Gene Information

Name : TW687 (TW687)
Accession : NP_789608.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Virulence
Product : ABC transporter integral membrane subunit
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 775284 - 776138 bp
Length : 855 bp
Strand : +
Note : Similar to Synechocystis sp. manganese transport system membrane protein MntB or sll1600 SWALL:MNTB_SYNY3 (SWALL:Q55282) (306 aa) fasta scores: E(): 6.7e-40, 43.41% id in 258 aa

DNA sequence : 
GTGATTGATTATCTACTTGCTCCTTTCGAGTACGGGTTCATGCTGCGTGCCTTTATTGTTGTCATTGTGTCAGCAACCCT
GTGCGGCCTCATATCGTGTTGGGTGGTTCTTCTTGGCTGGTCGATGCTCGGTGAGGCAATTTCACACGCGATATTTCCCG
GAGTTGTCCTAAGCTTCCTCCTTGGCGTGCCATTTGCCATTGGCGCTTTTGTATCCGGCCTTGTGGCAGTGTATCTAATC
GGCCACCTGAGAAGTAACCCTAGGATCAAAGAGGATGCTGCGATGGGTGTTGTGTTCATAACCATGTTCTCGCTTGGCCT
AATCTTAGTTTTCTTTATTCCAGGCAAAGGTCATCTTATGCATATATTGTTCGGCAACTTGCTAAGTGTTACATATCTGG
ATCTGTATCAGGTAATAATCCTTGGTGTGCTTGGGATATCGATCCTAACTTATAGGCGAAGGGATTTTACCCTGTACGCA
TTCGACCCCGGACACGCGAATGTCATTGGTATATCCACCAGATCACTTCACAATATATTTCTTATAACCCTAGCGTTCAC
AATTGTTGTCTCGGTACAGCAAGTCGGTGTGGTTCTTGTTGTTGCTATGTTGGTCATACCGGGCGTCTCGGCAAGTCTGC
TTAGCAGAAAAATATCAAGAATGTTTATCATATCTCCCGTCATGGCTGTTACAACTTCTGTAGCTGGTGTTTACATAAGC
TACACATTTGACTTACCACCGGGATCGGTGATTGTCTTGGTTATGGGATCAGTGTTCGTTCTCACATACACTGTAACGAG
TATCATGTCAATGATTGTGAGCAATAGAACTCTGTTGAGGACAAGACACGGGTAA

Protein sequence : 
MIDYLLAPFEYGFMLRAFIVVIVSATLCGLISCWVVLLGWSMLGEAISHAIFPGVVLSFLLGVPFAIGAFVSGLVAVYLI
GHLRSNPRIKEDAAMGVVFITMFSLGLILVFFIPGKGHLMHILFGNLLSVTYLDLYQVIILGVLGISILTYRRRDFTLYA
FDPGHANVIGISTRSLHNIFLITLAFTIVVSVQQVGVVLVVAMLVIPGVSASLLSRKISRMFIISPVMAVTTSVAGVYIS
YTFDLPPGSVIVLVMGSVFVLTYTVTSIMSMIVSNRTLLRTRHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-38 41
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 3e-38 41
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 3e-38 41
sitD NP_461785.1 permease Virulence SPI-1 Protein 2e-38 41
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 2e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TW687 NP_789608.1 ABC transporter integral membrane subunit BAC0442 Protein 2e-41 45
TW687 NP_789608.1 ABC transporter integral membrane subunit BAC0352 Protein 1e-38 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TW687 NP_789608.1 ABC transporter integral membrane subunit VFG0528 Protein 1e-38 41