCGGGAAGAGTGCAAGGTG
TGA

Protein sequence :
MSIHDVHEGTCHVTTSAVRAGIDSDTAHGAVTPPIVLSSNFSFERFGHKRKYDYTRSANPTRDLLGEALAELEGGAGGVV
TATGIAAITLVLHALLRPGDRLVVPHDAYGGSWRLFNALAQKGHFELITVDLTDARSLVEALALPPKLVLIETPSNPLLR
ITDLGAVIEAAHRVGALTVVDNTFMSPVLQRPLEFGADLVLHSTTKYINGHSDVVGGVVVARDVAHYQQLVWWANALGLT
GSPFDAFLTLRGVRTLDARLRVHQENAQMIAALLEGHGVVKHVHYPGLASHPGHVLAGRQQKGFGAMLSFELQGGEEAVR
AFVSGLRYFTLAESLGGVESLIAHPASMTHAAMTPEARAKAGISDGLLRLSVGIEASEDLIVDLVAGLGRAQAVREECKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-44 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-48 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-50 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB NP_779997.1 cystathionine gamma-synthase BAC0207 Protein 1e-45 42