Gene Information

Name : TW068 (TW068)
Accession : NP_789018.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 59134 - 59919 bp
Length : 786 bp
Strand : -
Note : Similar to Escherichia coli ferric enterobactin transport ATP-binding protein FepC or b0588 SWALL:FEPC_ECOLI (SWALL:P23878) (271 aa) fasta scores: E(): 8.6e-42, 50% id in 250 aa

DNA sequence : 
ATGATTACCGTCGATAAGCTTTCGTTTTCTTACGGAAAAAACAAGGTTCTGCACGACATAAGCATAGAGATAAAACGGGG
CTCTTTTATCGCAATTATTGGCGCTAATGGCTGTGGCAAATCAACTTTTTTACGCTCTATTGCCGGACTAAATAGATTTG
AAGGGGATATTCTCCTTGACAAGCAGCATATTCGAAGGTTAAAGCCTAAGAATTTGGCCAAGCATATCGCTTTCCTACCT
CAACAGGTTAATCTCCCGGAAGGGCTAACCATAGCGGATCTTGTGAGCAGGGGGCGATATCCCCATCAAAGCATTCTGCA
TAGATGGACGAAAACTGATGAAGAAGTTGTAAAAGAGTCCCTTCAAGCGGTTCAGGCCTCACATATTTCACAACGAGCCA
TTGAAGCCGTTTCGGGCGGACAGCGCCAGAGGGCCTTGATAGCAATGGTATTAGCTCAGCAGACTCGTATTCTCTTACTC
GACGAACCAACGACGTTTCTTGATATAGCTTATCAATATGAGATTCTTGAACTTTTAGCATCTCTCAACAGAGAAAGCAA
AACTATCATTTGCTCATTACACGACCTTAACCAAGCTGCAAGATATGCATCTCACCTGTTTGTGATGGGAGAAGGCCGGA
TCATTGCCTCGGGCGAACCAAAAAAAGTTATAACAGAAAACTTGATAGAAAATGCATTTGGCTTGAAATCAAGAATAATA
GATGATCCTGAATCTAATACACCCATGATTATTCCCCGCAAATCTGAGAATTTGAAACGATTGTAA

Protein sequence : 
MITVDKLSFSYGKNKVLHDISIEIKRGSFIAIIGANGCGKSTFLRSIAGLNRFEGDILLDKQHIRRLKPKNLAKHIAFLP
QQVNLPEGLTIADLVSRGRYPHQSILHRWTKTDEEVVKESLQAVQASHISQRAIEAVSGGQRQRALIAMVLAQQTRILLL
DEPTTFLDIAYQYEILELLASLNRESKTIICSLHDLNQAARYASHLFVMGEGRIIASGEPKKVITENLIENAFGLKSRII
DDPESNTPMIIPRKSENLKRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-54 46
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-54 46
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 1e-53 46
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 1e-53 46
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 1e-53 46
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 1e-53 46
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 4e-48 43
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 5e-47 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TW068 NP_789018.1 iron-siderophore uptake system ATP-binding component BAC0164 Protein 3e-47 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TW068 NP_789018.1 iron-siderophore uptake system ATP-binding component VFG0925 Protein 9e-64 50
TW068 NP_789018.1 iron-siderophore uptake system ATP-binding component VFG1042 Protein 3e-47 42