Gene Information

Name : TW641 (TW641)
Accession : NP_789566.1
Strain : Tropheryma whipplei TW08/27
Genome accession: NC_004551
Putative virulence/resistance : Unknown
Product : nicotinate phosphoribosyltransferase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1488
EC number : 2.4.2.11
Position : 727985 - 729313 bp
Length : 1329 bp
Strand : +
Note : catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate

DNA sequence :
GTGGGCGGTGCAGGTCTCCTAACAGACCAATACGAGTTGTCGATGGTCAACGCAGCACGAATATCAGGGATAGCTGCTAA
AGAATGTGTTTTTGAGGTTTATTCTCGCGCATTGCCACCTGGCAGGCCATTTGGTGTGTTTGCAGGCCTTGAGAGGCTGC
TGGAAAAAATCGAAAATTTCTCCTTTGCAGATGACGAAATTACATGGCTTAGAGAAAAGAATATCGTTGATAATGAGACA
CTTGACTGGCTCCGGGGGTATAGCTTTTCTGGGTCAATTTCTGGCCACAAAGAGGGGGAAATCTTTTTCCCCAATACACC
CGTTCTAACTGTTAGAGCACCATTTGCAGAAGCAGTAGTTCTCGAAACCCTGATCCTAAGTTGCATAAATTTTGATAGCG
CTATTGCGTCAACGGCGGCACAACTTGTGTATCGCGCAAAAAACAAACCAGTTTATGAAATGGGCTCCAGAAGAACAAAT
GAACAGGCCGCTGTAGCAGCGGCACGCGCTGCGTACATTGCTGGGTTTGCTGCAACAAGCAATCTGGCAGCTGGGAAGAT
TTGGGATATACCAACCGTTGGAACTATGGGTCATGCATTTATACTTGCTCATAAAACGGAGAGTGAAGCTTTTTATGCAC
AGGTCAAACAGGGTGGGGGAAACAATATAACCCTCTTGATTGATACATACGATATCCAGGAAGCAATTGACAGTGCGGTA
ACTGTCGCAGGCAAAAATCTTGCAGCTGTAAGAATAGATTCGGGAAACCTACCAGAAGTGGTGCACGATGTACGCAGAAA
GCTCGACCTCGCGGGTGCAACTGAGACAAAGATCATTCTTACAGGCGACCTTGATGAGGCCTCAATTAGGCTCGTAAGCA
CCGCACCAGTTGATGCACTCGGGGTTGGAACATCTCTGGTAACTGCGGGAGGATTTCCATCTGCAGGCTTTGTTTATAAA
CCGGTGGCATGCAGAGAAAAAAACAGATGGAGAATGCTTTCGAAAAAATCAAAAAACAAAGTTAGCACCGGCGGGCAAAA
AAATGTCCAAAGAGTTCTTGACAAAAACAAGAAGATTATCAAAGAGCAAGTCCTTGTATTTGATCCCGATAATCCCCCAG
TGACAACCTATGACACGAATGTATTACAGATTACGAGTGAACATATAAGGTACGGAAAAAGAGTTGCAATAAACTCAACA
AATGAAATAAGGGCGTATCACAAATCGGTTATCAACCAAATCCCAGAAGAAGTATTCAACCTTGAGGGCAAAATAAATAC
CGAGCGGATCTCCTGGCATAGTGTGCAAGGCCATCGTCTAGAGGCCTAG

Protein sequence :
MGGAGLLTDQYELSMVNAARISGIAAKECVFEVYSRALPPGRPFGVFAGLERLLEKIENFSFADDEITWLREKNIVDNET
LDWLRGYSFSGSISGHKEGEIFFPNTPVLTVRAPFAEAVVLETLILSCINFDSAIASTAAQLVYRAKNKPVYEMGSRRTN
EQAAVAAARAAYIAGFAATSNLAAGKIWDIPTVGTMGHAFILAHKTESEAFYAQVKQGGGNNITLLIDTYDIQEAIDSAV
TVAGKNLAAVRIDSGNLPEVVHDVRRKLDLAGATETKIILTGDLDEASIRLVSTAPVDALGVGTSLVTAGGFPSAGFVYK
PVACREKNRWRMLSKKSKNKVSTGGQKNVQRVLDKNKKIIKEQVLVFDPDNPPVTTYDTNVLQITSEHIRYGKRVAINST
NEIRAYHKSVINQIPEEVFNLEGKINTERISWHSVQGHRLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1473 YP_001800867.1 nicotinate phosphoribosyltransferase Not tested Not named Protein 4e-62 47