Gene Information

Name : pyk (CAB645)
Accession : YP_220043.1
Strain : Chlamydophila abortus S26/3
Genome accession: NC_004552
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 742818 - 744263 bp
Length : 1446 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCAAGAACGAAAATCATTTGTACTATAGGTCCAGCAACAAATACTCCGGAAATGCTCGAGAAGCTGTTAGACGC
GGGTATGAACGTCGCCAGGTTAAATTTTAGTCATGGTACTCATGAAAGTCATGGTCAGACAATCAGTCTTCTTAAAGAGT
TGCGAGAGAAAAAAGGAGCGCCTTTAGCGATTATGTTGGACACTAAAGGTCCAGAAATTCGTTTAGGCAAGATTCCCACG
CCCATTCAGGTGTCACGAGGTCAGAAAATCACTTTATTAGAGAAAGAGATCGAGGGCTCTCTCGAAGGGGGAGTCACTTT
ACATCCTCAATGCGTATTCCCTTTTGTGCGTGAAGGTACTGATGTTTTGATCGACGATGGGTATCTCCAAGCTGTTGTCA
CTTCTGCTGGTAACGATTGGTTAGAGTTAGAATTTATTAATTCTGGAGAGCTGAAGTCTCATAAGTCTTTAAGTATCAGA
GAAATTGATTTAGCTCTTCCTTTCATGACCGATAAGGATATCCATGATCTTAAATTTGGAGTCGATCAGGGGGTTGATGT
TATTGCGGCTTCCTTTGTGCGCTGTGCTGAAGATATCGAGAGCATGCGCAAGTGCTTAGCAGATTGCGGGCGTGGGGATA
TGCCGATTATTGCGAAAATAGAAAATCGCCTAGGTGTAGAAAATTTCCCTCAGATTGCCAAAGTTGCGGATGGGATTATG
ATTGCCCGTGGGGATTTAGGAATCGAGCTGTCTGTTGTGGAACTTCCTAGTTTGCAAAAATTTATGGCGAAGATCTCTCG
TGAAACAGGGCGTTTTTGTATTACTGCTACACAGATGCTAGAATCGATGATTCGCAATGTATTGCCAACGCGTGCGGAAG
TTTCAGATATAGCAAACGCTATTTATGATGGGACATCTGCAGTGATGTTATCAGGAGAAACGGCTTCGGGTAGTCATCCT
ATAGCTGCTGTGAAAATTATGCGTTCTGTAATTCAAGAAACGGAAAAAAATCTCAACTATATGTCTTTCCTAGAGATTAA
TGATAGTGAGAGTGCTGTTAAGGTATCTCCTTATCTTCAGTCTATAGGGCTGTCAGGAATTCAAATTGCAGAGAAGGCAG
CAGCGAAAGCCATTATCGTGTATACAGAATCCGGAGGCTCTCCGATCTTCCTTTCTAAGTATCGTCCACGCTTCCCCATT
ATTGCTGTTACACCAAATCTATCTGTATACTACCGACTTGCTTTAGAGTGGGGGGTATACCCTATGCTTACTGAAGAGTC
GGATCGTACAGTCTGGAGACATCAAGCTTGTGTCTATGGTATCGAAAGAGGAATTTTATCAAATTACGATAAGGTCCTAG
TGTTAAGCCGCGGAGCACAAATGAAAGATACCAATAATCTGACATTGACAACAGTAAATGATATCATCTCAGCATCAGCC
AAATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGQTISLLKELREKKGAPLAIMLDTKGPEIRLGKIPT
PIQVSRGQKITLLEKEIEGSLEGGVTLHPQCVFPFVREGTDVLIDDGYLQAVVTSAGNDWLELEFINSGELKSHKSLSIR
EIDLALPFMTDKDIHDLKFGVDQGVDVIAASFVRCAEDIESMRKCLADCGRGDMPIIAKIENRLGVENFPQIAKVADGIM
IARGDLGIELSVVELPSLQKFMAKISRETGRFCITATQMLESMIRNVLPTRAEVSDIANAIYDGTSAVMLSGETASGSHP
IAAVKIMRSVIQETEKNLNYMSFLEINDSESAVKVSPYLQSIGLSGIQIAEKAAAKAIIVYTESGGSPIFLSKYRPRFPI
IAVTPNLSVYYRLALEWGVYPMLTEESDRTVWRHQACVYGIERGILSNYDKVLVLSRGAQMKDTNNLTLTTVNDIISASA
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-58 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-58 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-58 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-57 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_220043.1 pyruvate kinase VFG0479 Protein 2e-58 43