Gene Information

Name : thyA (PD1364)
Accession : NP_779562.1
Strain : Xylella fastidiosa Temecula1
Genome accession: NC_004556
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1586715 - 1587509 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGAAGCAGTACCTTGAATTACTGAATGATGTGCTTGTGCATGGCATAAAAAAGCCTGACCGCACTGGCACGGGGACACG
CAGTGTGTTCGGTTGGCAGATGCGATTTGACTTGAGCCAAGGTTTTCCACTCGTTACGACTAAAAAGCTGCATTTGCGTT
CGATCATTCACGAGTTGCTATGGTTTCTCAGGGGGGAAACCAATATTGCTTATCTTAAGAAGCATCAGGTACACATCTGG
GACGAGTGGGCCGATGCCACGGGTGAGTTGGGACCTGTTTACGGCAAGCAATGGCGCCGTTGGGCTGGTGCGGATGGTCA
CGAGATCGACCAGATCCGTTGGTTGGTGGAGGAGATCAAGCGTAATCCAGATTCGCGCCGCTTGGTGATTAGTGCTTGGA
ATGTGGCTGATCTTCCACAGATGGCTTTGGTGCCGTGCCATGCACTGTTTCAATTCTATGTTGCCAATGGCAAATTGAGC
TGTCAGCTCTATCAACGTAGCGCTGATATTTTTCTTGGCGTCCCTTTCAATATCGCTAGTTATGCACTGCTCACCCATAT
GTTGGCTCAGGTGACTGGGCTCGTGGTCGGTGATTTTGTGCATACGTTGGGTGATGCACATTTGTATGCTAATCATGTCG
AGCAAGCATCCGTGCAACTGGGGCGTGTGCCGCGACCGCAACCGGTATTAAGGCTTAATCAGGCAGTGACTGACTTGTTC
GACTTTACCTACGATGACATTGTGATTGAAGGTTACGATCCATATCCGGCTATCAAGGCACCGGTGGCTGTGTGA

Protein sequence :
MKQYLELLNDVLVHGIKKPDRTGTGTRSVFGWQMRFDLSQGFPLVTTKKLHLRSIIHELLWFLRGETNIAYLKKHQVHIW
DEWADATGELGPVYGKQWRRWAGADGHEIDQIRWLVEEIKRNPDSRRLVISAWNVADLPQMALVPCHALFQFYVANGKLS
CQLYQRSADIFLGVPFNIASYALLTHMLAQVTGLVVGDFVHTLGDAHLYANHVEQASVQLGRVPRPQPVLRLNQAVTDLF
DFTYDDIVIEGYDPYPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 3e-78 60