Gene Information

Name : CAB569 (CAB569)
Accession : YP_219970.1
Strain : Chlamydophila abortus S26/3
Genome accession: NC_004552
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 644927 - 645691 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGGAAGAACAGACATTTATCAGTAAGAAGGTGGGAGTTTTACCAGCGAGATGGGGTAGTGTAAGATTTCCTGGGAAACC
CTTAGCCATGATCCTGGGAAAGTCCTTAATCCAAAGAACTTACGAAAATATCATCCAAAGCGAAACACTAGATAAAGTAG
TTGTAGCTACTGATGATCAACGCATTATGGATCACGTTCTAGATTTTGGTGGTGCGTGTCTGATGACGAGTCCAGAGTGC
GCTAATGGTACCGAACGTATGGCGGAAACCGTATCGCGTTATTTCCCTGAGGCTGAGATTATGGTGAACATCCAAGGAGA
TGAGCCCTGTTTACGCCATACTGTTGTCGATGCCCTTGTAAGAAAACTGGAAGAGCATCCAGAAATTCAAATGGTGACTC
CCGTGGCCCAAACCACAGATTCTCATGAAATCTTAACAAATCAAAAAGTAAAATGTGTTTTCGATAAAAATGGAAAGGCT
TTATATTTTAGCAGGAGCCCTATTCCACACATTTTAAAGAAAGAAACACCAATTTATCTACATATTGGCGTGTATGCATT
TAGAAGATCTGCTCTGTTCAGTTACATTGCTTCCGCTCCTTCTCCTCTAAGTCAAGCTGAAGATCTTGAGCAACTACGTG
TACTAGAACACGGTGGATCCATTCATGTATGTGTAGTGGAAGCTAAGAGCCCTTCGGTGGATTATCCAGAAGATATCAGT
AAGGTGGAAGAATACTTAACATGTCATTCAAGTGCATCTTTTTAA

Protein sequence : 
MEEQTFISKKVGVLPARWGSVRFPGKPLAMILGKSLIQRTYENIIQSETLDKVVVATDDQRIMDHVLDFGGACLMTSPEC
ANGTERMAETVSRYFPEAEIMVNIQGDEPCLRHTVVDALVRKLEEHPEIQMVTPVAQTTDSHEILTNQKVKCVFDKNGKA
LYFSRSPIPHILKKETPIYLHIGVYAFRRSALFSYIASAPSPLSQAEDLEQLRVLEHGGSIHVCVVEAKSPSVDYPEDIS
KVEEYLTCHSSASF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-36 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-36 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-36 41