Gene Information

Name : guaA (PD1447)
Accession : NP_779642.1
Strain : Xylella fastidiosa Temecula1
Genome accession: NC_004556
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1686163 - 1687731 bp
Length : 1569 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACACCGAATATTCATCACGACAAAATTCTTATCCTCGATTTCGGCGCACAGTACACCCAGTTGATTGCCCGTCGTAT
CCGTGAAATTGGTGTCTACTGCGAAGTGTGGCCCTGGGATCACTCCCCTGAAGAGATTCTGAGCTTCGGGGCCAAAGGTA
TCATCCTCTCCGGTGGCCCTGAATCGACCACATCCCCGGGTGCGCCTGCAGCACCGCAGCACGTCTTTGATAGTGACTTA
CCAATCTTCGGTATTTGCTATGGCATGCAAACCATGGCCGTACATCTTGGGGGTGCGACCGAGGCAGCCGACAAACGCGA
GTTTGGTCATGCCTCGGTCCAGGTGATTTACCCGGATACCTTGTTTTCCGGCTTGTCCGATCATCCCTCTGAGTTCCGTC
TGGATGTGTGGATGAGTCATGGTGACCATGTTTCACGCGTCCCGCCCTGCTTCACCATTACAGCCGCCACTGACCGCATC
CCCATTGCGGCGATGAGTCGCGAGGATAAGCGCTGGTATGGCGTGCAATTCCATCCGGAAGTGACCCATACCTTACAGGG
ACAGGCTTTATTGCGCCGTTTTGTGGTTGATATATGTGGCTGTCAGACGTTATGGACCTCCGCTAACATTATTGAAGACC
AAATCGCTCGTGTGCGTGAACGTGTCGGTTGCGATGAAGTCATTCTCGGCCTGTCTGGTGGCGTTGATTCTTCCGTCGTC
GCCGCACTTTTACACAAAGCCATTGGCAGCCAACTGACGTGTGTATTTGTTGATACTGGCATGCTTCGCTGGGGAGAAGG
CGACCAAGTGATGGCCATGTTTGCGGAACATATGGGCGTCAACGTGGTACGTATCAATGCGGCATCGCGTTACTTCGACG
CACTGCAAGGTGTCTACGACCCAGAAGCCAAACGCAAAATCATCGGCAACCTGTTCATCCAGATATTCGAGGAAGAGGCC
AGCAAACGAAAGCAGGCCAAATGGTTGGCCCAAGGCACGATTTATCCTGATGTGATCGAATCGGCCGGCAGCAAAACCGG
CAAAGCCCACGTAATCAAAAGCCATCACAACGTCGGCGGCTTGCCGGAGCAGATGACCCTGGGTATGGTCGAACCATTAC
GTGAATTGTTCAAAGATGAAGTGCGCCGCCTTGGCGTTGCACTGGGCCTGCCCCATGCCATGGTATATCGCCATCCATTC
CCAGGACCTGGCTTGGGCGTGCGTATCCTTGGTGAAGTCAAGCCGGAGTATGCCGAGTTACTGGCCAAGGCTGACTCGAT
TTTTATTGATGAACTTCATCAAGCCGACCTGTACGACAAGGTCAGCCAAGCCTTTGCAGTCTTTCTTCCGGTGAAATCAG
TTGGCGTTGTTGGTGATGCCCGTGCGTACGAATGGGTGATTGCACTGCGCGCGGTTGAGACCGTTGATTTTATGACGGCA
CACTGGGCACCACTGCCGTATGACTTCCTGAGTACCGTCTCCAACCGCATCATCAATGAACTACGCGGCGTGTCCCGCGT
TGTCTACGATATTTCCGGAAAACCGCCAGCCACGATTGAGTGGGAGTGA

Protein sequence :
MTPNIHHDKILILDFGAQYTQLIARRIREIGVYCEVWPWDHSPEEILSFGAKGIILSGGPESTTSPGAPAAPQHVFDSDL
PIFGICYGMQTMAVHLGGATEAADKREFGHASVQVIYPDTLFSGLSDHPSEFRLDVWMSHGDHVSRVPPCFTITAATDRI
PIAAMSREDKRWYGVQFHPEVTHTLQGQALLRRFVVDICGCQTLWTSANIIEDQIARVRERVGCDEVILGLSGGVDSSVV
AALLHKAIGSQLTCVFVDTGMLRWGEGDQVMAMFAEHMGVNVVRINAASRYFDALQGVYDPEAKRKIIGNLFIQIFEEEA
SKRKQAKWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEQMTLGMVEPLRELFKDEVRRLGVALGLPHAMVYRHPF
PGPGLGVRILGEVKPEYAELLAKADSIFIDELHQADLYDKVSQAFAVFLPVKSVGVVGDARAYEWVIALRAVETVDFMTA
HWAPLPYDFLSTVSNRIINELRGVSRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-122 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-122 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-122 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-110 48