Gene Information

Name : TW686 (TW686)
Accession : NP_789607.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Virulence
Product : ABC transporter ATP-binding subunit
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1121
EC number : -
Position : 774394 - 775203 bp
Length : 810 bp
Strand : +
Note : Similar to Synechocystis sp. manganese transport system ATP-binding protein MntA or sll1599 SWALL:MNTA_SYNY3 (SWALL:Q55281) (260 aa) fasta scores: E(): 6.6e-34, 46.18% id in 236 aa

DNA sequence : 
GTGCTGAGAGGCTCCGTCCTGTCTGTCAGTGACTTGTCAGTGGTTTATGGCGACGTTGTTGCTATGAGGGATGCAACATT
TGAGGTTGCTTCAGGGGTTGTTTGTGGCATCATAGGGATGAACGGCTCGGGTAAGTCGAGCCTATTCAACTCGATTGTTG
GCAACGTAAGGCCAGCACGTGGTAGCATCTCGATATTTGGTCTTTCCCCCGTTGCCGCAATGAAACGGGGGATGGTAGCT
TATGCCCCACAACGCGAATCAATTGACTGGAACTTTCCGATAAGTGTGCGTGAGGTGGTTATGATGGGGCGATATGGTTT
TATGTCATTGTCCCGAAGGGCGAGTCAAACTGATCGCGATAAGGTCACACAGGCCCTCGAAATGACTGAACTTGTGGAGC
TTGCAGATAGGCAAATTGGGCAACTCTCTGGAGGGCAGAAGAAAAGGGCATTTGTCGCGAGGGCAATAGCACAGGGCGCC
AAGCTGCTTCTCCTTGACGAGCCATTTGCCGGAGTTGATAAAAAGAGCGAGGGAATGATTGTGCAGCTTATTCGCCAGCT
CTGTGAGAAGGGGTGCTGTGTTCTTGTTTCAACCCATGATCTAAACACTCTTCACGGGCTGTGCAATGAGGCGATTCTTG
TTAAAAACCGTATCTTGATGCACAACACGTGTGAGGTTGTTTTGCGTCCGAATAATCTCGCCATGGCGTTTGGACTAGAT
CCGGGTTATGGAACAAGTAAGAATAACAACGATTTAAATACGTTTATATCCGCAACGAGCGCAAATGGAGTCGCGGATGG
TAGCAACTGA

Protein sequence : 
MLRGSVLSVSDLSVVYGDVVAMRDATFEVASGVVCGIIGMNGSGKSSLFNSIVGNVRPARGSISIFGLSPVAAMKRGMVA
YAPQRESIDWNFPISVREVVMMGRYGFMSLSRRASQTDRDKVTQALEMTELVELADRQIGQLSGGQKKRAFVARAIAQGA
KLLLLDEPFAGVDKKSEGMIVQLIRQLCEKGCCVLVSTHDLNTLHGLCNEAILVKNRILMHNTCEVVLRPNNLAMAFGLD
PGYGTSKNNNDLNTFISATSANGVADGSN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitB NP_457256.1 Iron transport protein, ATP-binding component Virulence SPI-1 Protein 7e-52 47
sitB NP_806465.1 iron ABC transporter ATP-binding protein Virulence SPI-1 Protein 7e-52 47
sitB AAD41066.1 SitB Virulence centisome 63 pathogenicity island Protein 6e-51 47
sitB YP_217782.1 iron transporter: fur regulated Virulence SPI-1 Protein 1e-50 47
sitB NP_461783.1 ATP-binding protein Virulence SPI-1 Protein 8e-51 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TW686 NP_789607.1 ABC transporter ATP-binding subunit BAC0350 Protein 4e-51 47
TW686 NP_789607.1 ABC transporter ATP-binding subunit BAC0440 Protein 9e-52 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TW686 NP_789607.1 ABC transporter ATP-binding subunit VFG0526 Protein 3e-51 47