Gene Information

Name : CAB036 (CAB036)
Accession : YP_219468.1
Strain : Chlamydophila abortus S26/3
Genome accession: NC_004552
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 44048 - 45376 bp
Length : 1329 bp
Strand : +
Note : Similar to Chlamydia pneumoniae YopN or YscN or cpn0707 or cp0039 SWALL:Q9Z7J8 (EMBL:AE001652) (442 aa) fasta scores: E(): 5.8e-152, 95.24% id in 442 aa, and to Yersinia enterocolitica probable ATP synthase YscN SWALL:YSCN_YEREN (SWALL:P40290) (439 aa) fa

DNA sequence :
ATGGACGAATTGACGACAGATTTCGATACCCTCATGTCGCAATTGAACGACGTACACTTGACTACCGTTGTCGGTCGTAT
AACTGAAGTCGTCGGTATGTTAATTAAAGCTGTCGTTCCCAATGTACGCGTTGGGGAGGTATGCTTAGTTAAACGTTATG
GTATGGAGCCGCTCGTGACCGAAGTCGTCGGCTTCACACAAAATTTCGCTTTTTTATCGCCACTAGGAGAACTTACTGGA
GTCAGCCCTTCTTCAGAGGTTATTCCCACAGGTCTGCCTTTGTATATCCGTGCAGGTAACGGTCTTTTAGGTCGTGTATT
GAATGGTCTGGGAGAACCTATCGACTCCGAGATCAAAGGACCTTTGGTTGATGTTAACGAAACCTACCCTGTGTTTCGCG
CTCCACCAGATCCATTGCATAGAGAAAAATTAAGAACAATTTTATCCACCGGCGTGCGGTGTATCGACGGTATGCTCACA
GTCGCCAGAGGCCAGCGTATAGGCATTTTTGCTGGAGCTGGGGTGGGTAAATCGTCTCTCTTGGGAATGATCGCTAGAAA
CGCGGAAGAAGCCGATGTCAATGTGATTGCTCTCATCGGAGAGCGGGGCCGAGAGGTTCGTGAATTTATCGAGGGCGATC
TCGGAGAAGAAGGAATGAAACGTTCGGTGATCGTCGTCTCTACTTCAGATCAATCCTCACAGTTGCGATTAAATGCTGCT
TACGTAGGCACCGCTATAGCAGAGTATTTTCGTGATCAGGGCAAAACCGTAGTTTTGATGATGGATTCTGTCACCCGATT
TGCCCGAGCCCTAAGAGAAGTCGGTCTAGCTGCCGGAGAACCGCCAGCTCGAGGAGGATACACACCTTCTGTATTCTCAA
CTTTGCCTAGGTTATTAGAACGTTCCGGAGCTTCGGATAAAGGAACAATCACAGCCTTTTACACAGTACTTGTTGCCGGG
GATGATATGAATGAACCGGTCGCTGATGAAGTTAAATCGATTCTTGATGGTCACGTTGTCTTGTCTAACGCTTTAGCTCA
GGCATACCATTATCCTGCTATTGATGTCTTAGCATCTATCAGCCGATTGCTGACAGCAATTGTTCCTGAGGAACAACGAC
GCATCATAGGAAAAGCCCGAGAGGTGCTGGCAAAATACAAAGCAAACGAAATGCTTATACGTATTGGAGAATATCGCCGA
GGGTCCGATCGTGAAGTGGATTTTGCTATAGATCACATTGATAAATTGAACAGATTCTTAAAGCAAGATATTCATGAAAA
AACAAATTACGAGGAAGCCTCGCAACAGCTTCGGGCTATTTTCCGATAA

Protein sequence :
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRYGMEPLVTEVVGFTQNFAFLSPLGELTG
VSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDSEIKGPLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARGGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHVVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREVDFAIDHIDKLNRFLKQDIHEKTNYEEASQQLRAIFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-104 56
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-78 55
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-78 55
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-93 53
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-92 52
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-92 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-92 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 8e-94 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 8e-94 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-94 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-92 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-93 52
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-80 51
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 6e-79 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-79 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-79 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-79 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-79 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-74 47
escN AAK26715.1 EscN Virulence LEE Protein 2e-81 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-81 47
escN AAL57542.1 EscN Virulence LEE Protein 2e-81 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-81 47
escN AAC31513.1 L0034 Virulence LEE Protein 2e-81 47
unnamed AAL06369.1 EscN Virulence LEE Protein 4e-79 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-81 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 2e-81 47
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-81 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 8e-82 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-81 47
escN AAC38383.1 EscN Virulence LEE Protein 3e-81 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-81 47
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-77 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 5e-77 47
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-82 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 7e-72 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-76 46
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-66 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-71 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-71 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-85 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-79 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-79 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-79 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 4e-67 43
invC AAS66861.1 InvC Not tested SSR-2 Protein 2e-66 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-63 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 5e-63 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-63 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CAB036 YP_219468.1 type III secretion system ATPase VFG2144 Protein 0.0 92
CAB036 YP_219468.1 type III secretion system ATPase VFG0192 Protein 6e-109 57
CAB036 YP_219468.1 type III secretion system ATPase VFG0390 Protein 2e-103 56
CAB036 YP_219468.1 type III secretion system ATPase VFG0048 Protein 2e-104 55
CAB036 YP_219468.1 type III secretion system ATPase VFG0515 Protein 2e-79 50
CAB036 YP_219468.1 type III secretion system ATPase VFG0812 Protein 1e-81 47
CAB036 YP_219468.1 type III secretion system ATPase VFG0730 Protein 2e-81 47
CAB036 YP_219468.1 type III secretion system ATPase VFG2459 Protein 4e-68 45
CAB036 YP_219468.1 type III secretion system ATPase VFG2499 Protein 4e-76 45
CAB036 YP_219468.1 type III secretion system ATPase VFG2331 Protein 1e-76 44
CAB036 YP_219468.1 type III secretion system ATPase VFG1254 Protein 4e-78 44
CAB036 YP_219468.1 type III secretion system ATPase VFG0555 Protein 2e-63 43
CAB036 YP_219468.1 type III secretion system ATPase VFG1778 Protein 9e-68 43
CAB036 YP_219468.1 type III secretion system ATPase VFG1008 Protein 4e-61 41