Gene Information

Name : purA (TW801)
Accession : NP_789722.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 908787 - 910076 bp
Length : 1290 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
TTGCCAGCAACAATTCTTATTGGTGCCCAGTGGGGGGATGAAGGCAAGGGAAAGGCCACAGACCTTCTTGCAAAAGATAT
AGATTATGTCGTCAAATTCAACGGCGGTAATAATGCGGGTCACACCGTAGTTATAGGCGGTGATAAGTACGTTCTGCACC
TTCTGCCTTCCGGGATACTCAATGAGAATGTCGTGCCGGTCATTGCAAATGGTGTTGTAATCAATCCGGAGGTGCTTTTT
GATGAAATTGCTACTCTAAATTCACGAGGCGTAAACACGGACAAGCTTGTTATAAGCGCCAACGCTCATATTATTGCGCC
CTTTCACAGAACTATAGATCTTGTGACGGAACGTTTCTTGGGCAAAAGACAGTTGGGAACAACAGGAAGAGGAATAGGCC
CCACATATGCAGACAAAATAAACCGCATTGGTATACGGGTACAAGATTTATTTGATAAAAGCGTACTGCGACAAAAAATT
GAGGGGTCTTTGAGTAATAAAAATCATATGCTCGTAAAAGTTTTTAACCGCAGATCTGTGTCTGTAACGGAAATGCTGGA
TTATTTACTTAGTTTTGCTGAGCGTATGAGGCCGATGATCGCGGACACATCACTTTTGCTAAATAATGCTTTGGATTGCG
GAAAACATGTCCTATTCGAGGGGGGTCAGGCGACTATGCTTGATGTCGATCATGGAAGTTACCCATTTGTCACTTCGTCC
AATGCAACGGTCGGAGGGGCAATAACAGGGGCAGGGATTGGCCCAACTCGTGTGAACAAAGTTATCGGAGTGGCCAAATC
GTACACAACTAGGGTAGGCGCAGGGCCATTTCCAACTGAATTGCATGACGAATATGGGGAGTGGCTACAAAAAAGAGGTT
ATGAGGTAGGAGCAACTACAGGACGCAAGAGGCGGTGTGGGTGGTTTGACGGTGTGGTCGCCCGCTATGCGACTCGTATA
AACGGGATAACGGACTACGTTCTGACAAAACTCGATGTTTTGACGGGCCTTGACAGAATACCTATCTGCGTCGGGTATAA
AGTTGGAGACTCTGTCTTTCGGGAAATGCCTGTCTCGCAGAGTGATTTTCACCACGCAGTTCCCATATACGAGGATCTGC
CCGGATGGCAGTGCAATATTTCCGAATGCGAAAGTTTTGACAGTCTTCCTCCGGAAGCAAGGGGCTATGTCTTGGCCCTG
GAGGATCTTATAAAGGCACGAATATCAGTCATTGGAACAGGTCCAGAGCGGGAAAATATAATCATTAGGCACCCGCTGGG
CATCTTCTAG

Protein sequence :
MPATILIGAQWGDEGKGKATDLLAKDIDYVVKFNGGNNAGHTVVIGGDKYVLHLLPSGILNENVVPVIANGVVINPEVLF
DEIATLNSRGVNTDKLVISANAHIIAPFHRTIDLVTERFLGKRQLGTTGRGIGPTYADKINRIGIRVQDLFDKSVLRQKI
EGSLSNKNHMLVKVFNRRSVSVTEMLDYLLSFAERMRPMIADTSLLLNNALDCGKHVLFEGGQATMLDVDHGSYPFVTSS
NATVGGAITGAGIGPTRVNKVIGVAKSYTTRVGAGPFPTELHDEYGEWLQKRGYEVGATTGRKRRCGWFDGVVARYATRI
NGITDYVLTKLDVLTGLDRIPICVGYKVGDSVFREMPVSQSDFHHAVPIYEDLPGWQCNISECESFDSLPPEARGYVLAL
EDLIKARISVIGTGPERENIIIRHPLGIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 7e-96 48